| MP:0000609 | abnormal liver physiology | "aberrant function of this bile-secreting exocrine gland, which is important for detoxification; for fat, carbohydrate, and protein metabolism; and for glycogen storage " [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
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Allelic Composition: Cry2tm1.1Yf/Cry2tm1.1Yf
Genetic Background: B6J.Cg-Cry2tm1.1Yf
|
| MP:0000619 | salivary gland epithelial hyperplasia | "increased cell number in the epithelium of the salivary gland" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:63764] |
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Allelic Composition: Ap3b1tm1Sms/Ap3b1tm1Sms
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6
Allelic Composition: Per2tm1Ccl/Per2tm1Ccl
Genetic Background: involves: 129 * C57BL/6
|
| MP:0001259 | abnormal body weight | "anomaly in average weight compared to the norm" [cwg:Carroll W. Goldsmith, Mouse Genome Informatics Curator] |
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Allelic Composition: Ap3b1tm1Sms/Ap3b1tm1Sms
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6
|
| MP:0001260 | increased body weight | "greater than normal average weight " [J:33400] |
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Allelic Composition: Ap3b1tm1Sms/Ap3b1tm1Sms
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6
|
| MP:0001325 | abnormal retina morphology | "structural or developmental anomaly of the thin layer of neural tissue lining the back of the eyeball which contains visual receptors " [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator] |
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Allelic Composition: Per2tm1Drw/Per2tm1Drw
Genetic Background: B6.129-Per2tm1Drw/J
|
| MP:0001385 | pup cannibalization | "the killing and eating of newborn mice by the mother; can be a normal response if the mother does not recognize the pups as her own" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
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Allelic Composition: Ap3b1tm1Sms/Ap3b1tm1Sms
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6
|
| MP:0001432 | abnormal food preference | "the desire to eat more or less food than average, or to eat unusual foods" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
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Allelic Composition: Ap3b1tm1Sms/Ap3b1tm1Sms
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6
|
| MP:0001501 | abnormal sleep pattern | "deviation from the normal wake/sleep cycle" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
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Allelic Composition: Per1tm1Drw/Per1tm1Drw,Per3tm1Drw/Per3tm1Drw
Genetic Background: involves: 129S4/SvJae
Allelic Composition: Per2tm1Drw/Per2tm1Drw
Genetic Background: involves: 129/Sv
|
| MP:0001614 | abnormal vasculature | "anomalies in the structure of development of the network of tubes that carries blood through the body" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
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Allelic Composition: Gtpbp2nmf205/Gtpbp2nmf205,n-TRtct5m1J/n-TRtct5+
Genetic Background: involves: C57BL/6J * CBA/J
|
| MP:0001658 | increased mortality induced by gamma-irradiation | "greater sensitivity to doses of ionizing radiation" [J:51834] |
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Allelic Composition: Ap3b1tm1Sms/Ap3b1tm1Sms
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6
|
| MP:0001792 | impaired wound healing | "reduced ability or inability to self-repair and close wounds" [J:65302, cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator] |
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Allelic Composition: Arntltm1Bra/Arntltm1Bra
Genetic Background: involves: 129/Sv * C57BL/6
|
| MP:0001923 | reduced female fertility | "reduced ability of female to produce live offspring" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:60409] |
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Allelic Composition: Ap3b1tm1Sms/Ap3b1tm1Sms
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6
|
| MP:0001935 | reduced litter size | "fewer live born pups in a litter compared to average" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
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Allelic Composition: Ap3b1tm1Sms/Ap3b1tm1Sms
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6
|
| MP:0002075 | abnormal coat color | "irregular or unusual pigmentation pattern of the hair in relation to control animals" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
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Allelic Composition: Otud7btm1(NCOM)Cmhd/Otud7btm1(NCOM)Cmhd
Genetic Background: C57BL/6N-Otud7btm1(NCOM)Cmhd/Tcp
|
| MP:0002083 | premature death | "death after 3 weeks of age, but before normal life span" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
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Allelic Composition: Ap3b1tm1Sms/Ap3b1tm1Sms
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6
|
| MP:0002113 | abnormal skeleton development | "anomalous differentiation or remodeling of bone tissue resulting in morphological abnormality" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
