ENSMUSG00000057967


Mus musculus

Features
Gene ID: ENSMUSG00000057967
  
Biological name :Fgf18
  
Synonyms : Fgf18 / Fibroblast growth factor 18 / O89101
  
Possible biological names infered from orthology : O76093
  
Species: Mus musculus
  
Chr. number: 11
Strand: -1
Band: A4
Gene start: 33117430
Gene end: 33147400
  
Corresponding Affymetrix probe sets: 10385036 (MoGene1.0st)   1449545_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000020507
Ensembl peptide - ENSMUSP00000104987
NCBI entrez gene - 14172     See in Manteia.
MGI - MGI:1277980
RefSeq - NM_008005
RefSeq Peptide - NP_032031
swissprot - O89101
swissprot - Q5SQB3
Ensembl - ENSMUSG00000057967
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 fgf18aENSDARG00000088048Danio rerio
 fgf18bENSDARG00000043962Danio rerio
 FGF18ENSGALG00000002203Gallus gallus
 FGF18ENSG00000156427Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Fgf8 / P37237 / Fibroblast growth factor 8 / P55075*ENSMUSG0000002521945
Fgf17 / P63075 / Fibroblast growth factor 17 / O60258*ENSMUSG0000002210145


Protein motifs (from Interpro)
Interpro ID Name
 IPR002209  Fibroblast growth factor family
 IPR008996  Cytokine IL1/FGF
 IPR028289  Fibroblast growth factor 18


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001503 ossification IMP
 biological_processGO:0001525 angiogenesis IMP
 biological_processGO:0001957 intramembranous ossification IMP
 biological_processGO:0001958 endochondral ossification IMP
 biological_processGO:0002063 chondrocyte development IMP
 biological_processGO:0007165 signal transduction TAS
 biological_processGO:0008284 positive regulation of cell proliferation IMP
 biological_processGO:0008543 fibroblast growth factor receptor signaling pathway IGI
 biological_processGO:0010469 regulation of signaling receptor activity IEA
 biological_processGO:0030324 lung development IMP
 biological_processGO:0030949 positive regulation of vascular endothelial growth factor receptor signaling pathway IMP
 biological_processGO:0032332 positive regulation of chondrocyte differentiation IGI
 biological_processGO:0043406 positive regulation of MAP kinase activity IEA
 biological_processGO:0043536 positive regulation of blood vessel endothelial cell migration IEA
 biological_processGO:0045766 positive regulation of angiogenesis IEA
 biological_processGO:0070374 positive regulation of ERK1 and ERK2 cascade IDA
 biological_processGO:2000546 positive regulation of endothelial cell chemotaxis to fibroblast growth factor IEA
 cellular_componentGO:0005576 extracellular region IEA
 cellular_componentGO:0005730 nucleolus IEA
 molecular_functionGO:0005104 fibroblast growth factor receptor binding TAS
 molecular_functionGO:0005105 type 1 fibroblast growth factor receptor binding IEA
 molecular_functionGO:0005111 type 2 fibroblast growth factor receptor binding IEA
 molecular_functionGO:0008083 growth factor activity IEA


Pathways (from Reactome)
Pathway description
PI3K Cascade
PIP3 activates AKT signaling
FGFR4 ligand binding and activation
FGFR3b ligand binding and activation
FGFR3c ligand binding and activation
FGFR2c ligand binding and activation
Phospholipase C-mediated cascade; FGFR2
Phospholipase C-mediated cascade; FGFR3
Phospholipase C-mediated cascade; FGFR4
FRS-mediated FGFR1 signaling
PI-3K cascade:FGFR2
SHC-mediated cascade:FGFR2
FRS-mediated FGFR2 signaling
SHC-mediated cascade:FGFR3
FRS-mediated FGFR3 signaling
PI-3K cascade:FGFR3
FRS-mediated FGFR4 signaling
SHC-mediated cascade:FGFR4
PI-3K cascade:FGFR4
Negative regulation of FGFR2 signaling
Negative regulation of FGFR3 signaling
Negative regulation of FGFR4 signaling
FGFRL1 modulation of FGFR1 signaling
RAF/MAP kinase cascade
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0000060 delayed bone ossification "late onset of the formation of bone" [J:40203]
Show

Allelic Composition: Dclre1ctm1.1Fwa/Dclre1ctm1.1Fwa
Genetic Background: involves: 129S6/SvEvTac * C57BL/6

Allelic Composition: Fgf18tm1Dor/Fgf18tm1Dor
Genetic Background: involves: 129X1/SvJ * C57BL/6J

