ENSMUSG00000068457


Mus musculus

Features
Gene ID: ENSMUSG00000068457
  
Biological name :Uty
  
Synonyms : ubiquitously transcribed tetratricopeptide repeat gene, Y chromosome / Uty
  
Possible biological names infered from orthology : O14607 / ubiquitously transcribed tetratricopeptide repeat containing, Y-linked
  
Species: Mus musculus
  
Chr. number: Y
Strand: -1
Band: A1
Gene start: 1096861
Gene end: 1245759
  
Corresponding Affymetrix probe sets: 10608107 (MoGene1.0st)   1422247_a_at (Mouse Genome 430 2.0 Array)   1426598_at (Mouse Genome 430 2.0 Array)   1457582_at (Mouse Genome 430 2.0 Array)   1459565_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000115113
Ensembl peptide - ENSMUSP00000114910
Ensembl peptide - ENSMUSP00000116372
Ensembl peptide - ENSMUSP00000122818
Ensembl peptide - ENSMUSP00000120069
Ensembl peptide - ENSMUSP00000119406
Ensembl peptide - ENSMUSP00000070012
Ensembl peptide - ENSMUSP00000114752
NCBI entrez gene - 22290     See in Manteia.
MGI - MGI:894810
RefSeq - XM_017318688
RefSeq - XM_006531590
RefSeq - XM_011248581
RefSeq - XM_011248582
RefSeq - XM_011248583
RefSeq - XM_011248584
RefSeq - XM_011248585
RefSeq - XM_011248586
RefSeq - XM_011248587
RefSeq - XM_011248589
RefSeq - XM_017318686
RefSeq - XM_017318687
RefSeq - NM_001326682
RefSeq - NM_001326683
RefSeq - NM_009484
RefSeq - XM_006531584
RefSeq - XM_006531587
RefSeq - XM_006531589
RefSeq Peptide - NP_033510
RefSeq Peptide - NP_001313611
RefSeq Peptide - NP_001313612
swissprot - F7BBC1
swissprot - G3X9F2
swissprot - E9Q504
swissprot - Q3UQE8
swissprot - D3Z2A3
swissprot - D6RFT4
swissprot - E9PWW8
swissprot - D6RJL0
Ensembl - ENSMUSG00000068457
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 kdm6aENSDARG00000061759Danio rerio
 ENSGALG00000016217Gallus gallus
 UTYENSG00000183878Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Kdm6a / O70546 / Lysine-specific demethylase 6A / O15550* / lysine demethylase 6A*ENSMUSG0000003736978
Kdm6b / Q5NCY0 / Lysine-specific demethylase 6B / O15054* / lysine demethylase 6B*ENSMUSG0000001847633


Protein motifs (from Interpro)
Interpro ID Name
 IPR003347  JmjC domain
 IPR011990  Tetratricopeptide-like helical domain superfamily
 IPR013026  Tetratricopeptide repeat-containing domain
 IPR019734  Tetratricopeptide repeat


Gene Ontology (GO)
TypeGO IDTermEv.Code
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0005515 protein binding IEA


Pathways (from Reactome)
Pathway description
HDMs demethylate histones


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0000266 abnormal cardiac morphology "anomalies in the hollow, muscular organ that maintains the circulation of the blood" [MeSH:National Library of Medicine - Medical Subject Headings , 2003]
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Allelic Composition: Kdm6aGt(RRA094)Byg/Kdm6aGt(RRA094)Byg
Genetic Background: either: (involves: 129 * CD-1) or (involves: 129P2/OlaHsd * CD-1) or (involves: 129P2/OlaHsd * C57BL/6 * CD-1)

 MP:0000280 thin ventricular wall "decreased depth of the cardiac wall of the heart ventricles" [J:45302]
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Allelic Composition: Kdm6aGt(RRA094)Byg/Y,X/UtyGt(XS0378)Wtsi
Genetic Background: either: (involves: 129 * CD-1) or (involves: 129P2/OlaHsd * CD-1) or (involves: 129P2/OlaHsd * C57BL/6 * CD-1)

 MP:0001787 pericardial edema "accumulation of watery fluid in the pericardial sac of the heart" [J:52597]
Show

Allelic Composition: Kdm6aGt(RRA094)Byg/Y,X/UtyGt(XS0378)Wtsi
Genetic Background: either: (involves: 129 * CD-1) or (involves: 129P2/OlaHsd * CD-1) or (involves: 129P2/OlaHsd * C57BL/6 * CD-1)

 MP:0002169 no phenotype detected "normal, viable and fertile appearance and behavior; indistinguishable from controls" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Kdm6atm1c(EUCOMM)Wtsi/Kdm6atm1c(EUCOMM)Wtsi,Edil3Tg(Sox2-cre)1Amc/Edil3+
Genetic Background: either: (involves: C57BL/6 * CBA * CD-1) or (involves: 129 * C57BL/6 * CBA * CD-1)

 MP:0002188 small heart "reduced size of the heart relative to average" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator, J:67044]
Show

Allelic Composition: Kdm6aGt(RRA094)Byg/Y,X/UtyGt(XS0378)Wtsi
Genetic Background: either: (involves: 129 * CD-1) or (involves: 129P2/OlaHsd * CD-1) or (involves: 129P2/OlaHsd * C57BL/6 * CD-1)

 MP:0004251 failure of looping morphogenesis "failure of the primitive heart tube to initiate or complete looping" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Kdm6aGt(RRA094)Byg/Y,X/UtyGt(XS0378)Wtsi
Genetic Background: either: (involves: 129 * CD-1) or (involves: 129P2/OlaHsd * CD-1) or (involves: 129P2/OlaHsd * C57BL/6 * CD-1)

 MP:0010503 myocardial trabeculae hypoplasia "underdevelopment or reduced size of the supporting bundles of muscular fibers lining the walls of the heart, usually due to a reduced number of cells" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Kdm6aGt(RRA094)Byg/Y,X/UtyGt(XS0378)Wtsi
Genetic Background: either: (involves: 129 * CD-1) or (involves: 129P2/OlaHsd * CD-1) or (involves: 129P2/OlaHsd * C57BL/6 * CD-1)

 MP:0010725 thin interventricular septum "decreased thickness of the wall between the two lower chambers of the heart" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Kdm6aGt(RRA094)Byg/Y,X/UtyGt(XS0378)Wtsi
Genetic Background: either: (involves: 129 * CD-1) or (involves: 129P2/OlaHsd * CD-1) or (involves: 129P2/OlaHsd * C57BL/6 * CD-1)

 MP:0011098 complete embryonic lethality during organogenesis "death of all organisms of a given genotype in a population between embryo turning and the completion of organogenesis (Mus: E9 to less than E14)" [MGI:csmith]
Show

Allelic Composition: Kdm6aGt(RRA094)Byg/Y,X/UtyGt(XS0378)Wtsi
Genetic Background: either: (involves: 129 * CD-1) or (involves: 129P2/OlaHsd * CD-1) or (involves: 129P2/OlaHsd * C57BL/6 * CD-1)

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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