ENSMUSG00000061723


Mus musculus

Features
Gene ID: ENSMUSG00000061723
  
Biological name :Tnnt3
  
Synonyms : Tnnt3 / troponin T3, skeletal, fast
  
Possible biological names infered from orthology : P45378 / troponin T3, fast skeletal type
  
Species: Mus musculus
  
Chr. number: 7
Strand: 1
Band: F5
Gene start: 142498836
Gene end: 142516009
  
Corresponding Affymetrix probe sets: 10559221 (MoGene1.0st)   1450118_a_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000101572
Ensembl peptide - ENSMUSP00000101570
Ensembl peptide - ENSMUSP00000101573
Ensembl peptide - ENSMUSP00000137111
Ensembl peptide - ENSMUSP00000136278
Ensembl peptide - ENSMUSP00000127854
Ensembl peptide - ENSMUSP00000116223
Ensembl peptide - ENSMUSP00000116087
Ensembl peptide - ENSMUSP00000101578
Ensembl peptide - ENSMUSP00000101577
Ensembl peptide - ENSMUSP00000101575
Ensembl peptide - ENSMUSP00000101574
Ensembl peptide - ENSMUSP00000073815
Ensembl peptide - ENSMUSP00000077587
Ensembl peptide - ENSMUSP00000101561
Ensembl peptide - ENSMUSP00000101562
Ensembl peptide - ENSMUSP00000101563
Ensembl peptide - ENSMUSP00000101564
Ensembl peptide - ENSMUSP00000101565
Ensembl peptide - ENSMUSP00000101566
Ensembl peptide - ENSMUSP00000101567
Ensembl peptide - ENSMUSP00000101568
Ensembl peptide - ENSMUSP00000101569
NCBI entrez gene - 21957     See in Manteia.
MGI - MGI:109550
RefSeq - XM_006508582
RefSeq - XM_006508551
RefSeq - XM_006508553
RefSeq - XM_006508557
RefSeq - XM_006508558
RefSeq - XM_006508561
RefSeq - XM_006508562
RefSeq - XM_006508563
RefSeq - XM_006508567
RefSeq - XM_006508569
RefSeq - XM_006508570
RefSeq - XM_006508571
RefSeq - XM_006508572
RefSeq - XM_006508573
RefSeq - XM_006508575
RefSeq - XM_006508576
RefSeq - XM_006508577
RefSeq - XM_006508584
RefSeq - XM_006508585
RefSeq - XM_006508586
RefSeq - XM_006508587
RefSeq - XM_006508588
RefSeq - XM_006508589
RefSeq - XM_006508590
RefSeq - XM_006508591
RefSeq - XM_006508592
RefSeq - XM_006508593
RefSeq - XM_006508594
RefSeq - XM_006508595
RefSeq - XM_006508596
RefSeq - XM_017322115
RefSeq - XM_017322116
RefSeq - XM_017322117
RefSeq - XM_017322118
RefSeq - XM_017322119
RefSeq - XM_017322120
RefSeq - XM_017322121
RefSeq - NM_001163664
RefSeq - NM_001163665
RefSeq - NM_001163666
RefSeq - NM_001163667
RefSeq - NM_001163668
RefSeq - NM_001163669
RefSeq - NM_001163670
RefSeq - NM_001347546
RefSeq - NM_001347547
RefSeq - NM_001347548
RefSeq - NM_001347549
RefSeq - NM_001347550
RefSeq - NM_001347551
RefSeq - NM_001347552
RefSeq - NM_011620
RefSeq - XM_006508542
RefSeq - XM_006508543
RefSeq - XM_006508546
RefSeq - XM_006508547
RefSeq - XM_006508550
RefSeq Peptide - NP_001334480
RefSeq Peptide - NP_001334481
RefSeq Peptide - NP_035750
RefSeq Peptide - NP_001334477
RefSeq Peptide - NP_001334478
RefSeq Peptide - NP_001334479
RefSeq Peptide - NP_001157136
RefSeq Peptide - NP_001157137
RefSeq Peptide - NP_001157138
RefSeq Peptide - NP_001157139
RefSeq Peptide - NP_001157140
RefSeq Peptide - NP_001157141
RefSeq Peptide - NP_001157142
RefSeq Peptide - NP_001334475
RefSeq Peptide - NP_001334476
swissprot - A0A0R4J1A8
swissprot - Z4YKG3
swissprot - Z4YKG8
swissprot - Z4YKH8
swissprot - Z4YNB2
swissprot - Z4YJU0
swissprot - Z4YKD9
swissprot - A2A6J1
swissprot - A2A6J0
swissprot - A2A6I8
swissprot - A2A6I5
swissprot - A2A6I3
swissprot - A2A6I0
swissprot - A2A6H6
swissprot - A0A0R4J1B1
swissprot - F6RL36
swissprot - J3QP61
swissprot - A0A0R4J1B0
swissprot - A2A6J2
swissprot - Z4YKE7
swissprot - Z4YKF8
Ensembl - ENSMUSG00000061723
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 tnnt3aENSDARG00000030270Danio rerio
 tnnt3bENSDARG00000068457Danio rerio
 TNNT3ENSGALG00000006572Gallus gallus
 TNNT3ENSG00000130595Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Tnnt1 / O88346 / troponin T1, skeletal, slow / P13805* / troponin T1, slow skeletal type*ENSMUSG0000006417958
Tnnt2 / P50752 / Troponin T, cardiac muscle / P45379* / troponin T2, cardiac type*ENSMUSG0000002641455


