| MP:0000137 | abnormal vertebrae morphology | "malformed bony segment of the spinal column" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8] |
Show
Allelic Composition: Mycntm2.1Nagy/Mycntm2.1Nagy
Genetic Background: involves: 129S1/Sv * 129X1/SvJ
|
| MP:0000260 | abnormal angiogenesis | "aberrant process of blood vessel formation and the subsequent remodeling process; does not refer to the initial establishment of the vascular network" [J:67296, csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
Show
Allelic Composition: Mycntm2.1Nagy/Mycntm2.1Nagy
Genetic Background: involves: 129S1/Sv * 129X1/SvJ
|
| MP:0000267 | abnormal cardiac development | "aberrant formation or incomplete differentiation of the heart" [MGI:cls, J:53370] |
Show
Allelic Composition: Pax6Sey/Pax6Sey
Genetic Background: involves: C57BL/6J * DBA/2J
|
| MP:0000295 | poorly developed ventricular trabeculae | "retarded differentation of the supporting bundles of muscular fibers lining the walls of the ventricles of the heart" [J:29971] |
Show
Allelic Composition: Pax6Sey/Pax6Sey
Genetic Background: involves: C57BL/6J * DBA/2J
Allelic Composition: Mycntm1Knd/Mycntm1Knd
Genetic Background: involves: 129P2/OlaHsd * BALB/c
|
| MP:0000433 | microcephaly | "an abnormally small head" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
Show
Allelic Composition: Thrbtm1Df/Thrbtm1Df
Genetic Background: involves: 129S1/Sv * C57BL/6J * FVB/NJ
|
| MP:0000470 | abnormal stomach morphology | "malformation of the sac-like structure of the digestive canal between the esophagus and the small intestine" [Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
Show
Allelic Composition: Nr5a1tm2Klp/Nr5a1tm2Klp,Tg(Cga-cre)3Sac/0
Genetic Background: involves: 129P2/OlaHsd * C57BL/6J * SJL
|
| MP:0000488 | abnormal intestinal epithelium morphology | "anomalous structure or development of the cellular avascular layer of the digestive tube passing from the stomach to the anus" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
Show
Allelic Composition: Mycntm1Par/Mycntm1Par
Genetic Background: involves: 129S2/SvPas * C57BL/6J
|
| MP:0000489 | abnormal large intestine morphology | "structural or developmental anomalies of the intestinum crassum " [Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
Show
Allelic Composition: Mycntm1Par/Mycntm1Par
Genetic Background: involves: 129S2/SvPas * C57BL/6J
|
| MP:0000564 | syndactyly | "any degree of webbing or fusion of the digits, may involve only soft tissues or also can include bone" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8] |
Show
Allelic Composition: Brca2tm1Brn/Brca2tm1Brn,Trp53bp1tm1Jc/Trp53bp1tm1Jc,Cd19tm1(cre)Cgn/Cd19+
Genetic Background: involves: 129P2/OlaHsd
|
| MP:0000585 | kinked tail | "a sharp bend or zig-zag in the tail" [J:61295] |
Show
Allelic Composition: Mycntm1Nagy/Mycntm2.1Nagy
Genetic Background: involves: 129S1/Sv * 129X1/SvJ
Allelic Composition: Mycntm2.1Nagy/Mycn+
Genetic Background: involves: 129S1/Sv * 129X1/SvJ
|
| MP:0000596 | abnormal liver development | "anomalous differentiation of the liver" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator] |
Show
Allelic Composition: Nr5a1tm2Klp/Nr5a1tm2Klp,Tg(Cga-cre)3Sac/0
Genetic Background: involves: 129P2/OlaHsd * C57BL/6J * SJL
Allelic Composition: Mycntm1Fwa/Mycntm1Fwa
Genetic Background: involves: 129S/SvEv
|
| MP:0000598 | abnormal liver morphology | "malformation or absence of this bile-secreting exocrine gland, which is important for detoxification; for fat, carbohydrate, and protein metabolism; and for glycogen storage " [Stedman s Medical Dictionary:ISBN 0-683-40008-8, MGI:CLS, J:23170] |
Show
Allelic Composition: Gria1tm1Rsp/Gria1tm1Rsp
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6J * CBA/J
|
| MP:0000600 | liver hypoplasia | "reduced size of liver due to decreased cell number " [J:57631] |
Show
Allelic Composition: Mycntm1Fwa/Mycntm1Fwa
Genetic Background: involves: 129S/SvEv
|
| MP:0000601 | small liver | "reduced size of the liver" [J:23170] |
Show
Allelic Composition: Nr5a1tm2Klp/Nr5a1tm2Klp,Tg(Cga-cre)3Sac/0
Genetic Background: involves: 129P2/OlaHsd * C57BL/6J * SJL
Allelic Composition: Mycntm1Fwa/Mycntm1Fwa
Genetic Background: involves: 129S/SvEv
|
| MP:0000774 | reduced brain size | "smaller appearance of the brain" [J:35802] |
Show
Allelic Composition: Thrbtm1Df/Thrbtm1Df
Genetic Background: involves: 129S1/Sv * C57BL/6J * FVB/NJ
Allelic Composition: Mycntm1.1Mlit/Mycntm1.1Mlit,Tg(CAG-tTS)1Mlit/0
Genetic Background: involves: 129S6/SvEvTac * C57BL/6 * C57BL/6J
|
| MP:0000785 | telencephalon hypoplasia | "reduced cell number in cerebral cortex and basal ganglia" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:45302] |
Show
Allelic Composition: Mycntm1Par/Mycntm1Par
Genetic Background: involves: 129S2/SvPas * C57BL/6J
|
| MP:0000786 | abnormal neuroepithelial layer differentiation | "malformation or arrest of differentiation or patterning of the epithelial layer of the brain" [J:45302] |
Show
Allelic Composition: Mycntm1Par/Mycntm1Par
Genetic Background: involves: 129S2/SvPas * C57BL/6J
|
