ENSMUSG00000058806


Mus musculus

Features
Gene ID: ENSMUSG00000058806
  
Biological name :Col13a1
  
Synonyms : Col13a1 / Collagen alpha-1(XIII) chain / Q9R1N9
  
Possible biological names infered from orthology : collagen type XIII alpha 1 chain / Q5TAT6
  
Species: Mus musculus
  
Chr. number: 10
Strand: -1
Band: B4
Gene start: 61838236
Gene end: 61979108
  
Corresponding Affymetrix probe sets: 10369485 (MoGene1.0st)   1422866_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000117248
Ensembl peptide - ENSMUSP00000101092
Ensembl peptide - ENSMUSP00000101093
Ensembl peptide - ENSMUSP00000101094
NCBI entrez gene - 12817     See in Manteia.
MGI - MGI:1277201
RefSeq - XM_011243344
RefSeq - XM_011243336
RefSeq - XM_011243337
RefSeq - XM_011243339
RefSeq - XM_011243341
RefSeq - XM_011243342
RefSeq - XM_011243343
RefSeq - NM_001304757
RefSeq - NM_007731
RefSeq - XM_006513170
RefSeq - XM_006513171
RefSeq - XM_011243322
RefSeq - XM_011243323
RefSeq - XM_011243324
RefSeq - XM_011243325
RefSeq - XM_011243326
RefSeq - XM_011243327
RefSeq - XM_011243328
RefSeq - XM_011243329
RefSeq - XM_011243330
RefSeq - XM_011243331
RefSeq - XM_011243332
RefSeq - XM_011243333
RefSeq - XM_011243335
RefSeq Peptide - NP_001291686
RefSeq Peptide - NP_031757
swissprot - F6Y6J7
swissprot - D3Z7B9
swissprot - Q9R1N9
swissprot - D3Z7B8
Ensembl - ENSMUSG00000058806
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 COL13A1ENSGALG00000004286Gallus gallus
 Q5TAT6ENSG00000197467Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q99MQ5 / Col25a1 / Collagen alpha-1(XXV) chain Collagen-like Alzheimer amyloid plaque component / Q9BXS0* / collagen type XXV alpha 1 chain*ENSMUSG0000005889737
Col9a3 / collagen, type IX, alpha 3 / Q14050* / collagen type IX alpha 3 chain*ENSMUSG0000002757034
Q8K4G2 / Col23a1 / Collagen alpha-1(XXIII) chain / Q86Y22* / collagen type XXIII alpha 1 chain*ENSMUSG0000006356434
Col9a1 / collagen type IX alpha 1 chain / P20849*ENSMUSG0000002614733
Col9a2 / collagen type IX alpha 2 chain / Q14055*ENSMUSG0000002862632


Protein motifs (from Interpro)
Interpro ID Name
 IPR008160  Collagen triple helix repeat
 IPR016133  Insect cysteine-rich antifreeze protein


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001503 ossification IEA
 biological_processGO:0001763 morphogenesis of a branching structure IEP
 biological_processGO:0001958 endochondral ossification IEP
 biological_processGO:0007155 cell adhesion IEA
 biological_processGO:0007160 cell-matrix adhesion IEA
 biological_processGO:0007275 multicellular organism development IEA
 biological_processGO:0030154 cell differentiation IEA
 biological_processGO:0098609 cell-cell adhesion IEA
 cellular_componentGO:0005581 collagen trimer IEA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0005911 cell-cell junction IDA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0030054 cell junction IEA
 cellular_componentGO:0045202 synapse IEA
 cellular_componentGO:0045211 postsynaptic membrane IEA
 molecular_functionGO:0008201 heparin binding IEA


Pathways (from Reactome)
Pathway description
Collagen degradation
Collagen biosynthesis and modifying enzymes
Integrin cell surface interactions
Collagen chain trimerization


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0000745 tremors "repetitive, cyclical movements of the body or a body part; usually involuntary, but can also manifest in response to an attempt at movement" [MeSH:National Library of Medicine - Medical Subject Headings , 2003, Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]
Show

