ENSMUSG00000064090


Mus musculus

Features
Gene ID: ENSMUSG00000064090
  
Biological name :Vrk2
  
Synonyms : Q8BN21 / vaccinia related kinase 2 / Vrk2
  
Possible biological names infered from orthology : Q86Y07
  
Species: Mus musculus
  
Chr. number: 11
Strand: -1
Band: A3.3
Gene start: 26471322
Gene end: 26593999
  
Corresponding Affymetrix probe sets: 10384782 (MoGene1.0st)   1451929_a_at (Mouse Genome 430 2.0 Array)   1453343_s_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000077471
Ensembl peptide - ENSMUSP00000105130
Ensembl peptide - ENSMUSP00000119928
NCBI entrez gene - 69922     See in Manteia.
MGI - MGI:1917172
RefSeq - XM_017314748
RefSeq - NM_001252447
RefSeq - NM_027260
RefSeq - XM_006514801
RefSeq - XM_011243748
RefSeq Peptide - NP_001239376
RefSeq Peptide - NP_081536
swissprot - Q8BN21
swissprot - Q5SP86
Ensembl - ENSMUSG00000064090
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 vrk2ENSDARG00000021547Danio rerio
 VRK2ENSGALG00000032770Gallus gallus
 VRK2ENSG00000028116Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Vrk1 / Q80X41 / vaccinia related kinase 1 / Q99986*ENSMUSG0000002111538
Vrk3 / Q8K3G5 / vaccinia related kinase 3 / Q8IV63*ENSMUSG0000000220525
Q8BVP5 / Csnk1g2 / Casein kinase I isoform gamma-2 / P78368* / casein kinase 1 gamma 2*ENSMUSG0000000334520
Q8C4X2 / Csnk1g3 / Casein kinase I isoform gamma-3 / Q9Y6M4* / casein kinase 1 gamma 3*ENSMUSG0000007356320
Q8BTH8 / Csnk1g1 / Casein kinase I isoform gamma-1 / Q9HCP0* / casein kinase 1 gamma 1*ENSMUSG0000003238420


Protein motifs (from Interpro)
Interpro ID Name
 IPR000719  Protein kinase domain
 IPR008271  Serine/threonine-protein kinase, active site
 IPR011009  Protein kinase-like domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006468 protein phosphorylation IDA
 biological_processGO:0008360 regulation of cell shape IBA
 biological_processGO:0016310 phosphorylation IEA
 biological_processGO:0018105 peptidyl-serine phosphorylation IBA
 biological_processGO:0034599 cellular response to oxidative stress IEA
 biological_processGO:0043408 regulation of MAPK cascade IEA
 biological_processGO:0046777 protein autophosphorylation IEA
 biological_processGO:2000659 regulation of interleukin-1-mediated signaling pathway IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005737 cytoplasm ISS
 cellular_componentGO:0005739 mitochondrion IEA
 cellular_componentGO:0005783 endoplasmic reticulum ISO
 cellular_componentGO:0005789 endoplasmic reticulum membrane ISO
 cellular_componentGO:0016020 membrane IDA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0031966 mitochondrial membrane ISO
 cellular_componentGO:0032991 protein-containing complex IEA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0004672 protein kinase activity IEA
 molecular_functionGO:0004674 protein serine/threonine kinase activity ISO
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0016301 kinase activity IEA
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0019901 protein kinase binding IEA
 molecular_functionGO:0019904 protein domain specific binding IEA


Pathways (from Reactome)
Pathway description
Initiation of Nuclear Envelope Reformation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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