| MP:0000788 | abnormal cerebral cortex morphology | "malformed gray cellular mantle covering the surface of the brain" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, J:38857] |
Show
Allelic Composition: Thrbtm1Df/Thrbtm1Df
Genetic Background: involves: 129S1/Sv * C57BL/6J * FVB/NJ
|
| MP:0000846 | abnormal medulla oblongata | "anomaly in the most caudal region of the brainstem that lies directly rostral to the spinal cord; includes regions responsible for autonomic functions such as digestion, breathing and control of heart rate" [Principles of Neural Science , 3rd edition:ISBN 0-8385-8034-3] |
Show
Allelic Composition: Mycntm1Par/Mycntm1Par
Genetic Background: involves: 129S2/SvPas * C57BL/6J
|
| MP:0000849 | abnormal cerebellum morphology | "any malformation or absence of the part of the metencephalon that lies in the posterior cranial fossa dorsal to the pons and medulla that is concerned with the coordination of movement and learning of motor skills" [J:50311, Principles of Neural Science , 3rd edition:ISBN 0-8385-8034-3] |
Show
Allelic Composition: Thrbtm1Df/Thrbtm1Df
Genetic Background: involves: 129S1/Sv * C57BL/6J * FVB/NJ
|
| MP:0000852 | small cerebellum | "reduced size of cerebellum" [MGI:CLS, J:17203, J:67524] |
Show
Allelic Composition: Thrbtm1Df/Thrbtm1Df
Genetic Background: involves: 129S1/Sv * C57BL/6J * FVB/NJ
Allelic Composition: Mycntm1.1Mlit/Mycntm1.1Mlit,Tg(CAG-tTS)1Mlit/0
Genetic Background: involves: 129S6/SvEvTac * C57BL/6 * C57BL/6J
|
| MP:0000854 | abnormal cerebellum development | "malformed or incomplete differentiation of the part of the metencephalon that lies dorsal to the pons and medulla behind the brain stem and controls balance for walking and standing, modulates the force and range of movement and is involved in the learning of motor skills " [MeSH:National Library of Medicine - Medical Subject Headings , 2003, Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8] |
Show
Allelic Composition: Thrbtm1Df/Thrbtm1Df
Genetic Background: involves: 129S1/Sv * C57BL/6J * FVB/NJ
Allelic Composition: Mycntm1.1Mlit/Mycntm1.1Mlit,Tg(CAG-tTS)1Mlit/0
Genetic Background: involves: 129S6/SvEvTac * C57BL/6 * C57BL/6J
|
| MP:0000857 | abnormal cerebellar foliation | "malformation of small offshoots of the cerebellar lobules" [Principles of Neural Science:ISBN 0-8385-8034-3, J:52951] |
Show
Allelic Composition: Thrbtm1Df/Thrbtm1Df
Genetic Background: involves: 129S1/Sv * C57BL/6J * FVB/NJ
|
| MP:0000872 | abnormal external granule cell layer | "malformation of the transient layer of the cerebellar cortex which is composed of the dividing and migrating granule cells" [tc:Teresa Chu , Mouse Genome Informatics Curator] |
Show
Allelic Composition: Thrbtm1Df/Thrbtm1Df
Genetic Background: involves: 129S1/Sv * C57BL/6J * FVB/NJ
|
| MP:0000875 | abnormal cerebellar Purkinje cell layer | "any malformation or absence of the cell layer that lies just underneath the molecular layer of the cerebellar cortex; it contains the neuronal cell bodies of the Purkinje cells that are arranged side by side in a single layer, and candelabrum interneurons are vertically oriented between the Purkinje cells" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8] |
Show
Allelic Composition: Thrbtm1Df/Thrbtm1Df
Genetic Background: involves: 129S1/Sv * C57BL/6J * FVB/NJ
|
| MP:0000880 | decreased Purkinje cell number | "fewer than normal neuronal cells that are located in the interface of the molecular and granular layers of the cerebellar cortex" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, J:45302] |
Show
Allelic Composition: Thrbtm1Df/Thrbtm1Df
Genetic Background: involves: 129S1/Sv * C57BL/6J * FVB/NJ
|
| MP:0000885 | ectopic Purkinje cell | "Purkinje cell body resides in places other than the Purkinje cell layer in the cerebellum" [MGI:tc, J:60896] |
Show
Allelic Composition: Thrbtm1Df/Thrbtm1Df
Genetic Background: involves: 129S1/Sv * C57BL/6J * FVB/NJ
|
| MP:0000886 | abnormal cerebellar granule layer | "any malformation or absence of the innermost cortical layer of the cerebellum; contains densly packed small neurons, mostly granule cells with some Golgi cells are found at the outer border" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, Principles of Neural Science , 3rd edition:ISBN 0-8385-8034-3] |
Show
Allelic Composition: Thrbtm1Df/Thrbtm1Df
Genetic Background: involves: 129S1/Sv * C57BL/6J * FVB/NJ
|
| MP:0000889 | abnormal cerebellar molecular layer | "any malformation or absence of the outermost layer of the cerebral cortex that contains the parallel fibers of the granule cells, interneurons such as stellate and basket cells, and the dendrites of the underlying Purkinje cells" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:38857] |
Show
Allelic Composition: Thrbtm1Df/Thrbtm1Df
Genetic Background: involves: 129S1/Sv * C57BL/6J * FVB/NJ
|
| MP:0000962 | disorganized dorsal root ganglia | "loss of segmentation pattern of DRGs; loss of regular spacing " [J:62022, J:62023] |
Show
Allelic Composition: Mycntm1Par/Mycntm1Par
Genetic Background: involves: 129S2/SvPas * C57BL/6J
|
| MP:0000964 | small dorsal root ganglia | "reduced size of the dorsal root ganglia" [J:17123] |
