ENSGALG00000006756


Gallus gallus

Features
Gene ID: ENSGALG00000006756
  
Biological name :
  
Synonyms :
  
Possible biological names infered from orthology : bactericidal/permeability-increasing protein / BPI / LBP / lipopolysaccharide binding protein / Mus musculus bactericidal permeablility increasing protein (Bpi), transcript variant 2, mRNA. / P17213 / P18428 / Q61805 / Q67E05
  
Species: Gallus gallus
  
Chr. number: 20
Strand: -1
Band:
Gene start: 10542586
Gene end: 10549724
  
Corresponding Affymetrix probe sets: Gga.11658.1.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000010903
NCBI entrez gene - 419293     See in Manteia.
RefSeq - XM_004947186
RefSeq - XM_417465
swissprot - F1NXX9
Ensembl - ENSGALG00000006756
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 BPIENSG00000101425Homo sapiens
 LBPENSG00000129988Homo sapiens
 BpiENSMUSG00000052922Mus musculus
 LbpENSMUSG00000016024Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
ENSGALG0000002102528
BPIFC* / Q8NFQ6* / BPI fold containing family C*ENSGALG0000004526027
BPIFC* / Q8NFQ6* / BPI fold containing family C*ENSGALG0000003947927
PLTP / phospholipid transfer protein precursor / P55058* / P55065* / phospholipid transfer protein*ENSGALG0000003668622


Protein motifs (from Interpro)
Interpro ID Name
 IPR001124  Lipid-binding serum glycoprotein, C-terminal
 IPR017942  Lipid-binding serum glycoprotein, N-terminal
 IPR017943  Bactericidal permeability-increasing protein, alpha/beta domain superfamily
 IPR030180  Lipopolysaccharide-binding protein
 IPR030675  Lipid binding protein BPI/LBP
 IPR032942  BPI/LBP/Plunc family


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006955 immune response IEA
 biological_processGO:0050829 defense response to Gram-negative bacterium IEA
 cellular_componentGO:0005615 extracellular space IEA
 molecular_functionGO:0001530 lipopolysaccharide binding IEA
 molecular_functionGO:0008289 lipid binding IEA


Pathways (from Reactome)
Pathway description
Toll Like Receptor 4 (TLR4) Cascade
Transfer of LPS from LBP carrier to CD14
Regulation of TLR by endogenous ligand
Neutrophil degranulation
Antimicrobial peptides


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSGALG00000039140 CD14 / monocyte differentiation antigen CD14 precursor / P10810* / P08571* / CD14 molecule* / Monocyte differentiation antigen CD14 *  / reaction






 

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