ENSMUSG00000057554


Mus musculus

Features
Gene ID: ENSMUSG00000057554
  
Biological name :Lgals8
  
Synonyms : Galectin-8 / Lgals8 / Q9JL15
  
Possible biological names infered from orthology : O00214
  
Species: Mus musculus
  
Chr. number: 13
Strand: -1
Band: A1
Gene start: 12439415
Gene end: 12464944
  
Corresponding Affymetrix probe sets: 10407766 (MoGene1.0st)   1422661_at (Mouse Genome 430 2.0 Array)   1422662_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000120210
Ensembl peptide - ENSMUSP00000115094
Ensembl peptide - ENSMUSP00000118925
Ensembl peptide - ENSMUSP00000097408
Ensembl peptide - ENSMUSP00000097409
Ensembl peptide - ENSMUSP00000114200
NCBI entrez gene - 56048     See in Manteia.
MGI - MGI:1928481
RefSeq - XM_017315549
RefSeq - NM_001199043
RefSeq - NM_001291055
RefSeq - NM_001291057
RefSeq - NM_001291060
RefSeq - NM_018886
RefSeq - XM_006516715
RefSeq - XM_011244320
RefSeq - XM_011244321
RefSeq - XM_011244322
RefSeq - XM_011244323
RefSeq - XM_011244324
RefSeq - XM_011244325
RefSeq - XM_017315547
RefSeq - XM_017315548
RefSeq - XM_006516714
RefSeq Peptide - NP_001185972
RefSeq Peptide - NP_001277984
RefSeq Peptide - NP_001277986
RefSeq Peptide - NP_001277989
RefSeq Peptide - NP_061374
swissprot - Q542M5
swissprot - Q8C6H0
swissprot - Q9JL15
swissprot - A8DIL0
Ensembl - ENSMUSG00000057554
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 lgals8aENSDARG00000037066Danio rerio
 lgals8bENSDARG00000037613Danio rerio
 LGALS8ENSGALG00000014371Gallus gallus
 LGALS8ENSG00000116977Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Lgals9 / O08573 / Galectin-9 / Q6DKI2* / O00182* / Q3B8N2* / LGALS9B* / LGALS9C* / galectin 9B* / galectin 9C*ENSMUSG0000000112336
Lgals4 / Q8K419 / Galectin-4 / P56470*ENSMUSG0000005396435
Q91VD1 / Lgals12 / Mus musculus lectin, galactose binding, soluble 12 (Lgals12), transcript variant 2, mRNA. / Q96DT0* / galectin 12*ENSMUSG0000002497226
Lgals3 / galectin 3 / P17931*ENSMUSG0000005033520
Lgalsl / Q8VED9 / Galectin-related protein / Q3ZCW2* / galectin like*ENSMUSG0000004236313
Grifin / Q9D1U0 / A4D1Z8* / galectin-related inter-fiber protein*ENSMUSG0000003658613
Lgals7 / P47929* / LGALS7B* / galectin 7* / galectin 7B*ENSMUSG0000005352213
Gm5065 / Q7TPX9 / Galectin-related protein B / LGALSL* / Q3ZCW2* / galectin like*ENSMUSG0000004839812


Protein motifs (from Interpro)
Interpro ID Name
 IPR001079  Galectin, carbohydrate recognition domain
 IPR013320  Concanavalin A-like lectin/glucanase domain superfamily
 IPR030638  Galectin-8


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0002317 plasma cell differentiation IDA
 biological_processGO:0006914 autophagy IEA
 biological_processGO:0031295 T cell costimulation IDA
 biological_processGO:0098586 cellular response to virus ISS
 biological_processGO:0098792 xenophagy ISO
 biological_processGO:1904977 lymphatic endothelial cell migration ISO
 cellular_componentGO:0005737 cytoplasm ISS
 cellular_componentGO:0005829 cytosol IEA
 cellular_componentGO:0031410 cytoplasmic vesicle IEA
 molecular_functionGO:0005178 integrin binding ISO
 molecular_functionGO:0030246 carbohydrate binding ISO


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0001399 hyperactivity "general restlessness or excessive movement; more frequent movement from one place to another" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:60409, J:57125]
Show

Allelic Composition: Casp9tm1Flv/Casp9tm1Flv
Genetic Background: B6.129S1-Casp9tm1Flv

 MP:0002410 decreased susceptibility to viral infection "reduced likelihood that an organism will develop ill effects from a viral infection or from components of or toxins produced by a virus " [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
Show

Allelic Composition: Sun1tm1.1Ktj/Sun1+,Sun2tm1.1Cyh/Sun2tm1.1Cyh
Genetic Background: involves: 129/Sv * C57BL/6 * C57BL/6N

 MP:0008778 lymphangiogenesis "any anomaly in the formation of lymphatic vessels from pre-existing lymphatic vessels" [MESH:G07.574.500.325.377.500]
Show

Allelic Composition: Sun1tm1.1Ktj/Sun1+,Sun2tm1.1Cyh/Sun2tm1.1Cyh
Genetic Background: involves: 129/Sv * C57BL/6 * C57BL/6N

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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