ENSMUSG00000063903


Mus musculus

Features
Gene ID: ENSMUSG00000063903
  
Biological name :Klk1
  
Synonyms : Kallikrein-1 / Klk1 / P15947
  
Possible biological names infered from orthology : kallikrein related peptidase 2 / kallikrein related peptidase 3 / KLK2 / KLK3 / P06870 / P07288 / P20151
  
Species: Mus musculus
  
Chr. number: 7
Strand: 1
Band: B3
Gene start: 44225360
Gene end: 44229618
  
Corresponding Affymetrix probe sets: 10552546 (MoGene1.0st)   1415837_at (Mouse Genome 430 2.0 Array)   1448107_x_at (Mouse Genome 430 2.0 Array)   1455977_x_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000146057
Ensembl peptide - ENSMUSP00000074659
NCBI entrez gene - 16612     See in Manteia.
MGI - MGI:102850
RefSeq - NM_001320331
RefSeq - NM_001320332
RefSeq - NM_010639
RefSeq Peptide - NP_034769
RefSeq Peptide - NP_001307260
RefSeq Peptide - NP_001307261
swissprot - P15947
swissprot - A0A0U1RPN5
swissprot - A0A0B6VSQ6
Ensembl - ENSMUSG00000063903
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 KLK1ENSG00000167748Homo sapiens
 KLK2ENSG00000167751Homo sapiens
 KLK3ENSG00000142515Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Klk1b5 / P15945 / Kallikrein 1-related peptidase b5 / KLK1* / KLK3* / KLK2* / P06870* / P07288* / P20151* / kallikrein 1* / kallikrein related peptidase 3* / kallikrein related peptidase 2*ENSMUSG0000006651291
Klk1b4 / P00757 / Kallikrein 1-related peptidase-like b4 / KLK1* / KLK3* / KLK2* / P20151* / P06870* / P07288* / kallikrein 1* / kallikrein related peptidase 3* / kallikrein related peptidase 2*ENSMUSG0000006651382
Klk1b3 / P00756 / Kallikrein 1-related peptidase b3 Nerve growth factor gamma chain 1 Nerve growth factor gamma chain 2 / KLK1* / KLK3* / KLK2* / P20151* / P06870* / P07288* / kallikrein 1*...ENSMUSG0000006651579
Q61759 / Klk1b21 / Kallikrein 1-related peptidase b21 / KLK2* / KLK1* / KLK3* / P06870* / P07288* / P20151* / kallikrein 1* / kallikrein related peptidase 2* / kallikrein related peptidase 3*ENSMUSG0000006651678
Klk1b9 / P15949 / Kallikrein 1-related peptidase b9 / KLK1* / KLK3* / KLK2* / P06870* / P07288* / P20151* / kallikrein 1* / kallikrein related peptidase 3* / kallikrein related peptidase 2*ENSMUSG0000005904276
P15946 / Klk1b11 / Kallikrein 1-related peptidase b11 / KLK2* / KLK3* / KLK1* / P20151* / P06870* / P07288* / kallikrein 1* / kallikrein related peptidase 2* / kallikrein related peptidase 3*ENSMUSG0000004448576
P15948 / Klk1b22 / kallikrein 1-related peptidase b22 / KLK2* / KLK3* / KLK1* / P20151* / P06870* / P07288* / kallikrein 1* / kallikrein related peptidase 2* / kallikrein related peptidase 3*ENSMUSG0000006017775
Klk1b1 / P00755 / Kallikrein 1-related peptidase b1 / KLK1* / KLK3* / KLK2* / P20151* / P06870* / P07288* / kallikrein 1* / kallikrein related peptidase 3* / kallikrein related peptidase 2*ENSMUSG0000006313375
Q61754 / Klk1b24 / Kallikrein 1-related peptidase b24 / KLK2* / KLK1* / KLK3* / P06870* / P07288* / P20151* / kallikrein 1* / kallikrein related peptidase 2* / kallikrein related peptidase 3*ENSMUSG0000006371375
Q9JM71 / Klk1b27 / Kallikrein 1-related peptidase b27 / KLK2* / KLK1* / KLK3* / P06870* / P07288* / P20151* / kallikrein 1* / kallikrein related peptidase 2* / kallikrein related peptidase 3*ENSMUSG0000006317774
P36369 / Klk1b26 / Kallikrein 1-related peptidase b26 / KLK2* / KLK1* / KLK3* / P06870* / P07288* / P20151* / kallikrein 1* / kallikrein related peptidase 2* / kallikrein related peptidase 3*ENSMUSG0000005371973
Klk1b8 / P07628 / Kallikrein 1-related peptidase b8 / KLK1* / KLK3* / KLK2* / P06870* / P07288* / P20151* / kallikrein 1* / kallikrein related peptidase 3* / kallikrein related peptidase 2*ENSMUSG0000006308972
P04071 / Klk1b16 / Kallikrein 1-related peptidase b16 / KLK2* / KLK3* / KLK1* / P20151* / P06870* / P07288* / kallikrein 1* / kallikrein related peptidase 2* / kallikrein related peptidase 3*ENSMUSG0000003896870


Protein motifs (from Interpro)
Interpro ID Name
 IPR001254  Serine proteases, trypsin domain
 IPR001314  Peptidase S1A, chymotrypsin family
 IPR009003  Peptidase S1, PA clan
 IPR018114  Serine proteases, trypsin family, histidine active site
 IPR033116  Serine proteases, trypsin family, serine active site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006508 proteolysis IEA
 cellular_componentGO:0005615 extracellular space ISO
 molecular_functionGO:0004175 endopeptidase activity ISO
 molecular_functionGO:0004252 serine-type endopeptidase activity IEA
 molecular_functionGO:0008233 peptidase activity IEA
 molecular_functionGO:0008236 serine-type peptidase activity IEA
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0016811 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides ISO


Pathways (from Reactome)
Pathway description
Activation of Matrix Metalloproteinases
Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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