ENSMUSG00000066515


Mus musculus

Features
Gene ID: ENSMUSG00000066515
  
Biological name :Klk1b3
  
Synonyms : Kallikrein 1-related peptidase b3 Nerve growth factor gamma chain 1 Nerve growth factor gamma chain 2 / Klk1b3 / P00756
  
Possible biological names infered from orthology : kallikrein 1 / kallikrein related peptidase 2 / kallikrein related peptidase 3 / KLK1 / KLK2 / KLK3 / P06870 / P07288 / P20151
  
Species: Mus musculus
  
Chr. number: 7
Strand: 1
Band: B3
Gene start: 44198191
Gene end: 44202352
  
Corresponding Affymetrix probe sets: 10552546 (MoGene1.0st)   10552608 (MoGene1.0st)   1427380_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000082577
NCBI entrez gene - 18050     See in Manteia.
MGI - MGI:97322
RefSeq - NM_008693
RefSeq Peptide - NP_032719
swissprot - A0A1R3UHM9
swissprot - P00756
Ensembl - ENSMUSG00000066515
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 KLK1ENSG00000167748Homo sapiens
 KLK2ENSG00000167751Homo sapiens
 KLK3ENSG00000142515Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Klk1b9 / P15949 / Kallikrein 1-related peptidase b9 / KLK1* / KLK3* / KLK2* / P06870* / P07288* / P20151* / kallikrein 1* / kallikrein related peptidase 3* / kallikrein related peptidase 2*ENSMUSG0000005904285
Klk1b5 / P15945 / Kallikrein 1-related peptidase b5 / KLK1* / KLK3* / KLK2* / P06870* / P07288* / P20151* / kallikrein 1* / kallikrein related peptidase 3* / kallikrein related peptidase 2*ENSMUSG0000006651281
Klk1b1 / P00755 / Kallikrein 1-related peptidase b1 / KLK1* / KLK3* / KLK2* / P20151* / P06870* / P07288* / kallikrein 1* / kallikrein related peptidase 3* / kallikrein related peptidase 2*ENSMUSG0000006313381
P15946 / Klk1b11 / Kallikrein 1-related peptidase b11 / KLK2* / KLK3* / KLK1* / P20151* / P06870* / P07288* / kallikrein 1* / kallikrein related peptidase 2* / kallikrein related peptidase 3*ENSMUSG0000004448580
Q61759 / Klk1b21 / Kallikrein 1-related peptidase b21 / KLK2* / KLK1* / KLK3* / P06870* / P07288* / P20151* / kallikrein 1* / kallikrein related peptidase 2* / kallikrein related peptidase 3*ENSMUSG0000006651679
Klk1b4 / P00757 / Kallikrein 1-related peptidase-like b4 / KLK1* / KLK3* / KLK2* / P20151* / P06870* / P07288* / kallikrein 1* / kallikrein related peptidase 3* / kallikrein related peptidase 2*ENSMUSG0000006651379
P15948 / Klk1b22 / kallikrein 1-related peptidase b22 / KLK2* / KLK3* / KLK1* / P20151* / P06870* / P07288* / kallikrein 1* / kallikrein related peptidase 2* / kallikrein related peptidase 3*ENSMUSG0000006017779
Klk1 / P15947 / Kallikrein-1 / KLK2* / KLK3* / P20151* / P06870* / P07288* / kallikrein related peptidase 2* / kallikrein related peptidase 3*ENSMUSG0000006390379
Q9JM71 / Klk1b27 / Kallikrein 1-related peptidase b27 / KLK2* / KLK1* / KLK3* / P06870* / P07288* / P20151* / kallikrein 1* / kallikrein related peptidase 2* / kallikrein related peptidase 3*ENSMUSG0000006317778
Q61754 / Klk1b24 / Kallikrein 1-related peptidase b24 / KLK2* / KLK1* / KLK3* / P06870* / P07288* / P20151* / kallikrein 1* / kallikrein related peptidase 2* / kallikrein related peptidase 3*ENSMUSG0000006371377
Klk1b8 / P07628 / Kallikrein 1-related peptidase b8 / KLK1* / KLK3* / KLK2* / P06870* / P07288* / P20151* / kallikrein 1* / kallikrein related peptidase 3* / kallikrein related peptidase 2*ENSMUSG0000006308974
P36369 / Klk1b26 / Kallikrein 1-related peptidase b26 / KLK2* / KLK1* / KLK3* / P06870* / P07288* / P20151* / kallikrein 1* / kallikrein related peptidase 2* / kallikrein related peptidase 3*ENSMUSG0000005371974
P04071 / Klk1b16 / Kallikrein 1-related peptidase b16 / KLK2* / KLK3* / KLK1* / P20151* / P06870* / P07288* / kallikrein 1* / kallikrein related peptidase 2* / kallikrein related peptidase 3*ENSMUSG0000003896872


Protein motifs (from Interpro)
Interpro ID Name
 IPR001254  Serine proteases, trypsin domain
 IPR001314  Peptidase S1A, chymotrypsin family
 IPR009003  Peptidase S1, PA clan
 IPR018114  Serine proteases, trypsin family, histidine active site
 IPR033116  Serine proteases, trypsin family, serine active site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006508 proteolysis IEA
 biological_processGO:0007165 signal transduction IEA
 biological_processGO:0010469 regulation of signaling receptor activity IEA
 cellular_componentGO:0005615 extracellular space ISO
 molecular_functionGO:0004175 endopeptidase activity ISO
 molecular_functionGO:0004252 serine-type endopeptidase activity ISO
 molecular_functionGO:0005057 obsolete signal transducer activity, downstream of receptor IDA
 molecular_functionGO:0008083 growth factor activity IEA
 molecular_functionGO:0008233 peptidase activity IEA
 molecular_functionGO:0008236 serine-type peptidase activity IEA
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0016811 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides ISO
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
Activation of Matrix Metalloproteinases
Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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