ENSGALG00000039140


Gallus gallus

Features
Gene ID: ENSGALG00000039140
  
Biological name :CD14
  
Synonyms : CD14 / monocyte differentiation antigen CD14 precursor
  
Possible biological names infered from orthology : CD14 molecule / Monocyte differentiation antigen CD14 / P08571 / P10810
  
Species: Gallus gallus
  
Chr. number: 13
Strand: 1
Band:
Gene start: 954498
Gene end: 955895
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSGALP00000052840
NCBI entrez gene - 100194427     See in Manteia.
RefSeq - NM_001139478
RefSeq - XM_015293508
RefSeq Peptide - NP_001132950
swissprot - A0A1D5PJ49
Ensembl - ENSGALG00000039140
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 CD14ENSG00000170458Homo sapiens
 Cd14ENSMUSG00000051439Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR001611  Leucine-rich repeat
 IPR003591  Leucine-rich repeat, typical subtype
 IPR032675  Leucine-rich repeat domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA


Pathways (from Reactome)
Pathway description
via Death Receptors in the presence of ligand
Toll Like Receptor 4 (TLR4) Cascade
Transfer of LPS from LBP carrier to CD14
MyD88-independent TLR4 cascade
TRIF-mediated programmed cell death
Regulation of TLR by endogenous ligand
Neutrophil degranulation
Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon
IKK complex recruitment mediated by RIP1
TRAF6-mediated induction of TAK1 complex within TLR4 complex


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSGALG00000003595 SARM1 / sterile alpha and TIR motif containing 1 / Q6PDS3* / Q6SZW1* / Sterile alpha and TIR motif-containing protein 1 *  / complex / reaction
 ENSGALG00000006756 LBP* / BPI* / Q61805* / P18428* / Q67E05* / P17213* / lipopolysaccharide binding protein* / bactericidal/permeability-increasing protein* / Mus musculus bactericidal permeablility increasin...  / reaction
 ENSGALG00000016284 TAB3 / TGF-beta activated kinase 1 and MAP3K7 binding protein 3 / Q571K4* / Q8N5C8* / TGF-beta activated kinase 1/MAP3K7 binding protein 3*  / reaction / complex
 ENSGALG00000012356 TAB2 / TGF-beta activated kinase 1/MAP3K7 binding protein 2 / Q99K90* / Q9NYJ8* / TGF-beta-activated kinase 1 and MAP3K7-binding protein 2 *  / complex / reaction
 ENSGALG00000015596 MAP3K7 / mitogen-activated protein kinase kinase kinase 7 / O43318* / Q62073*  / complex / reaction
 ENSGALG00000011131 TANK / TRAF family member associated NFKB activator / P70347* / Q92844* / Mus musculus TRAF family member-associated Nf-kappa B activator (Tank), transcript variant 4, mRNA.*  / reaction / complex
 ENSGALG00000012150 TAB1 / TGF-beta activated kinase 1 (MAP3K7) binding protein 1 / Q15750* / Q8CF89* / TGF-beta-activated kinase 1 and MAP3K7-binding protein 1 *  / reaction / complex
 ENSGALG00000009840 TBK1 / TANK binding kinase 1 / Q9UHD2* / Q9WUN2*  / complex / reaction
 ENSGALG00000026850 TICAM1 / TIR domain-containing adapter molecule 1 / Q80UF7* / Q8IUC6* / toll like receptor adaptor molecule 1*  / reaction / complex
 ENSGALG00000037716 UBA52 / ubiquitin A-52 residue ribosomal protein fusion product 1 / P62984* / P62987* / Gm5239* / Gm11808* / predicted gene 11808*  / complex / reaction
 ENSGALG00000036790 P79781 / RPS27A / Ubiquitin-40S ribosomal protein S27a Ubiquitin 40S ribosomal protein S27a / P62983* / P62979* / AL136454.1* / ribosomal protein S27a*  / complex / reaction
 ENSGALG00000012827 RIPK1 / receptor interacting serine/threonine kinase 1 / Q13546* / Q60855* / Receptor-interacting serine/threonine-protein kinase 1 *  / reaction / complex
 ENSGALG00000007932 TRAF6 / TNF receptor associated factor 6 / P70196* / Q9Y4K3*  / complex / reaction
 ENSGALG00000032701 LY96 / lymphocyte antigen 96 / Q9JHF9* / Q9Y6Y9*  / complex / reaction
 ENSGALG00000011389 TRAF3 / TNF receptor associated factor 3 / Q13114* / Q60803*  / complex / reaction
 ENSGALG00000007625 FADD / Fas associated via death domain / Q13158* / Q61160* / FAS-associated death domain protein *  / reaction / complex
 ENSGALG00000039140 CD14 / monocyte differentiation antigen CD14 precursor / P10810* / P08571* / CD14 molecule* / Monocyte differentiation antigen CD14 *  / complex






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr