ENSG00000133275


Homo sapiens

Features
Gene ID: ENSG00000133275
  
Biological name :CSNK1G2
  
Synonyms : casein kinase 1 gamma 2 / CSNK1G2 / P78368
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 19
Strand: 1
Band: p13.3
Gene start: 1941149
Gene end: 1981338
  
Corresponding Affymetrix probe sets: 202573_at (Human Genome U133 Plus 2.0 Array)   202574_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000467214
Ensembl peptide - ENSP00000482716
Ensembl peptide - ENSP00000480929
Ensembl peptide - ENSP00000480185
Ensembl peptide - ENSP00000480052
Ensembl peptide - ENSP00000468637
Ensembl peptide - ENSP00000255641
Ensembl peptide - ENSP00000465106
NCBI entrez gene - 1455     See in Manteia.
OMIM - 602214
RefSeq - XM_017026298
RefSeq - NM_001319
RefSeq - XM_005259498
RefSeq - XM_005259499
RefSeq - XM_005259500
RefSeq - XM_005259501
RefSeq - XM_017026297
RefSeq Peptide - NP_001310
swissprot - P78368
swissprot - A0A087WWF5
swissprot - A0A087WW97
swissprot - A0A087WXD7
swissprot - K7EJC0
swissprot - K7EP38
swissprot - A0A087WZK4
swissprot - K7ESB6
Ensembl - ENSG00000133275
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 csnk1g2aENSDARG00000005458Danio rerio
 csnk1g2bENSDARG00000034056Danio rerio
 CSNK1G2ENSGALG00000027540Gallus gallus
 Q8BVP5ENSMUSG00000003345Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q9Y6M4 / CSNK1G3 / casein kinase 1 gamma 3ENSG0000015129284
Q9HCP0 / CSNK1G1 / casein kinase 1 gamma 1ENSG0000016911880
VRK1 / Q99986 / vaccinia related kinase 1ENSG0000010074924
VRK2 / Q86Y07 / vaccinia related kinase 2ENSG0000002811623
VRK3 / Q8IV63 / vaccinia related kinase 3ENSG0000010505320


Protein motifs (from Interpro)
Interpro ID Name
 IPR000719  Protein kinase domain
 IPR008271  Serine/threonine-protein kinase, active site
 IPR011009  Protein kinase-like domain superfamily
 IPR017441  Protein kinase, ATP binding site
 IPR022247  Casein kinase 1 gamma C-terminal


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006468 protein phosphorylation IEA
 biological_processGO:0006897 endocytosis IBA
 biological_processGO:0007165 signal transduction TAS
 biological_processGO:0008360 regulation of cell shape IBA
 biological_processGO:0016055 Wnt signaling pathway IBA
 biological_processGO:0016310 phosphorylation IEA
 biological_processGO:0018105 peptidyl-serine phosphorylation IDA
 biological_processGO:0030148 sphingolipid biosynthetic process TAS
 biological_processGO:0046777 protein autophosphorylation IEA
 cellular_componentGO:0005634 nucleus IBA
 cellular_componentGO:0005737 cytoplasm IBA
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0016020 membrane HDA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0000287 magnesium ion binding IEA
 molecular_functionGO:0004672 protein kinase activity IEA
 molecular_functionGO:0004674 protein serine/threonine kinase activity IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0016301 kinase activity IEA
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0042277 peptide binding IEA
 molecular_functionGO:0051219 phosphoprotein binding IEA


Pathways (from Reactome)
Pathway description
Sphingolipid de novo biosynthesis
Disassembly of the destruction complex and recruitment of AXIN to the membrane


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000113163 Q9Y5P4 / COL4A3BP / collagen type IV alpha 3 binding protein  / reaction






 

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