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Allelic Composition: Arntltm1Bra/Arntltm1Bra
Genetic Background: involves: 129/Sv * C57BL/6
Allelic Composition: Per1tm1Brd/Per1tm1Brd,Per2tm1Brd/Per2tm1.1Kry,Tg(Col1a1-cre)1Kry/0
Genetic Background: involves: 129S7/SvEvBrd * FVB
|
| MP:0002169 | no phenotype detected | "normal, viable and fertile appearance and behavior; indistinguishable from controls" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
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Allelic Composition: Grk1tm1Citb/Grk1tm1Citb,Nrltm1Asw/Nrltm1Asw
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6J
|
| MP:0002398 | abnormal bone marrow cell morphology/development | "anomalous structure or formation of the cells found in the bone marrow" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator] |
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Allelic Composition: Arntltm1Bra/Arntltm1Bra
Genetic Background: involves: 129/Sv * C57BL/6
Allelic Composition: Per2tm1Drw/Per2tm1Drw
Genetic Background: B6.129-Per2tm1Drw/J
|
| MP:0002717 | abnormal preputial gland morphology | "anomalous structure of the sebaceous glands of the corona and neck of the glans penis" [Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
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Allelic Composition: Ap3b1tm1Sms/Ap3b1tm1Sms
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6
|
| MP:0002792 | abnormal retinal vascularization | "malformation or disorganization of the blood vessels supplying the retina" [cml:Cathleen M. Lutz , Mouse Genome Informatics Curator] |
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Allelic Composition: Per2tm1Drw/Per2tm1Drw
Genetic Background: B6.129-Per2tm1Drw/J
|
| MP:0002896 | abnormal bone mineralization | "defect in the process by which minerals are deposited into bone" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
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Allelic Composition: Otud7btm1(NCOM)Cmhd/Otud7btm1(NCOM)Cmhd
Genetic Background: C57BL/6N-Otud7btm1(NCOM)Cmhd/Tcp
|
| MP:0002968 | increased circulating alkaline phosphatase level | "elevated activity of this enzyme, which hydrolyzes orthophosphoric monoesters, found in the blood" [RGD:Rat Genome Database submission, Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8] |
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Allelic Composition: Otud7btm1(NCOM)Cmhd/Otud7btm1(NCOM)Cmhd
Genetic Background: C57BL/6N-Otud7btm1(NCOM)Cmhd/Tcp
|
| MP:0003207 | decreased sensitivity to gamma-irradiation | "decreased incidence of cell death following high levels of gamma-irradiation" [J:92917, smb:Susan M Bello, Mouse Genome Informatics Curator] |
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Allelic Composition: Ap3b1tm1Sms/Ap3b1tm1Sms
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6
Allelic Composition: Per2tm1Ccl/Per2tm1Ccl
Genetic Background: involves: 129 * C57BL/6
|
| MP:0003632 | abnormal nervous system morphology | |
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Allelic Composition: Per2tm1Drw/Per2tm1Drw
Genetic Background: B6.129-Per2tm1Drw/J
|
| MP:0004500 | increased incidence of ionizing radiation-induced tumors | "higher than normal frequency of tumor incidence induced by radiation in which the individual particle or photon carries sufficient energy to completely remove an electron from its orbit; common types of this radiation include gamma-rays and X-rays" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"] |
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Allelic Composition: Ap3b1tm1Sms/Ap3b1tm1Sms
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6
|
| MP:0004809 | increased hematopoietic stem cell number | "greater cell count of the multipotent, self-renewing stem cells found in the bone marrow and the fetal liver; these give rise to all the types of both the myeloid and lymphoid cell lineages" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Per2tm1Drw/Per2tm1Drw
Genetic Background: B6.129-Per2tm1Drw/J
|
| MP:0004988 | increased osteoblast cell number | "greater than average number of the bone-forming cells, which normally form an osseous matrix (osteoid) in which they become enclosed as an osteocytes" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Arntltm1Bra/Arntltm1Bra
Genetic Background: involves: 129/Sv * C57BL/6
Allelic Composition: Per1tm1Brd/Per1tm1Brd,Per2tm1Brd/Per2tm1.1Kry,Tg(Col1a1-cre)1Kry/0
Genetic Background: involves: 129S7/SvEvBrd * FVB
|
| MP:0004989 | decreased osteoblast cell number | "reduction in the number of the bone-forming cells, which normally form an osseous matrix (osteoid) in which they become enclosed as an osteocytes" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Cry1tm1Jhjh/Cry1tm1Jhjh,Per2tm1Brd/Per2tm1Brd
Genetic Background: involves: 129P2/OlaHsd * 129S7/SvEvBrd * C57BL/6
|
| MP:0004994 | abnormal brain wave pattern | "any anomaly in the standard pattern of rhythmic and rapid fluctuation of electrical potential between parts of the brain, often visualized on an electroencephalogram (EEG); the pattern is often measured to diagnose neurological conditions such as seizure disorders (epilepsy)" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Per1tm1Drw/Per1tm1Drw,Per2tm1Drw/Per2tm1Drw