Show
Allelic Composition: Pax6Sey/Pax6Sey
Genetic Background: involves: C57BL/6J * DBA/2J
Allelic Composition: Mycntm1Knd/Mycntm1Knd
Genetic Background: involves: 129P2/OlaHsd * BALB/c
Allelic Composition: Mycntm1Par/Mycntm1Par
Genetic Background: involves: 129S2/SvPas * C57BL/6J
|
| MP:0001081 | abnormal cranial ganglia morphology | "any anomaly, deformity, or malformation of the groups of nerve cell bodies associated with the twelve cranial nerves" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, MGI:cls, J:45302] |
Show
Allelic Composition: Pax6Sey/Pax6Sey
Genetic Background: involves: C57BL/6J * DBA/2J
Allelic Composition: Mycntm1Par/Mycntm1Par
Genetic Background: involves: 129S2/SvPas * C57BL/6J
|
| MP:0001093 | small trigeminal ganglion | "reduced size of the trigeminal ganglion" [J:25565, J:17123] |
Show
Allelic Composition: Pax6Sey/Pax6Sey
Genetic Background: involves: C57BL/6J * DBA/2J
Allelic Composition: Mycntm1Par/Mycntm1Par
Genetic Background: involves: 129S2/SvPas * C57BL/6J
|
| MP:0001175 | abnormal lung morphology | "malformed organ of respiration" [J:35802] |
Show
Allelic Composition: Pax6Sey/Pax6Sey
Genetic Background: involves: C57BL/6J * DBA/2J
Allelic Composition: Mycntm1Psk/Mycntm1Psk,Tg(Sftpc-cre)1Blh/0
Genetic Background: involves: 129 * C57BL/6 * ICR
Allelic Composition: Mycntm1Psk/Mycn+,Tg(Sftpc-cre)1Blh/0
Genetic Background: involves: 129 * C57BL/6 * ICR
|
| MP:0001176 | abnormal lung development | "malformation or arrest of differentiation of the organs of respiration" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:54931] |
Show
Allelic Composition: Mycntm2.1Nagy/Mycntm2.1Nagy
Genetic Background: involves: 129S1/Sv * 129X1/SvJ
Allelic Composition: Mycntm1Psk/Mycntm1Psk,Tg(Sftpc-cre)1Blh/0
Genetic Background: involves: 129 * C57BL/6 * ICR
Allelic Composition: Mycntm1Psk/Mycn+,Tg(Sftpc-cre)1Blh/0
Genetic Background: involves: 129 * C57BL/6 * ICR
Allelic Composition: Mycntm1Par/Mycntm1Par
Genetic Background: involves: 129S2/SvPas * C57BL/6J
|
| MP:0001178 | pulmonary hypoplasia | "reduced size of the respiratory organ due to incomplete development of all or part of the organ " [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, Pathology , 2nd edition:ISBN 0-397-51047-0] |
Show
Allelic Composition: Mycntm1Par/Mycntm1Par
Genetic Background: involves: 129S2/SvPas * C57BL/6J
|
| MP:0001258 | decreased body length | "decreased crown to tail distance compared to controls" [cwg:Carroll W. Goldsmith, Mouse Genome Informatics Curator] |
Show
Allelic Composition: Nr5a1tm2Klp/Nr5a1tm2Klp,Tg(Cga-cre)3Sac/0
Genetic Background: involves: 129P2/OlaHsd * C57BL/6J * SJL
|
| MP:0001292 | abnormal lens vesicle development | "malformation or abnormal patterning of the lens vesicle of the eye" [J:49424] |
Show
Allelic Composition: Pax6Sey/Pax6Sey
Genetic Background: involves: C57BL/6J * DBA/2J
|
| MP:0001297 | microphthalmia | "reduced average size of the eyes" [J:18048] |
Show
Allelic Composition: Thrbtm1Df/Thrbtm1Df
Genetic Background: involves: 129S1/Sv * C57BL/6J * FVB/NJ
|
| MP:0001404 | no spontaneous movement | "failure to make any change in position or posture" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, MGI:CLS, J:60159] |
Show
Allelic Composition: Pax6Sey/Pax6Sey
Genetic Background: involves: C57BL/6J * DBA/2J
|
| MP:0001577 | anemia | "less than normal levels of red blood cells, hemoglobin or volume of packed red blood cells " [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:53370] |
Show
Allelic Composition: Mycntm1Par/Mycntm1Par
Genetic Background: involves: 129S2/SvPas * C57BL/6J
|
| MP:0001672 | abnormal embryogenesis/ development | "anomaly in the establishment of the characteristic configuration of the embryonic body" [Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
Show
Allelic Composition: Myogtm3Whk/Myogtm3Whk,Tg(CAG-cre/Esr1*)5Amc/0
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6 * CBA
|
| MP:0001676 | abnormal apical ectodermal ridge | "malformation of the multilayered ectodermal region at the tip of a limb bud necessary for the proper development of the underlying mesenchyme" [MGI:tc] |
Show
Allelic Composition: Nr5a1tm2Klp/Nr5a1tm2Klp,Tg(Cga-cre)3Sac/0
Genetic Background: involves: 129P2/OlaHsd * C57BL/6J * SJL
|
| MP:0001698 | reduced embryo size | "smaller proportions of embryo compared to littermates" [J:61790] |
Show
Allelic Composition: Pax6Sey/Pax6Sey
Genetic Background: involves: C57BL/6J * DBA/2J
Allelic Composition: Mycntm1Nagy/Mycntm2.1Nagy
Genetic Background: involves: 129S1/Sv * 129X1/SvJ
Allelic Composition: Mycntm1Par/Mycntm1Par
Genetic Background: involves: 129S2/SvPas * C57BL/6J
Allelic Composition: Mycntm1Jrt/Mycntm1Par
Genetic Background: involves: 129S2/SvPas * C57BL/6J
|
| MP:0001719 | absent vitelline blood vessels | "missing vasculature of the yolk sac" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:62571, J:12623] |
Show
Allelic Composition: Mycntm2.1Nagy/Mycntm2.1Nagy
Genetic Background: involves: 129S1/Sv * 129X1/SvJ
|
| MP:0001722 | pale yolk sac | "bloodless yolk sac" [J:62571] |
Show
