ENSMUSG00000069806


Mus musculus

Features
Gene ID: ENSMUSG00000069806
  
Biological name :Cacng7
  
Synonyms : Cacng7 / P62956 / Voltage-dependent calcium channel gamma-7 subunit
  
Possible biological names infered from orthology : calcium voltage-gated channel auxiliary subunit gamma 7 / P62955
  
Species: Mus musculus
  
Chr. number: 7
Strand: 1
Band: A1
Gene start: 3332955
Gene end: 3368221
  
Corresponding Affymetrix probe sets: 10569714 (MoGene1.0st)   1426336_at (Mouse Genome 430 2.0 Array)   1439745_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000090567
NCBI entrez gene - 81904     See in Manteia.
MGI - MGI:1932374
RefSeq - XM_006540441
RefSeq - NM_133189
RefSeq Peptide - NP_573452
swissprot - P62956
swissprot - B9EJ14
Ensembl - ENSMUSG00000069806
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 cacng7aENSDARG00000063006Danio rerio
 cacng7bENSDARG00000070624Danio rerio
 CACNG7ENSG00000105605Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Cacng5 / Q8VHW4 / Voltage-dependent calcium channel gamma-5 subunit / Q9UF02* / calcium voltage-gated channel auxiliary subunit gamma 5*ENSMUSG0000004037372
Cacng2 / O88602 / Voltage-dependent calcium channel gamma-2 subunit / Q9Y698* / calcium voltage-gated channel auxiliary subunit gamma 2*ENSMUSG0000001914630
Cacng8 / voltage-dependent calcium channel gamma-8 subunit / Q8WXS5* / calcium voltage-gated channel auxiliary subunit gamma 8*ENSMUSG0000005339530
Cacng3 / Q9JJV5 / Voltage-dependent calcium channel gamma-3 subunit / O60359* / calcium voltage-gated channel auxiliary subunit gamma 3*ENSMUSG0000006618929
Cacng4 / Q9JJV4 / Voltage-dependent calcium channel gamma-4 subunit / Q9UBN1* / calcium voltage-gated channel auxiliary subunit gamma 4*ENSMUSG0000002072328


Protein motifs (from Interpro)
Interpro ID Name
 IPR004031  PMP-22/EMP/MP20/Claudin superfamily
 IPR008368  Voltage-dependent calcium channel, gamma subunit
 IPR008371  Voltage-dependent calcium channel, gamma-7 subunit


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006811 ion transport IEA
 biological_processGO:0006816 calcium ion transport IEA
 biological_processGO:0019226 transmission of nerve impulse IBA
 biological_processGO:0034765 regulation of ion transmembrane transport IEA
 biological_processGO:0070588 calcium ion transmembrane transport IBA
 biological_processGO:2000311 regulation of AMPA receptor activity IBA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0032281 AMPA glutamate receptor complex ISS
 molecular_functionGO:0005244 voltage-gated ion channel activity IEA
 molecular_functionGO:0005245 voltage-gated calcium channel activity IBA
 molecular_functionGO:0005262 calcium channel activity IEA
 molecular_functionGO:0016247 channel regulator activity IBA


Pathways (from Reactome)
Pathway description
Phase 0 - rapid depolarisation
Phase 2 - plateau phase


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0001262 decreased body weight "lower than normal average weight " [J:61295]
Show

Allelic Composition: Cacng2tm1Mwa/Cacng2tm1Mwa,Cacng7tm1Mwa/Cacng7tm1Mwa
Genetic Background: involves: C57BL/6 * C57BL/6N * CBA

 MP:0001393 ataxia "inability to coordinate voluntary muscular movements" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:67231]
Show

Allelic Composition: Cacng2tm1Mwa/Cacng2tm1Mwa,Cacng7tm1Mwa/Cacng7tm1Mwa
Genetic Background: involves: C57BL/6 * C57BL/6N * CBA

 MP:0001406 abnormal gait "unusual or distinctive way of walking" [J:65038]
Show

Allelic Composition: Cacng2tm1Mwa/Cacng2tm1Mwa,Cacng7tm1Mwa/Cacng7tm1Mwa
Genetic Background: involves: C57BL/6 * C57BL/6N * CBA

 MP:0002169 no phenotype detected "normal, viable and fertile appearance and behavior; indistinguishable from controls" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Cacng2tm1Mwa/Cacng2tm1Mwa
Genetic Background: involves: C57BL/6 * C57BL/6N * CBA

 MP:0002910 abnormal excitatory postsynaptic currents "defect in the size or duration of currents detected in postsynaptic cells when an excitatory impulse arrives at the synapse causing depolarization" [Principles of Neural Science , 3rd edition:ISBN 0-8385-8034-3]
Show

Allelic Composition: Cacng2tm1Mwa/Cacng2tm1Mwa,Cacng7tm1Mwa/Cacng7tm1Mwa
Genetic Background: involves: C57BL/6 * C57BL/6N * CBA

 MP:0003312 abnormal locomotor coordination "reduced ability of an animal to maintain skillful and effective interaction of movements while engaging in locomotor activity" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Cacng2tm1Mwa/Cacng2tm1Mwa,Cacng7tm1Mwa/Cacng7tm1Mwa
Genetic Background: involves: C57BL/6 * C57BL/6N * CBA

 MP:0011003 reduced AMPA-mediated synaptic currents "reduction in the measured amplitude, current density or duration of response to stimulation of AMPA receptors" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Cacng2tm1Mwa/Cacng2tm1Mwa,Cacng7tm1Mwa/Cacng7tm1Mwa
Genetic Background: involves: C57BL/6 * C57BL/6N * CBA

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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