ENSMUSG00000067608


Mus musculus

Features
Gene ID: ENSMUSG00000067608
  
Biological name :Pcna-ps2
  
Synonyms : Pcna-ps2
  
Possible biological names infered from orthology : P12004 / PCNA / proliferating cell nuclear antigen
  
Species: Mus musculus
  
Chr. number: 19
Strand: 1
Band: A
Gene start: 9283238
Gene end: 9284494
  
Corresponding Affymetrix probe sets: 10461391 (MoGene1.0st)   10487930 (MoGene1.0st)   1417947_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000137596
MGI - MGI:97505
swissprot - A0A140T8V5
Ensembl - ENSMUSG00000067608
  
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 pcnaENSDARG00000054155Danio rerio
 PCNAENSGALG00000029292Gallus gallus
 PCNAENSG00000132646Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Pcna / P17918 / proliferating cell nuclear antigen / P12004*ENSMUSG0000002734299


Protein motifs (from Interpro)
Interpro ID Name
 IPR000730  Proliferating cell nuclear antigen, PCNA
 IPR022648  Proliferating cell nuclear antigen, PCNA, N-terminal
 IPR022649  Proliferating cell nuclear antigen, PCNA, C-terminal
 IPR022659  Proliferating cell nuclear antigen, PCNA, conserved site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006260 DNA replication IEA
 biological_processGO:0006275 regulation of DNA replication IEA
 cellular_componentGO:0005634 nucleus IEA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0030337 DNA polymerase processivity factor activity IEA


Pathways (from Reactome)
Pathway description
Translesion synthesis by REV1
Recognition of DNA damage by PCNA-containing replication complex
Translesion Synthesis by POLH
Polymerase switching on the C-strand of the telomere
Processive synthesis on the C-strand of the telomere
Telomere C-strand (Lagging Strand) Synthesis
Removal of the Flap Intermediate from the C-strand
SUMOylation of DNA replication proteins
Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)
PCNA-Dependent Long Patch Base Excision Repair
Translesion synthesis by POLK
Translesion synthesis by POLI
Termination of translesion DNA synthesis
HDR through Homologous Recombination (HRR)
Gap-filling DNA repair synthesis and ligation in GG-NER
Dual Incision in GG-NER
Dual incision in TC-NER
Gap-filling DNA repair synthesis and ligation in TC-NER
TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest
Polymerase switching
Removal of the Flap Intermediate
Processive synthesis on the lagging strand


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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