Allelic Composition: Col13a1tm1Pih/Col13a1tm1Pih
Genetic Background: involves: 129S1/Sv * 129X1/SvJ

 MP:0000749 muscle degeneration "pathological deterioration of muscle tissue, often accompanied by loss of function" [csmith:Cynthia L. Smith, Mouse Genome Informatics Curator]
Show

Allelic Composition: Wnt3tm1Amc/Wnt3tm2Amc,Tg(Rarb-cre)1Mrc/0
Genetic Background: involves: 129S1/Sv * 129S7/SvEvBrd * 129X1/SvJ

 MP:0000751 myopathy "any abnormal condition or disease of the skeletal muscle" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:42574]
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Allelic Composition: Wnt3tm1Amc/Wnt3tm2Amc,Tg(Rarb-cre)1Mrc/0
Genetic Background: involves: 129S1/Sv * 129S7/SvEvBrd * 129X1/SvJ

 MP:0000759 abnormal skeletal muscle morphology "anomalous structure of any of the striated muscle fibers connected at either or both extremeties with the bony framework of the body" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
Show

Allelic Composition: Wnt3tm1Amc/Wnt3tm2Amc,Tg(Rarb-cre)1Mrc/0
Genetic Background: involves: 129S1/Sv * 129S7/SvEvBrd * 129X1/SvJ

 MP:0001053 abnormal neuromuscular synapse "malformed or absent membrane to membrane contact of a motor axon and a muscle myofiber resulting in aberrant transmission of nerve impulses" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, MGI:CLS, J:60159, J:47439]
Show

Allelic Composition: Col13a1tm1Pih/Col13a1tm1Pih
Genetic Background: involves: 129S1/Sv * 129X1/SvJ

 MP:0001732 postnatal growth retardation "slow or limited development after birth " [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
Show

Allelic Composition: Col13a1tm1Pih/Col13a1tm1Pih
Genetic Background: involves: 129S1/Sv * 129X1/SvJ

 MP:0002914 abnormal endplate potential activity "defect in the excitatory response of peripheral synapses to stimulation; these amplitudes are larger than central synapse potentials" [Principles of Neural Science , 3rd edition:ISBN 0-8385-8034-3]
Show

Allelic Composition: Etv1tm1.1(cre/ERT2)Zjh/Etv1tm1.1(cre/ERT2)Zjh
Genetic Background: involves: 129 * C57BL/6 * SJL

Allelic Composition: Col13a1tm1Pih/Col13a1tm1Pih
Genetic Background: involves: 129S1/Sv * 129X1/SvJ

Allelic Composition: Col13a1tm3.1Pih/Col13a1tm3.1Pih
Genetic Background: involves: C57BL/6

 MP:0003084 abnormal skeletal muscle fiber morphology "anomalous structure of the skeletal muscle fibers, the large multinucleated cells that make up the skeletal muscles" [smb:Susan M. Bello, Mouse Genome Informatics Curator, Stedman s Medical Dictionary, 27th edition:ISBN 0-683-40008-8]
Show

Allelic Composition: Wnt3tm1Amc/Wnt3tm2Amc,Tg(Rarb-cre)1Mrc/0
Genetic Background: involves: 129S1/Sv * 129S7/SvEvBrd * 129X1/SvJ

 MP:0003566 abnormal cell adhesion "altered ability of a cell to adhere to another cell or to a non-cellular component of the environment" [monikat:Monika Tomczuk, Mouse Genome Informatics Curator]
Show

Allelic Composition: Wnt3tm1Amc/Wnt3tm2Amc,Tg(Rarb-cre)1Mrc/0
Genetic Background: involves: 129S1/Sv * 129S7/SvEvBrd * 129X1/SvJ

 MP:0004091 abnormal Z lines "any structural abnormality in the cross-striation bisecting the I band of striated muscle myofibrils and serving as the anchoring point of actin filaments at either end of the sarcomere" [anna:Anna Anagnostopoulos, Mouse Genome Informatics Curator]
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Allelic Composition: Wnt3tm1Amc/Wnt3tm2Amc,Tg(Rarb-cre)1Mrc/0
Genetic Background: involves: 129S1/Sv * 129S7/SvEvBrd * 129X1/SvJ