Genetic Background: involves: 129S4/SvJae
Allelic Composition: Per2Kort/Per2Kort
Genetic Background: C57BL/6J-Per2Kort
|
| MP:0005253 | abnormal eye physiology | "anomalous function and/or activity of the ocular system or any of its parts" [MeSH:National Library of Medicine - Medical Subject Headings , 2003] |
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Allelic Composition: Rgs9tm1(cre)Yql/Rgs9+,Tg(CAG-Ppard*E411P)#Als/0
Genetic Background: B6J.Cg-Rgs9tm1(cre)Yql Tg(CAG-Ppard*E411P)#Als
Allelic Composition: Opn5tm1.1Lan/Opn5tm1.1Yau,Per2tm1Jt/Per2+
Genetic Background: involves: 129S4/SvJaeSor * 129S6/SvEvTac * C57BL/6N * FVB/N
Allelic Composition: Opn5tm1.1Yau/Opn5tm1.1Yau,Per2tm1Jt/Per2+
Genetic Background: involves: 129S6/SvEvTac
|
| MP:0005449 | abnormal food intake | "anomalous total number of calories taken in daily when compared to the norm" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, MeSH:National Library of Medicine - Medical Subject Headings , 2003] |
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Allelic Composition: Ap3b1tm1Sms/Ap3b1tm1Sms
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6
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| MP:0005605 | increased bone mass | "an increase in the total amount of bone tissue contained in the skeleton" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator] |
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Allelic Composition: Arntltm1Bra/Arntltm1Bra
Genetic Background: involves: 129/Sv * C57BL/6
Allelic Composition: Per1tm1Brd/Per1tm1Brd,Per2tm1Brd/Per2tm1.1Kry,Tg(Col1a1-cre)1Kry/0
Genetic Background: involves: 129S7/SvEvBrd * FVB
|
| MP:0005645 | abnormal hypothalamus physiology | "anomalous function of the ventral and medial region of the diencephalon forming the walls of the ventral half of the third ventricle, which is normally involved in the functions of the autonomic (visceral motor) nervous system and, through its vascular link with the anterior lobe of the pituitary gland, in endocrine mechanisms" [Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
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Allelic Composition: Adcy4tm1.1Dek/Adcy4tm1.1Dek,Tg(AQP2-cre)2Dek/0
Genetic Background: involves: C57BL/6 * CBA
|
| MP:0005669 | increased circulating leptin level | "greater than the normal blood concentration of the peptide hormone secreted by white adipocytes and believed to regulate food intake and energy balance" [MeSH:National Library of Medicine - Medical Subject Headings, 2003, J:34751] |
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Allelic Composition: Arntltm1Bra/Arntltm1Bra
Genetic Background: involves: 129/Sv * C57BL/6
|
| MP:0008779 | abnormal maternal behavior | "any response from the mother inconsistent with ability of young to thrive" [MGI:llw2 "Linda Washburn, Mouse Genome Informatics Curator"] |
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Allelic Composition: Ap3b1tm1Sms/Ap3b1tm1Sms
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6
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| MP:0008961 | abnormal basal metabolism | "any anomaly in heat production of an organism at the lowest level of cell chemistry in an inactive, awake, and fasting state" [MESH:E01.370.374.750.100] |
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Allelic Composition: Ap3b1tm1Sms/Ap3b1tm1Sms
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6
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| MP:0008995 | early reproductive senescence | "loss of reproductive capacity occurring at an earlier than expected age" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"] |
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Allelic Composition: Ap3b1tm1Sms/Ap3b1tm1Sms
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6
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| MP:0009006 | prolonged estrous cycle | "increase in the length of the sexual cycle of female animals" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"] |
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Allelic Composition: Ap3b1tm1Sms/Ap3b1tm1Sms
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6
|
| MP:0009009 | absent estrous cycle | "failure of female animals to enter or progress through their sexual cycle" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"] |
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Allelic Composition: Ap3b1tm1Sms/Ap3b1tm1Sms
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6
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| MP:0009661 | abnormal pregnancy | "any anomaly in the process of maintaining a developing embryo or fetus within the female body from conception to birth" [ISBN:0198542771 "Rugh, Roberts, The Mouse: Its Reproduction and Development", MGI:llw2 "Linda Washburn, Mouse Genome Informatics Curator"] |
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Allelic Composition: Ap3b1tm1Sms/Ap3b1tm1Sms
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6