 MP:0000074 abnormal neurocranium morphology "malformed bones of the skull enclosing the brain" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:55583]
Show

Allelic Composition: Fgf18tm1Dor/Fgf18tm1Dor
Genetic Background: involves: 129X1/SvJ * C57BL/6J

 MP:0000150 abnormal rib morphology "malformed bones forming the bony wall of the chest" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, J:50311]
Show

Allelic Composition: Dclre1ctm1.1Fwa/Dclre1ctm1.1Fwa
Genetic Background: involves: 129S6/SvEvTac * C57BL/6

Allelic Composition: Fgf18tm1Dor/Fgf18tm1Dor
Genetic Background: involves: 129X1/SvJ * C57BL/6J

Allelic Composition: Fgf18tm1Sjt/Fgf18tm1Sjt,Glg1Gt(KST005)Byg/Glg1Gt(KST005)Byg
Genetic Background: B6.129-Glg1Gt(KST005)Byg Fgf18tm1Sjt

Allelic Composition: Fgf18tm1Sjt/Fgf18tm1Sjt
Genetic Background: B6.129S1-Fgf18tm1Sjt

Allelic Composition: Fgf18tm1Sjt/Fgf18tm1Sjt,Glg1Gt(KST005)Byg/Glg1+
Genetic Background: B6.129-Glg1Gt(KST005)Byg Fgf18tm1Sjt

 MP:0000160 kyphosis "forward curvature of the spine, characterized by extensive flexion. " [J:62023, J:66943, Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, cml:Cathleen M. Lutz , Mouse Genome Informatics Curator]
Show

Allelic Composition: Dclre1ctm1.1Fwa/Dclre1ctm1.1Fwa
Genetic Background: involves: 129S6/SvEvTac * C57BL/6

 MP:0000427 abnormal hair cycle "aberrant growth or asynchronous timing of the hair growth " [J:65302]
Show

Allelic Composition: PhexMhdabap024/PhexMhdabap024
Genetic Background: C3HeB/FeJ-PhexMhdabap024

 MP:0000457 maxilla hypoplasia "arrested growth or atrophy of the upper bony framework of the mouth where the superior teeth are held" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, tc:Teresa Chu , Mouse Genome Informatics Curator, J:54637]
Show

Allelic Composition: Fgf18tm1Dor/Fgf18tm1Dor
Genetic Background: involves: 129X1/SvJ * C57BL/6J

 MP:0001176 abnormal lung development "malformation or arrest of differentiation of the organs of respiration" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:54931]
Show

Allelic Composition: Dclre1ctm1.1Fwa/Dclre1ctm1.1Fwa
Genetic Background: involves: 129S6/SvEvTac * C57BL/6

 MP:0001262 decreased body weight "lower than normal average weight " [J:61295]
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Allelic Composition: Fgf18tm1Sjt/Fgf18+,Glg1Gt(KST005)Byg/Glg1+
Genetic Background: B6.129-Glg1Gt(KST005)Byg Fgf18tm1Sjt

 MP:0001510 abnormal coat appearance "coat that looks different from the usual state " [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
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Allelic Composition: PhexMhdabap024/PhexMhdabap024
Genetic Background: C3HeB/FeJ-PhexMhdabap024

 MP:0001575 cyanosis "a dark bluish or purple skin discoloration resulting from deficient oxygenation of the blood" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:60159]
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Allelic Composition: Fgf18tm1Dor/Fgf18tm1Dor
Genetic Background: involves: 129X1/SvJ * C57BL/6J

 MP:0002109 abnormal limb morphology "abnormal development of limbs resulting in morphological abnormality" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Gata1tm1Phi/Y,Tg(Dhh-cre)1Mejr/0
Genetic Background: involves: 129P2/OlaHsd * C57BL/6 * FVB

 MP:0002111 abnormal tail morphology "abnormal development of the tail resulting in structural abnormality" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Fgf18tm1Sjt/Fgf18+,Glg1Gt(KST005)Byg/Glg1+
Genetic Background: B6.129-Glg1Gt(KST005)Byg Fgf18tm1Sjt

Allelic Composition: Fgf18tm1Sjt/Fgf18tm1Sjt,Glg1Gt(KST005)Byg/Glg1Gt(KST005)Byg
Genetic Background: B6.129-Glg1Gt(KST005)Byg Fgf18tm1Sjt

Allelic Composition: Fgf18tm1Sjt/Fgf18+,Glg1Gt(KST005)Byg/Glg1Gt(KST005)Byg
Genetic Background: B6.129-Glg1Gt(KST005)Byg Fgf18tm1Sjt

