ENSGALG00000032701


Gallus gallus

Features
Gene ID: ENSGALG00000032701
  
Biological name :LY96
  
Synonyms : LY96 / lymphocyte antigen 96
  
Possible biological names infered from orthology : Q9JHF9 / Q9Y6Y9
  
Species: Gallus gallus
  
Chr. number: 2
Strand: 1
Band:
Gene start: 118468953
Gene end: 118475495
  
Corresponding Affymetrix probe sets: Gga.5743.1.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000045949
NCBI entrez gene - 420189     See in Manteia.
RefSeq - XM_004939913
RefSeq - XM_418301
swissprot - A0A1D5NZX9
Ensembl - ENSGALG00000032701
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 LY96ENSG00000154589Homo sapiens
 Ly96ENSMUSG00000025779Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR003172  MD-2-related lipid-recognition domain
 IPR014756  Immunoglobulin E-set


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0031663 lipopolysaccharide-mediated signaling pathway IEA
 biological_processGO:0031666 positive regulation of lipopolysaccharide-mediated signaling pathway IEA
 biological_processGO:0032496 response to lipopolysaccharide IEA
 biological_processGO:0032497 detection of lipopolysaccharide IEA
 biological_processGO:0032760 positive regulation of tumor necrosis factor production IEA
 biological_processGO:0034142 toll-like receptor 4 signaling pathway IEA
 biological_processGO:0071222 cellular response to lipopolysaccharide IEA
 cellular_componentGO:0031226 intrinsic component of plasma membrane IEA
 cellular_componentGO:0046696 lipopolysaccharide receptor complex IEA
 molecular_functionGO:0001875 lipopolysaccharide receptor activity IEA


Pathways (from Reactome)
Pathway description
via Death Receptors in the presence of ligand
Toll Like Receptor 4 (TLR4) Cascade
MyD88-independent TLR4 cascade
TRIF-mediated programmed cell death
Regulation of TLR by endogenous ligand
Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon
IKK complex recruitment mediated by RIP1
TRAF6-mediated induction of TAK1 complex within TLR4 complex


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSGALG00000002496 SFTPA1 / Q8IWL2* / SFTPA2* / Q8IWL1* / surfactant protein A1* / surfactant protein A2* / surfactant associated protein A1*  / complex / reaction
 ENSGALG00000002503 SFTPA2 / Q8IWL2* / SFTPA1* / Q8IWL1* / surfactant protein A1* / surfactant protein A2* / surfactant associated protein A1*  / reaction / complex
 ENSGALG00000003595 SARM1 / sterile alpha and TIR motif containing 1 / Q6PDS3* / Q6SZW1* / Sterile alpha and TIR motif-containing protein 1 *  / complex / reaction
 ENSGALG00000016284 TAB3 / TGF-beta activated kinase 1 and MAP3K7 binding protein 3 / Q571K4* / Q8N5C8* / TGF-beta activated kinase 1/MAP3K7 binding protein 3*  / complex / reaction
 ENSGALG00000009268 FGG / fibrinogen gamma chain / P02679* / Q8VCM7*  / reaction / complex
 ENSGALG00000012356 TAB2 / TGF-beta activated kinase 1/MAP3K7 binding protein 2 / Q99K90* / Q9NYJ8* / TGF-beta-activated kinase 1 and MAP3K7-binding protein 2 *  / reaction / complex
 ENSGALG00000015596 MAP3K7 / mitogen-activated protein kinase kinase kinase 7 / O43318* / Q62073*  / reaction / complex
 ENSGALG00000011131 TANK / TRAF family member associated NFKB activator / P70347* / Q92844* / Mus musculus TRAF family member-associated Nf-kappa B activator (Tank), transcript variant 4, mRNA.*  / reaction / complex
 ENSGALG00000012150 TAB1 / TGF-beta activated kinase 1 (MAP3K7) binding protein 1 / Q15750* / Q8CF89* / TGF-beta-activated kinase 1 and MAP3K7-binding protein 1 *  / reaction / complex
 ENSGALG00000009840 TBK1 / TANK binding kinase 1 / Q9UHD2* / Q9WUN2*  / complex / reaction
 ENSGALG00000026850 TICAM1 / TIR domain-containing adapter molecule 1 / Q80UF7* / Q8IUC6* / toll like receptor adaptor molecule 1*  / reaction / complex
 ENSGALG00000037716 UBA52 / ubiquitin A-52 residue ribosomal protein fusion product 1 / P62984* / P62987* / Gm5239* / Gm11808* / predicted gene 11808*  / complex / reaction
 ENSGALG00000009262 FGB / fibrinogen beta chain / P02675* / Q8K0E8* / Fibrinogen beta chain Fibrinopeptide B Fibrinogen beta chain*  / complex / reaction
 ENSGALG00000036790 P79781 / RPS27A / Ubiquitin-40S ribosomal protein S27a Ubiquitin 40S ribosomal protein S27a / P62983* / P62979* / AL136454.1* / ribosomal protein S27a*  / complex / reaction
 ENSGALG00000039140 CD14 / monocyte differentiation antigen CD14 precursor / P10810* / P08571* / CD14 molecule* / Monocyte differentiation antigen CD14 *  / complex / reaction
 ENSGALG00000012827 RIPK1 / receptor interacting serine/threonine kinase 1 / Q13546* / Q60855* / Receptor-interacting serine/threonine-protein kinase 1 *  / complex / reaction
 ENSGALG00000007932 TRAF6 / TNF receptor associated factor 6 / P70196* / Q9Y4K3*  / reaction / complex
 ENSGALG00000032701 LY96 / lymphocyte antigen 96 / Q9JHF9* / Q9Y6Y9*  / complex / reaction
 ENSGALG00000011389 TRAF3 / TNF receptor associated factor 3 / Q13114* / Q60803*  / reaction / complex
 ENSGALG00000042875 HMGB1 / Q9YH06 / High mobility group protein B1 / P09429* / P63158* / high mobility group box 1*  / reaction / complex
 ENSGALG00000007625 FADD / Fas associated via death domain / Q13158* / Q61160* / FAS-associated death domain protein *  / reaction / complex
 ENSGALG00000034458 S100A1 / S100 calcium binding protein A1 / P23297*  / reaction / complex






 

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