ENSMUSG00000052922


Mus musculus

Features
Gene ID: ENSMUSG00000052922
  
Biological name :Bpi
  
Synonyms : Bpi / Mus musculus bactericidal permeablility increasing protein (Bpi), transcript variant 2, mRNA. / Q67E05
  
Possible biological names infered from orthology : bactericidal/permeability-increasing protein / P17213
  
Species: Mus musculus
  
Chr. number: 2
Strand: 1
Band: H1
Gene start: 158258094
Gene end: 158284531
  
Corresponding Affymetrix probe sets: 10478031 (MoGene1.0st)   
  
Cross references: Ensembl peptide - ENSMUSP00000067837
Ensembl peptide - ENSMUSP00000105125
Ensembl peptide - ENSMUSP00000105126
NCBI entrez gene - 329547     See in Manteia.
MGI - MGI:3045315
RefSeq - XM_017319056
RefSeq - NM_001356542
RefSeq - NM_177850
RefSeq - XM_006499789
RefSeq - XM_017319055
RefSeq Peptide - NP_001343471
RefSeq Peptide - NP_808518
swissprot - Q67E05
Ensembl - ENSMUSG00000052922
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ENSGALG00000006756Gallus gallus
 BPIENSG00000101425Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Lbp / Q61805 / Lipopolysaccharide-binding protein / P18428*ENSMUSG0000001602437
Pltp / P55065 / phospholipid transfer protein / P55058*ENSMUSG0000001775425
Bpifc / BPI fold containing family C / Q8NFQ6*ENSMUSG0000005010823


Protein motifs (from Interpro)
Interpro ID Name
 IPR001124  Lipid-binding serum glycoprotein, C-terminal
 IPR017942  Lipid-binding serum glycoprotein, N-terminal
 IPR017943  Bactericidal permeability-increasing protein, alpha/beta domain superfamily
 IPR030181  Bactericidal permeability-increasing protein
 IPR030675  Lipid binding protein BPI/LBP
 IPR032942  BPI/LBP/Plunc family


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006955 immune response IEA
 biological_processGO:0032715 negative regulation of interleukin-6 production IEA
 biological_processGO:0032717 negative regulation of interleukin-8 production IEA
 biological_processGO:0032720 negative regulation of tumor necrosis factor production IEA
 biological_processGO:0042742 defense response to bacterium IEA
 biological_processGO:0043031 negative regulation of macrophage activation IEA
 biological_processGO:0050829 defense response to Gram-negative bacterium IEA
 cellular_componentGO:0005576 extracellular region IEA
 cellular_componentGO:0005615 extracellular space IEA
 cellular_componentGO:0005737 cytoplasm IDA
 cellular_componentGO:0016020 membrane IEA
 molecular_functionGO:0001530 lipopolysaccharide binding ISO
 molecular_functionGO:0008289 lipid binding IEA


Pathways (from Reactome)
Pathway description
Toll Like Receptor 4 (TLR4) Cascade
Neutrophil degranulation
Antimicrobial peptides


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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