Allelic Composition: Mycntm2.1Nagy/Mycntm2.1Nagy
Genetic Background: involves: 129S1/Sv * 129X1/SvJ
|
| MP:0001730 | embryonic growth arrest | "the cessation of development beyond a particular stage" [J:17509] |
Show
Allelic Composition: Mycntm1Par/Mycntm1Par
Genetic Background: involves: 129S2/SvPas * C57BL/6J
|
| MP:0001732 | postnatal growth retardation | "slow or limited development after birth " [Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
Show
Allelic Composition: Thrbtm1Df/Thrbtm1Df
Genetic Background: involves: 129S1/Sv * C57BL/6J * FVB/NJ
|
| MP:0001785 | edema | "an accumulation of an excessive amount of watery fluid in cells or intercellular tissues" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:54065] |
Show
Allelic Composition: Mycntm1Par/Mycntm1Par
Genetic Background: involves: 129S2/SvPas * C57BL/6J
|
| MP:0001914 | hemorrhage | "loss of blood from the vascular compartment to the exterior or into nonvascular body space as a result of rupture or severance of the blood vessels" [Stedman s Medical Dictionary, 27th edition:ISBN 0-683-40008-8] |
Show
Allelic Composition: Mycntm1Par/Mycntm1Par
Genetic Background: involves: 129S2/SvPas * C57BL/6J
|
| MP:0001953 | respiratory failure | "cessation of or failure to commence breathing" [MGI:cls, J:60159] |
Show
Allelic Composition: Mycntm2.1Nagy/Mycntm2.1Nagy
Genetic Background: involves: 129S1/Sv * 129X1/SvJ
|
| MP:0001954 | respiratory distress | "physical difficulty or inability to breathe" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:54931] |
Show
Allelic Composition: Pax6Sey/Pax6Sey
Genetic Background: involves: C57BL/6J * DBA/2J
|
| MP:0002151 | abnormal neural tube morphology/development | "anomalous structure of or development of the embryonic neural tube resulting in structural anomaly" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
Show
Allelic Composition: Nr5a1tm2Klp/Nr5a1tm2Klp,Tg(Cga-cre)3Sac/0
Genetic Background: involves: 129P2/OlaHsd * C57BL/6J * SJL
|
| MP:0002152 | abnormal brain morphology | "anomalous structure of or abnormal development of the brain, one of the two components of the central nervous system and the center of thought and emotion; controls coordination, bodily activities and the interpretation of information from the senses (sight, hearing, smell, etc.)" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator, http://cancerweb.ncl.ac.uk] |
Show
Allelic Composition: Nr5a1tm2Klp/Nr5a1tm2Klp,Tg(Cga-cre)3Sac/0
Genetic Background: involves: 129P2/OlaHsd * C57BL/6J * SJL
|
| MP:0002169 | no phenotype detected | "normal, viable and fertile appearance and behavior; indistinguishable from controls" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
Show
Allelic Composition: Mycntm2.1Nagy/Mycn+
Genetic Background: involves: 129S1/Sv * 129X1/SvJ
|
| MP:0002175 | low brain weight | "lower than average weight of the brain" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
Show
Allelic Composition: Mycntm1.1Mlit/Mycntm1.1Mlit,Tg(CAG-tTS)1Mlit/0
Genetic Background: involves: 129S6/SvEvTac * C57BL/6 * C57BL/6J
|
| MP:0002188 | small heart | "reduced size of the heart relative to average" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator, J:67044] |
Show
Allelic Composition: Nr5a1tm2Klp/Nr5a1tm2Klp,Tg(Cga-cre)3Sac/0
Genetic Background: involves: 129P2/OlaHsd * C57BL/6J * SJL
Allelic Composition: Mycntm1Jrt/Mycntm1Par
Genetic Background: involves: 129S2/SvPas * C57BL/6J
|
| MP:0002273 | abnormal alveolar epithelial cell morphology | "any structural anomaly of the cells lining the alveoli " [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator] |
Show
Allelic Composition: Mycntm1Psk/Mycntm1Psk,Tg(Sftpc-cre)1Blh/0
Genetic Background: involves: 129 * C57BL/6 * ICR
|
| MP:0002652 | thin myocardial wall | "thinly developed cardiac muscle layers" [il:Ira Lu , Mouse Genome Informatics Curator, Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8] |
Show
Allelic Composition: Mycntm1Knd/Mycntm1Knd
Genetic Background: involves: 129P2/OlaHsd * BALB/c
Allelic Composition: Mycntm1Nagy/Mycntm2.1Nagy
Genetic Background: involves: 129S1/Sv * 129X1/SvJ
Allelic Composition: Mycntm1Par/Mycntm1Par
Genetic Background: involves: 129S2/SvPas * C57BL/6J
Allelic Composition: Mycntm1Jrt/Mycntm1Par
Genetic Background: involves: 129S2/SvPas * C57BL/6J
|
| MP:0002725 | abnormal vein morphology | "malformation of the blood vessels that carry blood towards the heart" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8] |
Show
Allelic Composition: Mycntm1Jrt/Mycntm1Par
Genetic Background: involves: 129S2/SvPas * C57BL/6J
|
| MP:0002989 | small kidney | "reduced physical bulk one or both of the organs responsible for urine secretion" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
Show
Allelic Composition: Mycntm1Jrt/Mycntm1Par
Genetic Background: involves: 129S2/SvPas * C57BL/6J
|
| MP:0003232 | abnormal forebrain development | "anomaly in the formation or patterning of the anterior primitive cerebral vesicle; most rostral of three primary vesicles of the embryonic neural tube" [J:93081, smb:Susan M Bello, Mouse Genome Informatics Curator] |
