ENSMUSG00000059743


Mus musculus

Features
Gene ID: ENSMUSG00000059743
  
Biological name :Fdps
  
Synonyms : Farnesyl pyrophosphate synthase / Fdps / Q920E5
  
Possible biological names infered from orthology : farnesyl diphosphate synthase / P14324
  
Species: Mus musculus
  
Chr. number: 3
Strand: -1
Band: F1
Gene start: 89093588
Gene end: 89101959
  
Corresponding Affymetrix probe sets: 10499483 (MoGene1.0st)   1423418_at (Mouse Genome 430 2.0 Array)   1438150_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000142393
Ensembl peptide - ENSMUSP00000142770
Ensembl peptide - ENSMUSP00000142704
Ensembl peptide - ENSMUSP00000142669
Ensembl peptide - ENSMUSP00000080531
NCBI entrez gene - 110196     See in Manteia.
MGI - MGI:104888
RefSeq - NM_134469
RefSeq - NM_001253751
RefSeq Peptide - NP_001240680
RefSeq Peptide - NP_608219
swissprot - Q920E5
swissprot - A0A0G2JE82
swissprot - A0A0G2JDJ5
swissprot - Q4FJN9
swissprot - A0A0G2JEB3
Ensembl - ENSMUSG00000059743
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 fdpsENSDARG00000040890Danio rerio
 FDPSENSGALG00000028880Gallus gallus
 FDPSENSG00000160752Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR000092  Polyprenyl synthetase
 IPR008949  Isoprenoid synthase domain superfamily
 IPR033749  Polyprenyl synthetase, conserved site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006629 lipid metabolic process IEA
 biological_processGO:0006694 steroid biosynthetic process IEA
 biological_processGO:0006695 cholesterol biosynthetic process IEA
 biological_processGO:0008202 steroid metabolic process IEA
 biological_processGO:0008203 cholesterol metabolic process IEA
 biological_processGO:0008299 isoprenoid biosynthetic process IEA
 biological_processGO:0016126 sterol biosynthetic process IEA
 biological_processGO:0033384 geranyl diphosphate biosynthetic process IEA
 biological_processGO:0045337 farnesyl diphosphate biosynthetic process IEA
 cellular_componentGO:0005654 nucleoplasm ISO
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005739 mitochondrion IDA
 cellular_componentGO:0005829 cytosol ISO
 molecular_functionGO:0004161 dimethylallyltranstransferase activity IBA
 molecular_functionGO:0004337 geranyltranstransferase activity IBA
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
Cholesterol biosynthesis


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSMUSG00000059743 Fdps / Q920E5 / Farnesyl pyrophosphate synthase / P14324* / farnesyl diphosphate synthase*  / complex






 

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contact: otassy@igbmc.fr