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| MP:0009713 | enhanced conditioned place preference behavior | "increase in the ability of an animal to learn and remember an association between a putative rewarding internal state produced by a xenobiotic or drug with a neutral, unchanging environment" [ISBN:0471316393 "Crawley, JN, What s Wrong with my Mouse: Behavioral Phenotyping of Transgenic and Knockout Mice", MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Ap3b1tm1Sms/Ap3b1tm1Sms
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6
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| MP:0009754 | enhanced behavioral response to cocaine | "increased sensitivity to cocaine resulting in a behavioral response, such as induced hyperactivity or stereotypic behavior, or decreased dosage threshold for the appearance of the behavioral response" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Ap3b1tm1Sms/Ap3b1tm1Sms
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6
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| MP:0010318 | increased salivary gland tumor incidence | "greater than the expected number of neoplams in the salivary gland occurring in a specific population in a given time period" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Per2tm1Ccl/Per2tm1Ccl
Genetic Background: involves: 129 * C57BL/6
|
| MP:0010763 | abnormal hematopoietic stem cell physiology | "any functional anomaly or number of the multipotent, self-renewing stem cells found in the bone marrow and the fetal liver; HSCs give rise to all the types of both the myeloid and lymphoid cell lineages" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Per2tm1Drw/Per2tm1Drw
Genetic Background: B6.129-Per2tm1Drw/J
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| MP:0010875 | increased bone volume | "increased amount of space occupied by bone tissue in the skeleton" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Ap3b1tm1Sms/Ap3b1tm1Sms
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6
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| MP:0011020 | abnormal circadian temperature homeostasis | "any anomaly in the process in which an organism modulates its internal body temperature at different values with a regularity of approximately 24 hours" [GO:0060086] |
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Allelic Composition: Per1tm1Drw/Per1tm1Drw,Per2tm1Drw/Per2tm1Drw
Genetic Background: involves: 129S4/SvJae
Allelic Composition: Per2tm1Drw/Per2tm1Drw
Genetic Background: involves: 129/Sv
|
| MP:0011478 | abnormal urine catecholamine level | "any anomaly in the urinary amount of catecholamines, including adrenaline, noradrenaline and L-dopamine; catecholamines are act as hormones or neurotransmitters and are derived from the amino acid tyrosine" [MGI:csmith] |
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Allelic Composition: Arntltm1Bra/Arntltm1Bra
Genetic Background: involves: 129/Sv * C57BL/6
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| MP:0011903 | decreased hematopoietic stem cell proliferation | "reduction in the expansion rate of a hematopoietic stem cell population by cell division" [MGI:csmith] |
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Allelic Composition: Per2tm1Drw/Per2tm1Drw
Genetic Background: B6.129-Per2tm1Drw/J
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| MP:0012431 | increased lymphoma incidence | "greater than the expected number of neoplasms characterized by a proliferation of malignant lymphocytes in lymphoid tissue in a specific population in a given time period" [http://orcid.org/0000-0001-5208-3432, MGI:csmith] |
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Allelic Composition: Ap3b1tm1Sms/Ap3b1tm1Sms
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6
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| MP:0020039 | increased bone ossification | "increase in the formation of bone or of a bony substance, or the conversion of fibrous tissue or of cartilage into bone or a bony substance" [ORCID: orcid.org/0000-0003-4606-0597] |
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Allelic Composition: Ap3b1tm1Sms/Ap3b1tm1Sms
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6
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| MP:0020040 | decreased bone ossification | "decrease in the formation of bone or of a bony substance, or the conversion of fibrous tissue or of cartilage into bone or a bony substance" [ORCID: orcid.org/0000-0003-4606-0597] |
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Allelic Composition: Cry1tm1Jhjh/Cry1tm1Jhjh,Per2tm1Brd/Per2tm1Brd
Genetic Background: involves: 129P2/OlaHsd * 129S7/SvEvBrd * C57BL/6
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| MP:0020414 | abnormal fibroblast physiology | "any functional anomaly in the cellular physiological processes carried out by a fibroblast cell population" [mgi:anna] |
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Allelic Composition: Arntltm1Bra/Arntltm1Bra
Genetic Background: involves: 129/Sv * C57BL/6
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| MP:0020468 | abnormal circadian behavior period | "any change in the cycle length of a behavior expressed when exposed to constant conditions without temporal cues" [MGI:smb] |
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Allelic Composition: Clockm1Jt/Clock+,Per2tm1Jt/Per2+,Usf1soc/?
