ENSMUSG00000056222


Mus musculus

Features
Gene ID: ENSMUSG00000056222
  
Biological name :Spock1
  
Synonyms : sparc/osteonectin, cwcv and kazal-like domains proteoglycan 1 / Spock1
  
Possible biological names infered from orthology : Q08629
  
Species: Mus musculus
  
Chr. number: 13
Strand: -1
Band: B1
Gene start: 57421195
Gene end: 57908332
  
Corresponding Affymetrix probe sets: 10409616 (MoGene1.0st)   1419672_at (Mouse Genome 430 2.0 Array)   1419673_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000141130
Ensembl peptide - ENSMUSP00000140755
Ensembl peptide - ENSMUSP00000153001
Ensembl peptide - ENSMUSP00000128840
Ensembl peptide - ENSMUSP00000139863
Ensembl peptide - ENSMUSP00000140409
NCBI entrez gene - 20745     See in Manteia.
MGI - MGI:105371
RefSeq - NM_001166464
RefSeq - NM_001166463
RefSeq - NM_001166465
RefSeq - NM_001166466
RefSeq - NM_009262
RefSeq Peptide - NP_001159938
RefSeq Peptide - NP_001159935
RefSeq Peptide - NP_033288
RefSeq Peptide - NP_001159936
RefSeq Peptide - NP_001159937
swissprot - Q6DIC9
swissprot - Q8BM07
swissprot - A0A286YCI6
swissprot - A0A087WPP6
swissprot - Q8BKQ3
Ensembl - ENSMUSG00000056222
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 spock1ENSDARG00000074644Danio rerio
 SPOCK1ENSGALG00000006258Gallus gallus
 Q08629ENSG00000152377Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q8BKV0 / Spock3 / Testican-3 / Q9BQ16* / SPARC/osteonectin, cwcv and kazal like domains proteoglycan 3*ENSMUSG0000005416252
Q9ER58 / Spock2 / Testican-2 / Q92563* / SPARC/osteonectin, cwcv and kazal like domains proteoglycan 2*ENSMUSG0000005829743


Protein motifs (from Interpro)
Interpro ID Name
 IPR000716  Thyroglobulin type-1
 IPR002350  Kazal domain
 IPR011992  EF-hand domain pair
 IPR019577  SPARC/Testican, calcium-binding domain
 IPR036058  Kazal domain superfamily
 IPR036857  Thyroglobulin type-1 superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007165 signal transduction IEA
 biological_processGO:0010812 negative regulation of cell-substrate adhesion IEA
 biological_processGO:0010951 negative regulation of endopeptidase activity IEA
 biological_processGO:0010977 negative regulation of neuron projection development IEA
 cellular_componentGO:0005615 extracellular space IEA
 molecular_functionGO:0004869 cysteine-type endopeptidase inhibitor activity IEA
 molecular_functionGO:0005509 calcium ion binding IEA
 molecular_functionGO:0005515 protein binding IEA
 molecular_functionGO:0008191 metalloendopeptidase inhibitor activity IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0002169 no phenotype detected "normal, viable and fertile appearance and behavior; indistinguishable from controls" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Pla2g15tm1.1Jash/Pla2g15tm1.1Jash
Genetic Background: involves: 129S1/Sv * C57BL/6

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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