ENSMUSG00000066513


Mus musculus

Features
Gene ID: ENSMUSG00000066513
  
Biological name :Klk1b4
  
Synonyms : Kallikrein 1-related peptidase-like b4 / Klk1b4 / P00757
  
Possible biological names infered from orthology : kallikrein 1 / kallikrein related peptidase 2 / kallikrein related peptidase 3 / KLK1 / KLK2 / KLK3 / P06870 / P07288 / P20151
  
Species: Mus musculus
  
Chr. number: 7
Strand: 1
Band: B3
Gene start: 44207435
Gene end: 44211754
  
Corresponding Affymetrix probe sets: 10552613 (MoGene1.0st)   1421372_at (Mouse Genome 430 2.0 Array)   1450222_x_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000076576
NCBI entrez gene - 18048     See in Manteia.
MGI - MGI:97320
RefSeq - NM_010915
RefSeq Peptide - NP_035045
swissprot - A0A1R3UGK0
swissprot - P00757
Ensembl - ENSMUSG00000066513
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 KLK1ENSG00000167748Homo sapiens
 KLK2ENSG00000167751Homo sapiens
 KLK3ENSG00000142515Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Klk1 / P15947 / Kallikrein-1 / KLK2* / KLK3* / P20151* / P06870* / P07288* / kallikrein related peptidase 2* / kallikrein related peptidase 3*ENSMUSG0000006390384
Klk1b5 / P15945 / Kallikrein 1-related peptidase b5 / KLK1* / KLK3* / KLK2* / P06870* / P07288* / P20151* / kallikrein 1* / kallikrein related peptidase 3* / kallikrein related peptidase 2*ENSMUSG0000006651283
Klk1b3 / P00756 / Kallikrein 1-related peptidase b3 Nerve growth factor gamma chain 1 Nerve growth factor gamma chain 2 / KLK1* / KLK3* / KLK2* / P20151* / P06870* / P07288* / kallikrein 1*...ENSMUSG0000006651580
Klk1b9 / P15949 / Kallikrein 1-related peptidase b9 / KLK1* / KLK3* / KLK2* / P06870* / P07288* / P20151* / kallikrein 1* / kallikrein related peptidase 3* / kallikrein related peptidase 2*ENSMUSG0000005904277
P15946 / Klk1b11 / Kallikrein 1-related peptidase b11 / KLK2* / KLK3* / KLK1* / P20151* / P06870* / P07288* / kallikrein 1* / kallikrein related peptidase 2* / kallikrein related peptidase 3*ENSMUSG0000004448577
Klk1b1 / P00755 / Kallikrein 1-related peptidase b1 / KLK1* / KLK3* / KLK2* / P20151* / P06870* / P07288* / kallikrein 1* / kallikrein related peptidase 3* / kallikrein related peptidase 2*ENSMUSG0000006313377
Q61754 / Klk1b24 / Kallikrein 1-related peptidase b24 / KLK2* / KLK1* / KLK3* / P06870* / P07288* / P20151* / kallikrein 1* / kallikrein related peptidase 2* / kallikrein related peptidase 3*ENSMUSG0000006371376
Q61759 / Klk1b21 / Kallikrein 1-related peptidase b21 / KLK2* / KLK1* / KLK3* / P06870* / P07288* / P20151* / kallikrein 1* / kallikrein related peptidase 2* / kallikrein related peptidase 3*ENSMUSG0000006651675
Q9JM71 / Klk1b27 / Kallikrein 1-related peptidase b27 / KLK2* / KLK1* / KLK3* / P06870* / P07288* / P20151* / kallikrein 1* / kallikrein related peptidase 2* / kallikrein related peptidase 3*ENSMUSG0000006317774
P15948 / Klk1b22 / kallikrein 1-related peptidase b22 / KLK2* / KLK3* / KLK1* / P20151* / P06870* / P07288* / kallikrein 1* / kallikrein related peptidase 2* / kallikrein related peptidase 3*ENSMUSG0000006017774
P36369 / Klk1b26 / Kallikrein 1-related peptidase b26 / KLK2* / KLK1* / KLK3* / P06870* / P07288* / P20151* / kallikrein 1* / kallikrein related peptidase 2* / kallikrein related peptidase 3*ENSMUSG0000005371972
Klk1b8 / P07628 / Kallikrein 1-related peptidase b8 / KLK1* / KLK3* / KLK2* / P06870* / P07288* / P20151* / kallikrein 1* / kallikrein related peptidase 3* / kallikrein related peptidase 2*ENSMUSG0000006308971
P04071 / Klk1b16 / Kallikrein 1-related peptidase b16 / KLK2* / KLK3* / KLK1* / P20151* / P06870* / P07288* / kallikrein 1* / kallikrein related peptidase 2* / kallikrein related peptidase 3*ENSMUSG0000003896868


Protein motifs (from Interpro)
Interpro ID Name
 IPR001254  Serine proteases, trypsin domain
 IPR001314  Peptidase S1A, chymotrypsin family
 IPR009003  Peptidase S1, PA clan
 IPR018114  Serine proteases, trypsin family, histidine active site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006508 proteolysis IEA
 biological_processGO:0007264 small GTPase mediated signal transduction IDA
 biological_processGO:0010469 regulation of signaling receptor activity IEA
 biological_processGO:0043552 positive regulation of phosphatidylinositol 3-kinase activity IDA
 cellular_componentGO:0005615 extracellular space ISO
 cellular_componentGO:0005622 intracellular IEA
 molecular_functionGO:0004175 endopeptidase activity ISO
 molecular_functionGO:0004252 serine-type endopeptidase activity ISO
 molecular_functionGO:0005057 obsolete signal transducer activity, downstream of receptor IDA
 molecular_functionGO:0008083 growth factor activity IEA
 molecular_functionGO:0016811 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides ISO
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
Activation of Matrix Metalloproteinases
Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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