Show
Allelic Composition: Mycntm1Par/Mycntm1Par
Genetic Background: involves: 129S2/SvPas * C57BL/6J
|
| MP:0003424 | premature neuronal precursor differentiation | "earlier than normal transformation of neuronal precursor cells into neurons" [smb:Susan M Bello, Mouse Genome Informatics Curator, J:94391] |
Show
Allelic Composition: Thrbtm1Df/Thrbtm1Df
Genetic Background: involves: 129S1/Sv * C57BL/6J * FVB/NJ
|
| MP:0003425 | abnormal optic vesicle formation | "anomalous formation of the hollow outgrowth from the lateral aspects of the embryonic forebrain from which the retina and optic nerve develop" [smb:Susan M Bello, Mouse Genome Informatics Curator, J:94391] |
Show
Allelic Composition: Pax6Sey/Pax6Sey
Genetic Background: involves: C57BL/6J * DBA/2J
|
| MP:0003567 | abnormal cardiomyocyte proliferation | "anomalous division or replication of cardiac muscle cells" [smb:Susan M Bello, Mouse Genome Informatics Curator] |
Show
Allelic Composition: Mycntm1Jrt/Mycntm1Par
Genetic Background: involves: 129S2/SvPas * C57BL/6J
|
| MP:0003827 | abnormal Wolffian duct morphology | "malformation of the transient embryonic tubes that empty into the cloca and degenerate in the male " [MeSH:National Library of Medicine - Medical Subject Headings , 2003] |
Show
Allelic Composition: Mycntm1Par/Mycntm1Par
Genetic Background: involves: 129S2/SvPas * C57BL/6J
|
| MP:0003887 | increased hepatocyte apoptosis | "increase in the number of hepatocytes undergoing programmed cell death" [anna:Anna Anagnostopoulos, Mouse Genome Informatics Curator] |
Show
Allelic Composition: Mycntm1Fwa/Mycntm1Fwa
Genetic Background: involves: 129S/SvEv
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| MP:0003984 | embryonic growth retardation | "slow or limited development before birth" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
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Allelic Composition: Mycntm1Par/Mycntm1Par
Genetic Background: involves: 129S2/SvPas * C57BL/6J
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| MP:0004057 | thin myocardial compact layer | "reduced thickness of the outer, dense layer of the myocardium " [anna:Anna Anagnostopoulos, Mouse Genome Informatics Curator] |
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Allelic Composition: Mycntm1Jrt/Mycntm1Par
Genetic Background: involves: 129S2/SvPas * C57BL/6J
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| MP:0004068 | dilated dorsal aorta | "an expansion in the volume of the dorsal region of the main trunk of the systemic arteries" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
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Allelic Composition: Mycntm1Par/Mycntm1Par
Genetic Background: involves: 129S2/SvPas * C57BL/6J
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| MP:0004200 | reduced fetal size | "smaller proportions of a fetus compared to littermates (sensu Mus: from E14 through birth)" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Mycntm1Jrt/Mycntm1Par
Genetic Background: involves: 129S2/SvPas * C57BL/6J
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| MP:0004261 | abnormal embryonic neuroepithelium morphology | "any structural anomaly in the epithelial cell layer that lines the neural tube and develops into the nervous system and into the neural crest cells" [ISBN:0838580343 "Kandel ER, et al. Principles of Neural Science, 3rd edition", MGI:monikat "Monika Tomczuk, Mouse Genome Informatics Curator"] |
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Allelic Composition: Pax6Sey/Pax6Sey
Genetic Background: involves: C57BL/6J * DBA/2J
Allelic Composition: Mycntm1Psk/Mycntm1Psk,Tg(Nes-cre)1Kln/0
Genetic Background: involves: 129 * C57BL/6 * SJL
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| MP:0004609 | vertebral fusion | "the union of one or more vertebrae into a single structure" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Mycntm2.1Nagy/Mycntm2.1Nagy
Genetic Background: involves: 129S1/Sv * 129X1/SvJ
Allelic Composition: Mycntm1Nagy/Mycntm2.1Nagy
Genetic Background: involves: 129S1/Sv * 129X1/SvJ
Allelic Composition: Mycntm2.1Nagy/Mycn+
Genetic Background: involves: 129S1/Sv * 129X1/SvJ
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| MP:0004670 | small vertebral body | "decreased size of the main cylindrical portion of the vertebra ventral to the vertebral canal" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"] |
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Allelic Composition: Mycntm1Nagy/Mycntm2.1Nagy
Genetic Background: involves: 129S1/Sv * 129X1/SvJ
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| MP:0004784 | abnormal anterior cardinal vein morphology | "any structural anomaly of the two paired veins draining the cephalic part of the body" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"] |
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Allelic Composition: Pax6Sey/Pax6Sey
Genetic Background: involves: C57BL/6J * DBA/2J
