ENSDARG00000061759


Danio rerio

Features
Gene ID: ENSDARG00000061759
  
Biological name :kdm6a
  
Synonyms : kdm6a / lysine (K)-specific demethylase 6A
  
Possible biological names infered from orthology : lysine demethylase 6A / Lysine-specific demethylase 6A / O14607 / O15550 / O70546 / ubiquitously transcribed tetratricopeptide repeat containing, Y-linked / ubiquitously transcribed tetratricopeptide repeat gene, Y chromosome / UTY
  
Species: Danio rerio
  
Chr. number: 9
Strand: 1
Band:
Gene start: 33788389
Gene end: 33862124
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000082902
Ensembl peptide - ENSDARP00000116325
NCBI entrez gene - 569277     See in Manteia.
swissprot - F1Q597
swissprot - F6PBE4
ZFIN ID - ZDB-GENE-081105-56
Ensembl - ENSDARG00000061759
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ENSGALG00000016217Gallus gallus
 KDM6AENSG00000147050Homo sapiens
 UTYENSG00000183878Homo sapiens
 Kdm6aENSMUSG00000037369Mus musculus
 UtyENSMUSG00000068457Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
kdm6al / lysine (K)-specific demethylase 6A, likeENSDARG0000005979463
kdm6ba / lysine (K)-specific demethylase 6B, a / KDM6B* / O15054* / Q5NCY0* / lysine demethylase 6B* / Lysine-specific demethylase 6B *ENSDARG0000008808730
kdm6bb / lysine (K)-specific demethylase 6B, bENSDARG0000005692930


Protein motifs (from Interpro)
Interpro ID Name
 IPR003347  JmjC domain
 IPR011990  Tetratricopeptide-like helical domain superfamily
 IPR013026  Tetratricopeptide repeat-containing domain
 IPR019734  Tetratricopeptide repeat
 IPR029516  Histone demethylase UTY


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007420 brain development IMP
 biological_processGO:0008354 germ cell migration IMP
 biological_processGO:0010468 regulation of gene expression IEA
 biological_processGO:0048703 embryonic viscerocranium morphogenesis IMP
 biological_processGO:0060026 convergent extension IMP
 biological_processGO:0060324 face development IMP
 biological_processGO:0071557 histone H3-K27 demethylation IEA
 molecular_functionGO:0046872 metal ion binding IEA
 molecular_functionGO:0071558 histone demethylase activity (H3-K27 specific) IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000008 brain brain decreased size , abnormal
Show

 ZFA:0000009 cardiac ventricle cardiac ventricle orientation atrium , abnormal
Show

 ZFA:0000029 hindbrain hindbrain decreased size , abnormal
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 ZFA:0000032 hypothalamus hypothalamus decreased thickness , abnormal
Show

 ZFA:0000054 pericardium pericardium edematous , abnormal
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 ZFA:0000109 forebrain forebrain nucleus elongated , abnormal
forebrain neuron differentiation decreased process quality , abnormal
Show

 ZFA:0000128 midbrain midbrain nucleus elongated , abnormal
midbrain neuron differentiation decreased process quality , abnormal
Show

 ZFA:0000135 notochord notochord increased width , abnormal
Show

 ZFA:0000160 tegmentum tegmentum decreased thickness , abnormal
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 ZFA:0000445 optic tectum optic tectum decreased thickness , abnormal
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 ZFA:0000545 medulla oblongata medulla oblongata decreased thickness , abnormal
Show

 ZFA:0001094 whole organism whole organism dead , abnormal
whole organism anterior-posterior axis shortened , abnormal
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 ZFA:0001114 head head lacks all parts of type cleithrum , abnormal
head lacks all parts of type opercle , abnormal
head lacks all parts of type Meckels cartilage , abnormal
head lacks all parts of type ceratohyal cartilage , abnormal
head lacks all parts of type pharyngeal arch 3-7 , abnormal
Show

 ZFA:0001205 Meckel s cartilage Meckels cartilage hypoplastic , abnormal
Meckels cartilage decreased distance ceratohyal cartilage , abnormal
Show

 ZFA:0001273 ventral mandibular arch ventral mandibular arch decreased size , abnormal
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 ZFA:0001399 palatoquadrate cartilage palatoquadrate cartilage hypoplastic , abnormal
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 ZFA:0001400 ceratohyal cartilage ceratohyal cartilage hypoplastic , abnormal
ceratohyal cartilage kinked , abnormal
Show

 ZFA:0001405 ethmoid cartilage ethmoid cartilage shortened , abnormal
Show

 ZFA:0001516 ceratobranchial cartilage ceratobranchial cartilage decreased size , abnormal
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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