Manteia

ENSMUSG00000070520

Mus musculus

Features

Gene ID:	ENSMUSG00000070520

Biological name :	Nsmce3

Synonyms :	Non-structural maintenance of chromosomes element 3 homolog / Nsmce3 / Q9CPR8

Possible biological names infered from orthology :	NSE3 homolog, SMC5-SMC6 complex component / Q96MG7

Species:	Mus musculus

Chr. number:	7
Strand:	-1
Band:	C
Gene start:	64867052
Gene end:	64872997

Corresponding Affymetrix probe sets:	10564337 (MoGene1.0st) 1422554_at (Mouse Genome 430 2.0 Array)

Cross references:	Ensembl peptide - ENSMUSP00000091889 NCBI entrez gene - 66647 See in Manteia. MGI - MGI:1913897 RefSeq - NM_023239 RefSeq Peptide - NP_075728 swissprot - Q9CPR8 Ensembl - ENSMUSG00000070520

See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed

Ortholog prediction (from Ensembl)

Ortholog name	ID	Species
ndnl2	ENSDARG00000058212	Danio rerio
NSMCE3	ENSG00000185115	Homo sapiens

Paralog prediction (from Ensembl)

Paralog name	ID	Similarity(%)
1700020D05Rik / RIKEN cDNA 1700020D05 gene / NSMCE3* / Q96MG7* / NSE3 homolog, SMC5-SMC6 complex component*	ENSMUSG00000100937	68
Magee1 / Q6PCZ4 / Melanoma-associated antigen E1 / Q9HCI5* / MAGE family member E1*	ENSMUSG00000031227	40
Maged2 / Mus musculus melanoma antigen, family D, 2 (Maged2), transcript variant 4, mRNA. / Q9UNF1* / MAGE family member D2*	ENSMUSG00000025268	38
Q8BQR7 / Mageb18 / Melanoma-associated antigen B18 / Q96M61* / MAGE family member B18*	ENSMUSG00000067649	38
Tro / trophinin / Q12816*	ENSMUSG00000025272	38
Mageb1 / Q8N7X4* / MAGEB6* / MAGEB6B* / MAGE family member B6* / MAGE family member B6B*	ENSMUSG00000062162	37
Mageb3 / Q8N7X4* / MAGEB6* / MAGEB6B* / MAGE family member B6* / MAGE family member B6B*	ENSMUSG00000074881	37
Mageb2 / Q8N7X4* / MAGEB6* / MAGEB6B* / MAGE family member B6* / MAGE family member B6B*	ENSMUSG00000073069	37
Maged1 / Q9QYH6 / Melanoma-associated antigen D1 / Q9Y5V3* / MAGE family member D1*	ENSMUSG00000025151	35
Magel2 / Q9QZ04 / MAGE-like protein 2 / Q9UJ55* / MAGE family member L2*	ENSMUSG00000056972	34
Gm44	ENSMUSG00000091497	34
Q9CWV4 / Mageb16 / Melanoma-associated antigen B16 / A2A368* / MAGE family member B16*	ENSMUSG00000046942	34
Magea10 / P43363* / MAGE family member A10*	ENSMUSG00000043453	34
Gm5072 / Q8N7X4* / MAGEB6* / MAGEB6B* / MAGE family member B6* / MAGE family member B6B*	ENSMUSG00000094861	33
Mageb4 / A2A9R3 / Melanoma-associated antigen B4 / P43366* / MAGEB1* / MAGEB2* / O15479* / O15481* / MAGE family member B1* / MAGE family member B4* / MAGE family member B2*	ENSMUSG00000035427	33
Magea5 / P43363* / MAGEA10* / MAGE family member A10*	ENSMUSG00000079349	33
4930550L24Rik / RIKEN cDNA 4930550L24 gene / MAGEC2* / MAGEC3* / Q8TD91* / Q9UBF1* / MAGEC1* / O60732* / MAGE family member C1* / MAGE family member C2* / MAGE family member C3*	ENSMUSG00000046180	33
Gm8914 / Q8N7X4* / MAGEB6* / MAGEB6B* / MAGE family member B6* / MAGE family member B6B*	ENSMUSG00000096072	33
1700080O16Rik / RIKEN cDNA 1700080O16 gene / P43363* / MAGEA10* / MAGE family member A10*	ENSMUSG00000031118	32
Ndn / P25233 / Necdin / Q99608* / necdin, MAGE family member*	ENSMUSG00000033585	32

Protein motifs (from Interpro)

Interpro ID	Name
IPR002190	MAGE homology domain
IPR037445	Melanoma-associated antigen

Gene Ontology (GO)

Type	GO ID	Term	Ev.Code
biological_process	GO:0006281	DNA repair	ISO
biological_process	GO:0006310	DNA recombination	IEA
biological_process	GO:0006355	regulation of transcription, DNA-templated	IDA
biological_process	GO:0006974	cellular response to DNA damage stimulus	IEA
biological_process	GO:0031398	positive regulation of protein ubiquitination	ISO
biological_process	GO:0034644	cellular response to UV	ISO
biological_process	GO:0040008	regulation of growth	IEA
biological_process	GO:0071478	cellular response to radiation	ISS
biological_process	GO:0072711	cellular response to hydroxyurea	ISO
cellular_component	GO:0000781	chromosome, telomeric region	IEA
cellular_component	GO:0005634	nucleus	IEA
cellular_component	GO:0005694	chromosome	IEA
cellular_component	GO:0005737	cytoplasm	IEA
cellular_component	GO:0030915	Smc5-Smc6 complex	ISS
molecular_function	GO:0005515	protein binding	IPI
molecular_function	GO:0046983	protein dimerization activity	ISO

Pathways (from Reactome)

Pathway description

SUMOylation of DNA damage response and repair proteins

Phenotype (from MGI, Zfin or HPO)

Phenotype

Definition

Genetic BG

No match

Interacting proteins (from Reactome)

Interactor ID

Name

Interaction type

No match

0 s.

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		© Olivier Tassy / Olivier Pourquie 2007-2024 contact: otassy@igbmc.fr