ENSGALG00000011131


Gallus gallus

Features
Gene ID: ENSGALG00000011131
  
Biological name :TANK
  
Synonyms : TANK / TRAF family member associated NFKB activator
  
Possible biological names infered from orthology : Mus musculus TRAF family member-associated Nf-kappa B activator (Tank), transcript variant 4, mRNA. / P70347 / Q92844
  
Species: Gallus gallus
  
Chr. number: 7
Strand: -1
Band:
Gene start: 21566139
Gene end: 21593731
  
Corresponding Affymetrix probe sets: Gga.11608.1.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000032485
NCBI entrez gene - 424190     See in Manteia.
RefSeq - NM_001277871
RefSeq - XM_015289646
RefSeq Peptide - NP_001264800
swissprot - E1C5I0
Ensembl - ENSGALG00000011131
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 tankENSDARG00000067723Danio rerio
 TANKENSG00000136560Homo sapiens
 TankENSMUSG00000064289Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR024581  Tbk1/Ikki binding domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006508 proteolysis IEA
 biological_processGO:0006974 cellular response to DNA damage stimulus IEA
 biological_processGO:0007249 I-kappaB kinase/NF-kappaB signaling IEA
 biological_processGO:0043124 negative regulation of I-kappaB kinase/NF-kappaB signaling IEA
 biological_processGO:0071347 cellular response to interleukin-1 IEA
 biological_processGO:0071356 cellular response to tumor necrosis factor IEA
 biological_processGO:0071479 cellular response to ionizing radiation IEA
 biological_processGO:1903003 positive regulation of protein deubiquitination IEA
 biological_processGO:2000158 positive regulation of ubiquitin-specific protease activity IEA
 cellular_componentGO:0005829 cytosol IEA
 cellular_componentGO:0032991 protein-containing complex IEA
 molecular_functionGO:0004843 thiol-dependent ubiquitin-specific protease activity IEA
 molecular_functionGO:0031625 ubiquitin protein ligase binding IEA
 molecular_functionGO:0035800 deubiquitinase activator activity IEA


Pathways (from Reactome)
Pathway description
TRAF mediated activation of IRF
Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSGALG00000011389 TRAF3 / TNF receptor associated factor 3 / Q13114* / Q60803*  / complex / reaction
 ENSGALG00000026850 TICAM1 / TIR domain-containing adapter molecule 1 / Q80UF7* / Q8IUC6* / toll like receptor adaptor molecule 1*  / reaction / complex
 ENSGALG00000032701 LY96 / lymphocyte antigen 96 / Q9JHF9* / Q9Y6Y9*  / reaction / complex
 ENSGALG00000011131 TANK / TRAF family member associated NFKB activator / P70347* / Q92844* / Mus musculus TRAF family member-associated Nf-kappa B activator (Tank), transcript variant 4, mRNA.*  / reaction / complex
 ENSGALG00000009840 TBK1 / TANK binding kinase 1 / Q9UHD2* / Q9WUN2*  / reaction / complex
 ENSGALG00000039140 CD14 / monocyte differentiation antigen CD14 precursor / P10810* / P08571* / CD14 molecule* / Monocyte differentiation antigen CD14 *  / reaction / complex






 

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