 MP:0004121 abnormal sarcolemma morphology "structural anomaly in the plasma membrane of a muscle fiber that is cabable of conducting electrical impuses" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]
Show

Allelic Composition: Wnt3tm1Amc/Wnt3tm2Amc,Tg(Rarb-cre)1Mrc/0
Genetic Background: involves: 129S1/Sv * 129S7/SvEvBrd * 129X1/SvJ

 MP:0004272 abnormal basement membrane morphology "anomaly in the structure, organization and/or placement of the extracellular supportive tissue adjacent to the basal surface of the epithelia, including the epithelium of muscle cells, fat cells and Schwann cells; it is comprised of type IV collagen, laminin, and sulfated proteoglycans and other components and consists of two layers, the basal lamina and the lamina reticularis" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition", MESH:A10.272.220]
Show

Allelic Composition: Wnt3tm1Amc/Wnt3tm2Amc,Tg(Rarb-cre)1Mrc/0
Genetic Background: involves: 129S1/Sv * 129S7/SvEvBrd * 129X1/SvJ

 MP:0004510 myositis "inflammation of skeletal muscle; local accumulation of fluid, plasma proteins, and leukocytes in the striated muscle" [MESH:C05.651.594]
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Allelic Composition: Wnt3tm1Amc/Wnt3tm2Amc,Tg(Rarb-cre)1Mrc/0
Genetic Background: involves: 129S1/Sv * 129S7/SvEvBrd * 129X1/SvJ

 MP:0004769 abnormal synaptic vesicle morphology "any structural anomaly of the small, membrane bound sacs that contain various neurotransmitter molecules that are concentrated at pre-synaptic membranes and release the neurotransmitters by fusion of these vesicles with the presynaptic membrane, followed by exocytosis of their contents" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Col13a1tm3.1Pih/Col13a1tm3.1Pih
Genetic Background: involves: C57BL/6

 MP:0004835 abnormal miniature endplate potential "defect in the size or duration of spontaneous currents detected in PNS postsynaptic cells that occur in the absence of an excitatory impulse" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Col13a1tm3.1Pih/Col13a1tm3.1Pih
Genetic Background: involves: C57BL/6

 MP:0004836 abnormal synaptic acetylcholine release "aberrant secretion across synapses of the excitatory neurotransmitter found at neuromuscular junctions, autonomic ganglia, parasympathetic effector junctions, a subset of sympathetic effector junctions, and at many sites in the central nervous system" [MESH:National Library of Medicine_Medical Subject Headings]
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Allelic Composition: Col13a1tm3.1Pih/Col13a1tm3.1Pih
Genetic Background: involves: C57BL/6

 MP:0005165 increased susceptibility to injury "greater than the normal reaction to trauma, especially that by physical means" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
Show

Allelic Composition: Wnt3tm1Amc/Wnt3tm2Amc,Tg(Rarb-cre)1Mrc/0
Genetic Background: involves: 129S1/Sv * 129S7/SvEvBrd * 129X1/SvJ

 MP:0009402 decreased skeletal muscle fiber diameter "decreased width of the cross-sectional distance that extends from one lateral edge of a skeletal muscle fiber, through its center and to the opposite lateral edge" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Wnt3tm1Amc/Wnt3tm2Amc,Tg(Rarb-cre)1Mrc/0
Genetic Background: involves: 129S1/Sv * 129S7/SvEvBrd * 129X1/SvJ

 MP:0012106 impaired exercise endurance "impaired performance during controlled physical activity" [MGI:smb]
Show

Allelic Composition: Wnt3tm1Amc/Wnt3tm2Amc,Tg(Rarb-cre)1Mrc/0
Genetic Background: involves: 129S1/Sv * 129S7/SvEvBrd * 129X1/SvJ

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

1 s.

 
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