 MP:0002113 abnormal skeleton development "anomalous differentiation or remodeling of bone tissue resulting in morphological abnormality" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Gata1tm1Phi/Y,Tg(Dhh-cre)1Mejr/0
Genetic Background: involves: 129P2/OlaHsd * C57BL/6 * FVB

 MP:0002114 abnormal axial skeleton morphology "abnormal development of vertebral, spinal or sternal bones resulting in morphological abnormality" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Gata1tm1Phi/Y,Tg(Dhh-cre)1Mejr/0
Genetic Background: involves: 129P2/OlaHsd * C57BL/6 * FVB

 MP:0002115 abnormal skeleton extremities morphology "abnormal development of limb, foot or tail bones resulting in morphological abnormality" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Gata1tm1Phi/Y,Tg(Dhh-cre)1Mejr/0
Genetic Background: involves: 129P2/OlaHsd * C57BL/6 * FVB

 MP:0002116 abnormal craniofacial bone morphology "abnormal development of cranial or facial bones resulting in morphological abnormality" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Gata1tm1Phi/Y,Tg(Dhh-cre)1Mejr/0
Genetic Background: involves: 129P2/OlaHsd * C57BL/6 * FVB

 MP:0002187 abnormal fibula morphology "malformation of the lateral and smaller bone of the lower limb" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Dclre1ctm1.1Fwa/Dclre1ctm1.1Fwa
Genetic Background: involves: 129S6/SvEvTac * C57BL/6

Allelic Composition: Fgf18tm1Dor/Fgf18tm1Dor
Genetic Background: involves: 129X1/SvJ * C57BL/6J

 MP:0002314 abnormal respiratory mechanics "anomaly in the action of the lungs, diaphragm, ribs and chest wall during respiration" [MeSH:National Library of Medicine - Medical Subject Headings , 2003, cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
Show

Allelic Composition: Fgf18tm1Dor/Fgf18tm1Dor
Genetic Background: involves: 129X1/SvJ * C57BL/6J

 MP:0002764 short tibia " reduced length of the medial and larger bone of the lower leg" [J:12736, pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator]
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Allelic Composition: Dclre1ctm1.1Fwa/Dclre1ctm1.1Fwa
Genetic Background: involves: 129S6/SvEvTac * C57BL/6

 MP:0002835 abnormal cranial suture morphology "defects of the fibrous joint in the bones of the head" [MeSH:National Library of Medicine - Medical Subject Headings , 2003, pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator, J:62161]
Show

Allelic Composition: Fgf18tm1Dor/Fgf18tm1Dor
Genetic Background: involves: 129X1/SvJ * C57BL/6J

 MP:0003072 abnormal metatarsal bone morphology "anomaly in the five bones of the hindpaws that articulate proximally with the cuneiform and cuboid bones of the tarsus and distally with the phlanges" [Stedman s Medical Dictionary, 27th edition:ISBN 0-683-40008-8, Anatomy of the Rat:Greene, EC, Hafner Publishing Co, 1935]
Show

Allelic Composition: Fgf18tm1Dor/Fgf18tm1Dor
Genetic Background: involves: 129X1/SvJ * C57BL/6J

 MP:0003408 increased width of hypertrophic chondrocyte zone "increased width of cartilage cell matrix layer " [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]
Show

Allelic Composition: Fgf18tm1Dor/Fgf18tm1Dor
Genetic Background: involves: 129X1/SvJ * C57BL/6J

 MP:0003419 delayed endochondral bone ossification "late onset of bone formation in bones that form from cartilage" [smb:Susan M Bello, Mouse Genome Informatics Curator, J:94631]
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Allelic Composition: Fgf18tm1Dor/Fgf18tm1Dor
Genetic Background: involves: 129X1/SvJ * C57BL/6J

 MP:0003420 delayed intramembranous bone ossification "late onset of bone formation in bones that form without a cartilagenous intermediate including the cranium and clavicle" [smb:Susan M Bello, Mouse Genome Informatics Curator, J:94631]
Show

Allelic Composition: Fgf18tm1Dor/Fgf18tm1Dor
Genetic Background: involves: 129X1/SvJ * C57BL/6J

 MP:0003641 small lung "reduced size of the lung relative to normal" [smb:Susan M Bello, Mouse Genome Informatics Curator, J:95332]
Show

Allelic Composition: Dclre1ctm1.1Fwa/Dclre1ctm1.1Fwa
Genetic Background: involves: 129S6/SvEvTac * C57BL/6

 MP:0003662 abnormal proliferative zone "germinal layer of the epiphyseal plate where cells are actively dividing as well as producing extracellular matrix" [smb:Susan M Bello, Mouse Genome Informatics Curator, J:96254]
Show