Genetic Background: involves: 129S6/SvEvTac * BALB/cJ * C57BL/6J
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| MP:0020469 | prolonged circadian behavior period | "increase in the cycle length of a behavior expressed when exposed to constant conditions without temporal cues" [MGI:smb] |
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Allelic Composition: Myrftm1Barr/Myrftm1Barr,Cnptm1(cre)Kan/Cnp+
Genetic Background: involves: 129P2/OlaHsd * 129S1/Sv * 129S4/SvJaeSor * 129X1/SvJ * C57BL/6
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| MP:0020470 | shortened circadian behavior period | "decrease in the cycle length of a behavior expressed when exposed to constant conditions without temporal cues" [MGI:smb] |
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Allelic Composition: Ap3b1tm1Sms/Ap3b1tm1Sms
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6
Allelic Composition: Per2tm1Ccl/Per2tm1Ccl
Genetic Background: involves: 129 * C57BL/6
Allelic Composition: Per2tm1Drw/Per2tm1Drw,Tg(PER2*S662G)867Ljp/0
Genetic Background: involves: C57BL/6
Allelic Composition: Per2Kort/Per2Kort
Genetic Background: C57BL/6J-Per2Kort
Allelic Composition: Per2Kort/Per2+
Genetic Background: C57BL/6J-Per2Kort
|
| MP:0020472 | arrhythmic circadian behavior persistence | "loss of a behavioral rhythmic pattern upon removal of time cues" [MGI:smb] |
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Allelic Composition: Ap3b1tm1Sms/Ap3b1tm1Sms
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6
Allelic Composition: Per1tm1Brd/Per1tm1Brd,Per2tm1Brd/Per2tm1Brd
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6
Allelic Composition: Cry1tm1Jhjh/Cry1tm1Jhjh,Per2tm1Brd/Per2tm1Brd
Genetic Background: involves: 129P2/OlaHsd * 129S7/SvEvBrd * C57BL/6
Allelic Composition: Per2tm1Ccl/Per2tm1Ccl
Genetic Background: involves: 129 * C57BL/6
Allelic Composition: Per1tm1Drw/Per1tm1Drw,Per2tm1Drw/Per2tm1Drw
Genetic Background: involves: 129S4/SvJae
Allelic Composition: Per2tm1Drw/Per2tm1Drw
Genetic Background: involves: 129/Sv
Allelic Composition: Per2tm1Drw/Per2tm1Drw,Per3tm1Drw/Per3tm1Drw
Genetic Background: involves: 129/Sv * 129S4/SvJae
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| MP:0020477 | abnormal locomotor circadian rhythm | "any anomaly in the rhythm of the locomotor activity of an organism during its 24 hour activity cycle" [GO:0045475] |
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Allelic Composition: Ap3b1tm1Sms/Ap3b1tm1Sms
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6
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| MP:0020478 | abnormal circadian sleep/wake cycle | "any anomaly in the cycle from wakefulness through an orderly succession of sleep states and stages that occurs on an approximately 24 hour rhythm" [GO:0042745] |
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Allelic Composition: Ap3b1tm1Sms/Ap3b1tm1Sms
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6
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| MP:0030438 | increased osteoblast proliferation | "increase in the expansion rate of osteoblasts by cell division; osteoblasts are skeletogenic cells that secrete osteoid, are capable of producing mineralized (hydroxyapatite) matrix, are located adjacent to or within osteoid tissue, and arise from the transformation of a preosteoblast cell" [MGI:anna] |
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Allelic Composition: Arntltm1Bra/Arntltm1Bra
Genetic Background: involves: 129/Sv * C57BL/6
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