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| MP:0004787 | abnormal dorsal aorta morphology | "any structural anomaly of the paired arterial structures of the embryo that supplies each developing somite via efferent segmental arteries; the dorsal aortae articulate with the umbilical arteries, which return mixed blood to the villi of the chorion for reoxygenation" [ISBN:0-914294-08-3 "Gray s Anatomy"] |
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Allelic Composition: Mycntm1Par/Mycntm1Par
Genetic Background: involves: 129S2/SvPas * C57BL/6J
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| MP:0004810 | decreased hematopoietic stem cell number | "reduced cell count of the multipotent, self-renewing stem cells found in the bone marrow and the fetal liver; these give rise to all the types of both the myeloid and lymphoid cell lineages" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Mycntm1Fwa/Mycntm1Fwa
Genetic Background: involves: 129S/SvEv
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| MP:0004948 | abnormal neuronal precursor proliferation | "any anomaly in the ability of a neuroblast population to undergo rapid expansion by cell division" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Mycntm1Psk/Mycntm1Psk,Tg(Nes-cre)1Kln/0
Genetic Background: involves: 129 * C57BL/6 * SJL
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| MP:0004981 | decreased neuronal precursor cell number | "reduced number of the neuroblast embryonic cells that develop into nerve cells or neurons" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Mycntm1Psk/Mycntm1Psk,Tg(Nes-cre)1Kln/0
Genetic Background: involves: 129 * C57BL/6 * SJL
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| MP:0005227 | abnormal vertebral body development | "anomalous formation of the main portion of the vertebra anterior to the vertebral canal, and distinct from the vertebral arch" [Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
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Allelic Composition: Mycntm1Nagy/Mycntm2.1Nagy
Genetic Background: involves: 129S1/Sv * 129X1/SvJ
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| MP:0005650 | abnormal limb bud morphology | "aberrant structure or development of any of the swellings on the trunk of the embryo that become limbs" [hdene:Howard Dene , Mouse Genome Informatics Curator, MeSH:National Library of Medicine - Medical Subject Headings , 2003, J:61460] |
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Allelic Composition: Mycntm1Knd/Mycntm1Knd
Genetic Background: involves: 129P2/OlaHsd * BALB/c
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| MP:0006138 | congestive heart failure | "the heart is unable to adequately pump blood throughout the body" [ncbi:Matthew Mailman, NCBI request, smb:Susan M Bello, Mouse Genome Informatics Curator] |
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Allelic Composition: Mycntm1Jrt/Mycntm1Par
Genetic Background: involves: 129S2/SvPas * C57BL/6J
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| MP:0006279 | abnormal limb development | "anomaly in the formation of the limbs" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"] |
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Allelic Composition: Mycntm1Knd/Mycntm1Knd
Genetic Background: involves: 129P2/OlaHsd * BALB/c
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| MP:0006382 | abnormal lung epithelium morphology | "any structural anomaly of the epithelial layer of the lung" [MGI:rbabiuk "Randall Babiuk, Mouse Genome Informatics Curator", MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"] |
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Allelic Composition: Mycntm1Psk/Mycntm1Psk,Tg(Sftpc-cre)1Blh/0
Genetic Background: involves: 129 * C57BL/6 * ICR
Allelic Composition: Mycntm1Psk/Mycn+,Tg(Sftpc-cre)1Blh/0
Genetic Background: involves: 129 * C57BL/6 * ICR
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| MP:0006408 | dorsal root ganglion hypoplasia | "underdevelopment or reduced size, usually due to a reduced cell number, of a dorsal root ganglion or ganglia" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator", MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"] |
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Allelic Composition: Pax6Sey/Pax6Sey
Genetic Background: involves: C57BL/6J * DBA/2J
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| MP:0008458 | abnormal cortical ventricular zone morphology | "any structural anomaly of a transient region of the developing cerebral cortex that contains migrating neurons, radial glial cells, and a large population of cycling multipotent neural stem cells that generate newborn neurons" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Mycntm1Psk/Mycntm1Psk,Tg(Nes-cre)1Kln/0
Genetic Background: involves: 129 * C57BL/6 * SJL
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| MP:0008487 | abnormal mesonephros morphology | "any structural anomaly of the excretory organ of the embryo, collective Wolffian tubules, which forms the urogenital fold from which the reproductive organs develop" [MESH:A16.254.500] |
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Allelic Composition: Pax6Sey/Pax6Sey