Allelic Composition: Fgf18tm1Dor/Fgf18tm1Dor
Genetic Background: involves: 129X1/SvJ * C57BL/6J

 MP:0004007 abnormal lung vasculature "malformation or disorganization of the blood vessels of the lung" [smb:Susan M Bello, Mouse Genome Informatics Curator]
Show

Allelic Composition: Dclre1ctm1.1Fwa/Dclre1ctm1.1Fwa
Genetic Background: involves: 129S6/SvEvTac * C57BL/6

 MP:0004174 abnormal spine curvature "deviation from the typical S-shape of the spine" [smb:Susan M Bello, Mouse Genome Informatics Curator]
Show

Allelic Composition: Fgf18tm1Sjt/Fgf18tm1Sjt,Glg1Gt(KST005)Byg/Glg1Gt(KST005)Byg
Genetic Background: B6.129-Glg1Gt(KST005)Byg Fgf18tm1Sjt

Allelic Composition: Fgf18tm1Sjt/Fgf18tm1Sjt,Glg1Gt(KST005)Byg/Glg1+
Genetic Background: B6.129-Glg1Gt(KST005)Byg Fgf18tm1Sjt

 MP:0004355 short radius "reduced length of the short bone of the lateral forearm" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"]
Show

Allelic Composition: Dclre1ctm1.1Fwa/Dclre1ctm1.1Fwa
Genetic Background: involves: 129S6/SvEvTac * C57BL/6

 MP:0004358 bowed tibia "increased curvature of the medial and larger of the two bones of the lower leg" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"]
Show

Allelic Composition: Fgf18tm1Dor/Fgf18tm1Dor
Genetic Background: involves: 129X1/SvJ * C57BL/6J

 MP:0004359 short ulna "reduced length of the medial and larger of the two bones of the forearm" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"]
Show

Allelic Composition: Dclre1ctm1.1Fwa/Dclre1ctm1.1Fwa
Genetic Background: involves: 129S6/SvEvTac * C57BL/6

 MP:0004374 bowed radius "increased curvature of the short bone of the lateral forearm" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"]
Show

Allelic Composition: Fgf18tm1Dor/Fgf18tm1Dor
Genetic Background: involves: 129X1/SvJ * C57BL/6J

 MP:0004734 small thoracic cavity "reduced size of the cavity in the vertebrate body enclosed by the ribcage between the diaphragm and the neck, and contains the lungs, heart, thoracic aorta, pulmonary artery and its branches, thymus gland, and the respiratory airway" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Dclre1ctm1.1Fwa/Dclre1ctm1.1Fwa
Genetic Background: involves: 129S6/SvEvTac * C57BL/6

Allelic Composition: Fgf18tm1Dor/Fgf18tm1Dor
Genetic Background: involves: 129X1/SvJ * C57BL/6J

 MP:0005508 abnormal skeleton morphology "malformation of the bony framework of the body in vertebrates" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
Show

Allelic Composition: Fgf18tm1Sjt/Fgf18+,Glg1Gt(KST005)Byg/Glg1Gt(KST005)Byg
Genetic Background: B6.129-Glg1Gt(KST005)Byg Fgf18tm1Sjt

 MP:0006398 increased long bone epiphyseal plate size "greater than the normal size of the cartilaginous center of ossification on the long bones permitting growth of the bone in both directions during development" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Fgf18tm1Dor/Fgf18tm1Dor
Genetic Background: involves: 129X1/SvJ * C57BL/6J

 MP:0008395 abnormal osteoblast differentiation "atypical production of or inability to produce bone-forming cells, which normally form an osseous matrix (osteoid) in which they become enclosed as an osteocytes" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Fgf18tm1Dor/Fgf18tm1Dor
Genetic Background: involves: 129X1/SvJ * C57BL/6J

 MP:0008858 abnormal hair cycle anagen phase "anomaly in the growth phase of the hair cycle" [MGI:llw2 "Linda Washburn, Mouse Genome Informatics Curator"]
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Allelic Composition: PhexMhdabap024/PhexMhdabap024
Genetic Background: C3HeB/FeJ-PhexMhdabap024

 MP:0008860 abnormal hair cycle telogen phase "anomaly in the resting or quiescent phase of the hair growth cycle which follows cessation of proliferation (catagen) and preceeds hair loss" [MGI:llw2 "Linda Washburn, Mouse Genome Informatics Curator"]
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Allelic Composition: PhexMhdabap024/PhexMhdabap024
Genetic Background: C3HeB/FeJ-PhexMhdabap024