Protein motifs (from Interpro)
Interpro ID Name
 IPR001978  Troponin
 IPR027707  Troponin T
 IPR027708  Troponin T, fast skeletal muscle


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0003009 skeletal muscle contraction IEA
 biological_processGO:0006937 regulation of muscle contraction IEA
 biological_processGO:0006942 regulation of striated muscle contraction IEA
 biological_processGO:0043462 regulation of ATPase activity IEA
 cellular_componentGO:0005861 troponin complex IEA
 molecular_functionGO:0003779 actin binding IEA
 molecular_functionGO:0005523 tropomyosin binding IEA
 molecular_functionGO:0030172 troponin C binding IEA
 molecular_functionGO:0030899 calcium-dependent ATPase activity IEA
 molecular_functionGO:0031013 troponin I binding IEA
 molecular_functionGO:0048306 calcium-dependent protein binding IEA


Pathways (from Reactome)
Pathway description
Striated Muscle Contraction


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0000533 kidney hemorrhage "bleeding in the organ of excretion" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, tc:Teresa Chu , Mouse Genome Informatics Curator]
Show

Allelic Composition: Hprttm1(CMV-GFP)Nat/Y
Genetic Background: involves: 129P2/OlaHsd * C57BL/6

 MP:0000547 short limbs "reduced average length of the extremities" [MGI:CLS, J:61509]
Show

Allelic Composition: Hprttm1(CMV-GFP)Nat/Y
Genetic Background: involves: 129P2/OlaHsd * C57BL/6

 MP:0000761 thin diaphragm muscle "reduced thickness of the diaphragm muscle" [MGI:CLS, J:60159]
Show

Allelic Composition: Hprttm1(CMV-GFP)Nat/Y
Genetic Background: involves: 129P2/OlaHsd * C57BL/6

 MP:0001262 decreased body weight "lower than normal average weight " [J:61295]
Show

Allelic Composition: Hprttm1(CMV-GFP)Nat/Y
Genetic Background: involves: 129P2/OlaHsd * C57BL/6

 MP:0001265 reduced body size "smaller than average body weight, height and/or length of an organism compared to controls" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, J:23170]
Show

Allelic Composition: Hprttm1(CMV-GFP)Nat/Y
Genetic Background: involves: 129P2/OlaHsd * C57BL/6

 MP:0001732 postnatal growth retardation "slow or limited development after birth " [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
Show

Allelic Composition: Hprttm1(CMV-GFP)Nat/Y
Genetic Background: involves: 129P2/OlaHsd * C57BL/6

 MP:0002896 abnormal bone mineralization "defect in the process by which minerals are deposited into bone" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Hprttm1(CMV-GFP)Nat/Y
Genetic Background: involves: 129P2/OlaHsd * C57BL/6

 MP:0003888 liver hemorrhage "bleeding within the liver" [anna:Anna Anagnostopoulos, Mouse Genome Informatics Curator]
Show

Allelic Composition: Hprttm1(CMV-GFP)Nat/Y
Genetic Background: involves: 129P2/OlaHsd * C57BL/6

 MP:0004200 reduced fetal size "smaller proportions of a fetus compared to littermates (sensu Mus: from E14 through birth)" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Hprttm1(CMV-GFP)Nat/Y
Genetic Background: involves: 129P2/OlaHsd * C57BL/6

Allelic Composition: Tnnt3tm2a(KOMP)Wtsi/Tnnt3tm2a(KOMP)Wtsi
Genetic Background: involves: C57BL/6N

 MP:0006396 decreased long bone epiphyseal plate size "reduced size of the cartilaginous center of ossification on the long bones permitting growth of the bone in both directions during development" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Hprttm1(CMV-GFP)Nat/Y
Genetic Background: involves: 129P2/OlaHsd * C57BL/6

 MP:0011087 complete neonatal lethality "death of all organisms of a given genotype in a population within the neonatal period after birth (Mus: P0)" [MGI:csmith]
Show

Allelic Composition: Tnnt3tm2a(KOMP)Wtsi/Tnnt3tm2a(KOMP)Wtsi
Genetic Background: involves: C57BL/6N

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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