ENSMUSG00000069631


Mus musculus

Features
Gene ID: ENSMUSG00000069631
  
Biological name :Strada
  
Synonyms : Q3UUJ4 / STE20-related kinase adapter protein alpha / Strada
  
Possible biological names infered from orthology : Q7RTN6 / STE20-related kinase adaptor alpha
  
Species: Mus musculus
  
Chr. number: 11
Strand: -1
Band: E1
Gene start: 106163330
Gene end: 106202168
  
Corresponding Affymetrix probe sets: 10392070 (MoGene1.0st)   1428188_at (Mouse Genome 430 2.0 Array)   1433185_at (Mouse Genome 430 2.0 Array)   1433186_at (Mouse Genome 430 2.0 Array)   1438591_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000115555
Ensembl peptide - ENSMUSP00000007444
Ensembl peptide - ENSMUSP00000099361
Ensembl peptide - ENSMUSP00000102480
NCBI entrez gene - 72149     See in Manteia.
MGI - MGI:1919399
RefSeq - XM_011249270
RefSeq - NM_028126
RefSeq - XM_006534293
RefSeq - XM_006534294
RefSeq - XM_006534295
RefSeq - XM_006534296
RefSeq - XM_006534297
RefSeq - NM_001252448
RefSeq - NM_001252449
RefSeq Peptide - NP_082402
RefSeq Peptide - NP_001239377
RefSeq Peptide - NP_001239378
swissprot - B1AR92
swissprot - Q3UUJ4
swissprot - B1AR89
Ensembl - ENSMUSG00000069631
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 stradaENSDARG00000037929Danio rerio
 Q5ZK47ENSGALG00000000550Gallus gallus
 Q7RTN6ENSG00000266173Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q8K4T3 / Stradb / STE20-related kinase adapter protein beta / Q9C0K7* / STE20-related kinase adaptor beta*ENSMUSG0000002602742
Oxsr1 / Q6P9R2 / Serine/threonine-protein kinase OSR1 / O95747* / oxidative stress responsive 1*ENSMUSG0000003673726
Stk39 / Q9Z1W9 / STE20/SPS1-related proline-alanine-rich protein kinase / Q9UEW8* / serine/threonine kinase 39*ENSMUSG0000002703026


Protein motifs (from Interpro)
Interpro ID Name
 IPR000719  Protein kinase domain
 IPR011009  Protein kinase-like domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006468 protein phosphorylation IEA
 biological_processGO:0006611 protein export from nucleus ISS
 biological_processGO:0007049 cell cycle IEA
 biological_processGO:0007346 regulation of mitotic cell cycle IBA
 biological_processGO:0023014 signal transduction by protein phosphorylation IBA
 biological_processGO:0031098 stress-activated protein kinase signaling cascade IBA
 biological_processGO:0032147 activation of protein kinase activity ISO
 biological_processGO:0042981 regulation of apoptotic process IBA
 biological_processGO:0071902 positive regulation of protein serine/threonine kinase activity IEA
 cellular_componentGO:0005634 nucleus ISO
 cellular_componentGO:0005654 nucleoplasm ISO
 cellular_componentGO:0005737 cytoplasm IBA
 cellular_componentGO:0005829 cytosol ISO
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0004672 protein kinase activity IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0019900 kinase binding ISO
 molecular_functionGO:0030295 protein kinase activator activity ISO
 molecular_functionGO:0043539 protein serine/threonine kinase activator activity ISO


Pathways (from Reactome)
Pathway description
Energy dependent regulation of mTOR by LKB1-AMPK


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSMUSG00000003068 Stk11 / Q9WTK7 / Serine/threonine-protein kinase STK11 / Q15831* / serine/threonine kinase 11*  / complex / reaction
 ENSMUSG00000036707 Cab39 / Q06138 / Mus musculus calcium binding protein 39 (Cab39), transcript variant 3, mRNA. / Q9Y376* / calcium binding protein 39*  / complex / reaction
 ENSMUSG00000021981 Cab39l / Q9DB16 / Calcium-binding protein 39-like / Q9H9S4*  / complex / reaction






 

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