 MP:0009703 decreased birth body size "reduction in average body size at birth compared to controls" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"]
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Allelic Composition: Fgf18tm1Dor/Fgf18tm1Dor
Genetic Background: involves: 129X1/SvJ * C57BL/6J

 MP:0009886 failure of palatal shelf elevation "the palatal shelves fail to move from a vertical position in the orofacial cavity to a horizontal apposition above the developing tongue" [PMID:16680722]
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Allelic Composition: Fgf18tm1Dor/Fgf18tm1Dor
Genetic Background: involves: 129X1/SvJ * C57BL/6J

 MP:0009890 cleft secondary palate "congenital fissure of the tissues normally uniting to form the secondary palate" [PMID:16680722]
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Allelic Composition: Fgf18tm1Dor/Fgf18tm1Dor
Genetic Background: involves: 129X1/SvJ * C57BL/6J

 MP:0010743 delayed suture closure "late onset of the fusion of the bones of the skull" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Dclre1ctm1.1Fwa/Dclre1ctm1.1Fwa
Genetic Background: involves: 129S6/SvEvTac * C57BL/6

 MP:0010825 abnormal lung saccule morphology "any structural anomaly of the transient dilations of the developing alveolar (or transient) ducts, which transform into a transitory alveolar duct as soon as it develops further branches; the last transitory saccule formed on each pathway is a terminal saccule that develops into an alveolar sac after birth" [GO:0060430, ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition", MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Dclre1ctm1.1Fwa/Dclre1ctm1.1Fwa
Genetic Background: involves: 129S6/SvEvTac * C57BL/6

 MP:0010976 small lung lobe "reduced size of any of the anatomically and functionally distinct subunits (lobes) comprising the left or right lung, where each lobe receives air from its own secondary bronchus and is separated from it neighbors by one or more fissures (walls of connective tissue)" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"]
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Allelic Composition: Dclre1ctm1.1Fwa/Dclre1ctm1.1Fwa
Genetic Background: involves: 129S6/SvEvTac * C57BL/6

 MP:0011086 partial postnatal lethality "the appearance of lower than Mendelian ratios of organisms of a given genotype due to death of some, but not all of the organisms anytime between the neonatal period and weaning age (Mus: P1 to approximately 3 weeks of age)" [MGI:csmith]
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Allelic Composition: Fgf18tm1Sjt/Fgf18+,Glg1Gt(KST005)Byg/Glg1Gt(KST005)Byg
Genetic Background: B6.129-Glg1Gt(KST005)Byg Fgf18tm1Sjt

 MP:0011087 complete neonatal lethality "death of all organisms of a given genotype in a population within the neonatal period after birth (Mus: P0)" [MGI:csmith]
Show

Allelic Composition: Fgf18tm1Dor/Fgf18tm1Dor
Genetic Background: involves: 129X1/SvJ * C57BL/6J

Allelic Composition: Fgf18tm1Sjt/Fgf18tm1Sjt,Glg1Gt(KST005)Byg/Glg1Gt(KST005)Byg
Genetic Background: B6.129-Glg1Gt(KST005)Byg Fgf18tm1Sjt

Allelic Composition: Fgf18tm1Sjt/Fgf18tm1Sjt
Genetic Background: B6.129S1-Fgf18tm1Sjt

Allelic Composition: Fgf18tm1Sjt/Fgf18tm1Sjt,Glg1Gt(KST005)Byg/Glg1+
Genetic Background: B6.129-Glg1Gt(KST005)Byg Fgf18tm1Sjt

 MP:0011089 complete perinatal lethality "death of all organisms of a given genotype in a population within the perinatal period (Mus: E18.5 through postnatal day 1)" [MGI:csmith]
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Allelic Composition: Dclre1ctm1.1Fwa/Dclre1ctm1.1Fwa
Genetic Background: involves: 129S6/SvEvTac * C57BL/6

 MP:0011143 thick lung-associated mesenchyme "increased thickness of the mesenchymal cell layer due to delay or failure of the mesenchymal compartment to thin down during the late stages of embryonic lung development" [MGI:anna]
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Allelic Composition: Dclre1ctm1.1Fwa/Dclre1ctm1.1Fwa
Genetic Background: involves: 129S6/SvEvTac * C57BL/6

 MP:0030315 small neurocranium "decreased size of the bones of the skull enclosing the brain" [MGI:anna]
Show

Allelic Composition: Fgf18tm1Dor/Fgf18tm1Dor
Genetic Background: involves: 129X1/SvJ * C57BL/6J

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

1 s.

 
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