ENSG00000028116


Homo sapiens

Features
Gene ID: ENSG00000028116
  
Biological name :VRK2
  
Synonyms : Q86Y07 / vaccinia related kinase 2 / VRK2
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 2
Strand: 1
Band: p16.1
Gene start: 57907651
Gene end: 58159920
  
Corresponding Affymetrix probe sets: 205126_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000404156
Ensembl peptide - ENSP00000402375
Ensembl peptide - ENSP00000404961
Ensembl peptide - ENSP00000408002
Ensembl peptide - ENSP00000342381
Ensembl peptide - ENSP00000398323
Ensembl peptide - ENSP00000400006
NCBI entrez gene - 7444     See in Manteia.
OMIM - 602169
RefSeq - XM_017004866
RefSeq - XM_006712091
RefSeq - XM_006712092
RefSeq - XM_006712093
RefSeq - XM_011533092
RefSeq - XM_017004858
RefSeq - XM_017004859
RefSeq - XM_017004860
RefSeq - XM_017004861
RefSeq - XM_017004862
RefSeq - XM_017004863
RefSeq - XM_017004864
RefSeq - XM_017004865
RefSeq - NM_001130480
RefSeq - NM_001130481
RefSeq - NM_001130482
RefSeq - NM_001130483
RefSeq - NM_001288836
RefSeq - NM_001288837
RefSeq - NM_001288838
RefSeq - NM_001288839
RefSeq - NM_006296
RefSeq - XM_005264540
RefSeq - XM_006712090
RefSeq Peptide - NP_001123953
RefSeq Peptide - NP_001123954
RefSeq Peptide - NP_001123955
RefSeq Peptide - NP_001275765
RefSeq Peptide - NP_001275766
RefSeq Peptide - NP_001275767
RefSeq Peptide - NP_001275768
RefSeq Peptide - NP_006287
RefSeq Peptide - NP_001123952
swissprot - E7ERS5
swissprot - E9PBU1
swissprot - Q86Y07
Ensembl - ENSG00000028116
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 vrk2ENSDARG00000021547Danio rerio
 VRK2ENSGALG00000032770Gallus gallus
 Vrk2ENSMUSG00000064090Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
VRK1 / Q99986 / vaccinia related kinase 1ENSG0000010074937
VRK3 / Q8IV63 / vaccinia related kinase 3ENSG0000010505323
Q9HCP0 / CSNK1G1 / casein kinase 1 gamma 1ENSG0000016911819
P78368 / CSNK1G2 / casein kinase 1 gamma 2ENSG0000013327519
Q9Y6M4 / CSNK1G3 / casein kinase 1 gamma 3ENSG0000015129219


Protein motifs (from Interpro)
Interpro ID Name
 IPR000719  Protein kinase domain
 IPR008271  Serine/threonine-protein kinase, active site
 IPR011009  Protein kinase-like domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006468 protein phosphorylation TAS
 biological_processGO:0008360 regulation of cell shape IBA
 biological_processGO:0016032 viral process IEA
 biological_processGO:0016310 phosphorylation IEA
 biological_processGO:0018105 peptidyl-serine phosphorylation IBA
 biological_processGO:0034599 cellular response to oxidative stress IMP
 biological_processGO:0043408 regulation of MAPK cascade IMP
 biological_processGO:0046777 protein autophosphorylation IDA
 biological_processGO:2000659 regulation of interleukin-1-mediated signaling pathway IMP
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005739 mitochondrion IEA
 cellular_componentGO:0005783 endoplasmic reticulum IDA
 cellular_componentGO:0005789 endoplasmic reticulum membrane IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0031966 mitochondrial membrane IEA
 cellular_componentGO:0032991 protein-containing complex IDA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0004672 protein kinase activity IEA
 molecular_functionGO:0004674 protein serine/threonine kinase activity TAS
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0016301 kinase activity IEA
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0019901 protein kinase binding IDA
 molecular_functionGO:0019904 protein domain specific binding IDA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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