Genetic Background: involves: C57BL/6J * DBA/2J
Allelic Composition: Mycntm1Par/Mycntm1Par
Genetic Background: involves: 129S2/SvPas * C57BL/6J
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| MP:0008770 | decreased survivor rate | "a smaller percentage of organisms than expected survive to adulthood and have a lifespan similar to controls" [MGI:llw2 "Linda Washburn, Mouse Genome Informatics Curator"] |
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Allelic Composition: Mycntm1Psk/Mycn+,Tg(Sftpc-cre)1Blh/0
Genetic Background: involves: 129 * C57BL/6 * ICR
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| MP:0008825 | abnormal cardiac epithelial to mesenchymal transition | "anomaly in the process by which endocardial cells of the atrioventricular canal lose their epithelial characteristics, delaminante from the endocardial sheet, become migratory and invade the cardiac jelly, and develop mesenchymal characteristics eventaully forming the endocardial cushions reqired for septum and atrioventricular valve formation" [PMID:17303760] |
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Allelic Composition: Pax6Sey/Pax6Sey
Genetic Background: involves: C57BL/6J * DBA/2J
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| MP:0008924 | decreased granule neuron number | "reduction in the number of the small neurons of the granule cell layer that send parallel fibers to the upper molecular layer, where they synapse with Purkinje cell dendrites" [ISBN:0838580343 "Kandel ER, et al. Principles of Neural Science, 3rd edition"] |
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Allelic Composition: Mycntm1.1Mlit/Mycntm1.1Mlit,Tg(CAG-tTS)1Mlit/0
Genetic Background: involves: 129S6/SvEvTac * C57BL/6 * C57BL/6J
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| MP:0009937 | abnormal neuron differentiation | "abnormal growth or development of the cells of the nervous system that receive, conduct, and transmit impulses" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Mycntm1Psk/Mycntm1Psk,Tg(Nes-cre)1Kln/0
Genetic Background: involves: 129 * C57BL/6 * SJL
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| MP:0010432 | common ventricle | "the presence of only one working lower chamber in the heart, usually with a virtual absence of the ventricular septum and usually present in conjunction with double inlet left or right ventricle" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Mycntm1Knd/Mycntm1Knd
Genetic Background: involves: 129P2/OlaHsd * BALB/c
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| MP:0010811 | decreased type II pneumocyte number | "reduced number of the granular and roughly cuboidal cells typically found at the alveolar-septal junction that modulate the fluid surrounding the alveolar epithelium by secreting and recycling surfactants, and also contribute to tissue repair and can differentiate after injury into a type I pneumocyte; type II cells cover a much smaller surface area than type I cells (less than 5 percent), but are much more numerous and contain lamellar bodies on the apical surface where surfactant is stored" [ISBN:0412046911, MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator", PMID:8540632] |
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Allelic Composition: Mycntm1Psk/Mycntm1Psk,Tg(Sftpc-cre)1Blh/0
Genetic Background: involves: 129 * C57BL/6 * ICR
Allelic Composition: Mycntm1Psk/Mycn+,Tg(Sftpc-cre)1Blh/0
Genetic Background: involves: 129 * C57BL/6 * ICR
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| MP:0010816 | decreased type I pneumocyte number | "reduced number of the flattened, branched squamous cells that covers more than 98 percent of the alveolar surface, and have thin (50-100 nm) cytoplasmic extensions to form the air-blood barrier essential for normal gas exchange" [PMID:20054144] |
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Allelic Composition: Mycntm1Psk/Mycntm1Psk,Tg(Sftpc-cre)1Blh/0
Genetic Background: involves: 129 * C57BL/6 * ICR
Allelic Composition: Mycntm1Psk/Mycn+,Tg(Sftpc-cre)1Blh/0
Genetic Background: involves: 129 * C57BL/6 * ICR
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| MP:0010986 | abnormal mesonephric mesenchyme morphology | "any structural anomaly of the embryonic connective tissue made up of loosely aggregated mesenchymal cells, supported by interlaminar jelly, in the developing mesonephros" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Mycntm1Par/Mycntm1Par
Genetic Background: involves: 129S2/SvPas * C57BL/6J
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| MP:0011024 | abnormal branching involved in lung morphogenesis | "anomaly in the process in which the branched structure of the respiratory airway tree is generated and organized" [MGI:csmith] |
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Allelic Composition: Mycntm1Psk/Mycntm1Psk,Tg(Sftpc-cre)1Blh/0
Genetic Background: involves: 129 * C57BL/6 * ICR
Allelic Composition: Mycntm1Psk/Mycn+,Tg(Sftpc-cre)1Blh/0
Genetic Background: involves: 129 * C57BL/6 * ICR
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| MP:0011028 | impaired branching involved in bronchus morphogenesis | |
