ENSMUSG00000060733


Mus musculus

Features
Gene ID: ENSMUSG00000060733
  
Biological name :Ipmk
  
Synonyms : Ipmk / Mus musculus inositol polyphosphate multikinase (Ipmk), transcript variant 2, mRNA. / Q7TT16
  
Possible biological names infered from orthology : inositol polyphosphate multikinase / Q8NFU5
  
Species: Mus musculus
  
Chr. number: 10
Strand: 1
Band: B5.3
Gene start: 71347763
Gene end: 71433327
  
Corresponding Affymetrix probe sets: 10363894 (MoGene1.0st)   1430031_at (Mouse Genome 430 2.0 Array)   1436215_at (Mouse Genome 430 2.0 Array)   1437856_at (Mouse Genome 430 2.0 Array)   1456200_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000120612
Ensembl peptide - ENSMUSP00000078240
Ensembl peptide - ENSMUSP00000112568
Ensembl peptide - ENSMUSP00000113083
Ensembl peptide - ENSMUSP00000120073
NCBI entrez gene - 69718     See in Manteia.
MGI - MGI:1916968
RefSeq - XM_006514056
RefSeq - XM_011243555
RefSeq - NM_001347191
RefSeq - NM_027184
RefSeq Peptide - NP_001334120
RefSeq Peptide - NP_081460
swissprot - Q7TT16
swissprot - F6X767
swissprot - D3YWA2
Ensembl - ENSMUSG00000060733
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ipmkaENSDARG00000076699Danio rerio
 ipmkbENSDARG00000029291Danio rerio
 IPMKENSGALG00000002710Gallus gallus
 IPMKENSG00000151151Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Ip6k1 / Q6PD10 / Inositol hexakisphosphate kinase 1 / Q92551*ENSMUSG0000003259424
Ip6k2 / Q80V72 / Inositol hexakisphosphate kinase 2 / Q9UHH9*ENSMUSG0000003259923
Ip6k3 / Q8BWD2 / Inositol hexakisphosphate kinase 3 / Q96PC2*ENSMUSG0000002421021


Protein motifs (from Interpro)
Interpro ID Name
 IPR005522  Inositol polyphosphate kinase


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001841 neural tube formation IMP
 biological_processGO:0016310 phosphorylation IEA
 biological_processGO:0032958 inositol phosphate biosynthetic process IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005654 nucleoplasm IEA
 cellular_componentGO:0005730 nucleolus IEA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0000823 inositol-1,4,5-trisphosphate 6-kinase activity IEA
 molecular_functionGO:0000824 inositol tetrakisphosphate 3-kinase activity IMP
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0008440 inositol-1,4,5-trisphosphate 3-kinase activity IMP
 molecular_functionGO:0016301 kinase activity IEA
 molecular_functionGO:0016740 transferase activity IEA


Pathways (from Reactome)
Pathway description
Synthesis of IPs in the nucleus


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0000913 abnormal brain development "malformed or incomplete differentiation of the brain" [MGI:cls, J:49840]
Show

Allelic Composition: Foxp2tm1Bux/Foxp2+
Genetic Background: involves: C57BL/6

 MP:0000929 open neural tube "incomplete invagination and fusion of the neuroepithelial layer in early development" [MGI:CLS, J:53370, J:62571]
Show

Allelic Composition: Foxp2tm1Bux/Foxp2+
Genetic Background: involves: C57BL/6

 MP:0001698 reduced embryo size "smaller proportions of embryo compared to littermates" [J:61790]
Show

Allelic Composition: Foxp2tm1Bux/Foxp2+
Genetic Background: involves: C57BL/6

 MP:0001701 incomplete embryo turning "arrest of the axial rotation of the germ layers of the embryo during the primitive streak/early somite stage (E8.5-E9.5)" [J:62571]
Show

Allelic Composition: Foxp2tm1Bux/Foxp2+
Genetic Background: involves: C57BL/6

 MP:0003400 kinked neural tube "twists or kinks in the embryonic neural tube" [J:66514, anna:Anna Anagnostopoulos, Mouse Genome Informatics Curator]
Show

Allelic Composition: Foxp2tm1Bux/Foxp2+
Genetic Background: involves: C57BL/6

 MP:0003984 embryonic growth retardation "slow or limited development before birth" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Foxp2tm1Bux/Foxp2+
Genetic Background: involves: C57BL/6

 MP:0009657 failure of chorioallantoic fusion "failure to initiate and/or complete the formation of a highly vascularized extra-embryonic fetal membrane by fusion of the chorion and allantois" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Foxp2tm1Bux/Foxp2+
Genetic Background: involves: C57BL/6

 MP:0011098 complete embryonic lethality during organogenesis "death of all organisms of a given genotype in a population between embryo turning and the completion of organogenesis (Mus: E9 to less than E14)" [MGI:csmith]
Show

Allelic Composition: Foxp2tm1Bux/Foxp2+
Genetic Background: involves: C57BL/6

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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