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Allelic Composition: Mycntm1Knd/Mycntm1Knd
Genetic Background: involves: 129P2/OlaHsd * BALB/c
Allelic Composition: Mycntm1Par/Mycntm1Par
Genetic Background: involves: 129S2/SvPas * C57BL/6J
Allelic Composition: Mycntm1Jrt/Mycntm1Par
Genetic Background: involves: 129S2/SvPas * C57BL/6J
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| MP:0011086 | partial postnatal lethality | "the appearance of lower than Mendelian ratios of organisms of a given genotype due to death of some, but not all of the organisms anytime between the neonatal period and weaning age (Mus: P1 to approximately 3 weeks of age)" [MGI:csmith] |
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Allelic Composition: Myogtm3Whk/Myogtm3Whk,Tg(CAG-cre/Esr1*)5Amc/0
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6 * CBA
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| MP:0011087 | complete neonatal lethality | "death of all organisms of a given genotype in a population within the neonatal period after birth (Mus: P0)" [MGI:csmith] |
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Allelic Composition: Pax6Sey/Pax6Sey
Genetic Background: involves: C57BL/6J * DBA/2J
Allelic Composition: Mycntm1Nagy/Mycntm2.1Nagy
Genetic Background: involves: 129S1/Sv * 129X1/SvJ
Allelic Composition: Mycntm1Psk/Mycntm1Psk,Tg(Sftpc-cre)1Blh/0
Genetic Background: involves: 129 * C57BL/6 * ICR
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| MP:0011088 | partial neonatal lethality | "the appearance of lower than Mendelian ratios of organisms of a given genotype due to death of some, but not all of the organisms within the neonatal period after birth (Mus: P0)" [MGI:csmith] |
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Allelic Composition: Mycntm1Psk/Mycn+,Tg(Sftpc-cre)1Blh/0
Genetic Background: involves: 129 * C57BL/6 * ICR
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| MP:0011091 | complete prenatal lethality | "death of all organisms of a given genotype in a population between fertilization and birth (Mus: approximately E18.5)" [MGI:csmith] |
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Allelic Composition: Thrbtm1Df/Thrbtm1Df
Genetic Background: involves: 129S1/Sv * C57BL/6J * FVB/NJ
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| MP:0011098 | complete embryonic lethality during organogenesis | "death of all organisms of a given genotype in a population between embryo turning and the completion of organogenesis (Mus: E9 to less than E14)" [MGI:csmith] |
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Allelic Composition: Pax6Sey/Pax6Sey
Genetic Background: involves: C57BL/6J * DBA/2J
Allelic Composition: Mycntm1Knd/Mycntm1Knd
Genetic Background: involves: 129P2/OlaHsd * BALB/c
Allelic Composition: Mycntm2Nagy/Mycntm2Nagy
Genetic Background: involves: 129S1/Sv * 129X1/SvJ
Allelic Composition: Mycntm2.1Nagy/Mycntm2.1Nagy
Genetic Background: involves: 129S1/Sv * 129X1/SvJ
Allelic Composition: Mycntm1Par/Mycntm1Par
Genetic Background: involves: 129S2/SvPas * C57BL/6J
Allelic Composition: Mycntm1Jrt/Mycntm1Par
Genetic Background: involves: 129S2/SvPas * C57BL/6J
Allelic Composition: Mycntm1.1Mlit/Mycntm1.1Mlit,Tg(CAG-tTS)1Mlit/0
Genetic Background: involves: 129S6/SvEvTac * C57BL/6 * C57BL/6J
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| MP:0011412 | gonadal ridge hypoplasia | "underdevelopment or reduced size of the elevation of thickened mesothelium and underlying mesenchyme found on the ventromedial border of the embryonic mesonephros, usually due to reduced cell number; normally, primordial germ cells become embedded in it, establishing it as the primordium of the testis or ovary" [MGI:anna] |
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Allelic Composition: Mycntm1Par/Mycntm1Par
Genetic Background: involves: 129S2/SvPas * C57BL/6J
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| MP:0011875 | absent stomach | "absence of the sac-like structure of the digestive canal between the esophagus and the small intestine" [MGI:Colin_McKerlie] |
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Allelic Composition: Mycntm1Par/Mycntm1Par
Genetic Background: involves: 129S2/SvPas * C57BL/6J
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| MP:0012703 | decreased embryonic neuroepithelium thickness | "reduced width of the epithelial cell layer that lines the neural tube and develops into the nervous system and into the neural crest cells" [MGI:anna] |
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Allelic Composition: Mycntm1Psk/Mycntm1Psk,Tg(Nes-cre)1Kln/0
Genetic Background: involves: 129 * C57BL/6 * SJL
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| MP:0013267 | first pharyngeal arch hypoplasia | "underdevelopment or reduced size of the first pharyngeal arch, usually due to reduced cell number" [MGI:anna] |
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Allelic Composition: Mycntm1Par/Mycntm1Par
Genetic Background: involves: 129S2/SvPas * C57BL/6J
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