ENSMUSG00000070719


Mus musculus

Features
Gene ID: ENSMUSG00000070719
  
Biological name :Pla2g4d
  
Synonyms : Cytosolic phospholipase A2 delta / Pla2g4d / Q50L43
  
Possible biological names infered from orthology : phospholipase A2 group IVD / Q86XP0
  
Species: Mus musculus
  
Chr. number: 2
Strand: -1
Band: E5
Gene start: 120265595
Gene end: 120289197
  
Corresponding Affymetrix probe sets: 10486425 (MoGene1.0st)   1453405_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000092252
NCBI entrez gene - 78390     See in Manteia.
MGI - MGI:1925640
RefSeq - XM_011239849
RefSeq - NM_001024137
RefSeq - XM_006500413
RefSeq Peptide - NP_001019308
swissprot - Q50L43
Ensembl - ENSMUSG00000070719
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ENSGALG00000008727Gallus gallus
 Q86XP0ENSG00000159337Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Gm28042 / P0C869* / PLA2G4B* / JMJD7-PLA2G4B* / JMJD7-PLA2G4B readthrough* / phospholipase A2 group IVB*ENSMUSG0000003385246
Pla2g4b / P0C869* / JMJD7-PLA2G4B* / JMJD7-PLA2G4B readthrough* / phospholipase A2 group IVB*ENSMUSG0000009848845
Q50L42 / Pla2g4e / Cytosolic phospholipase A2 epsilon / Q3MJ16* / phospholipase A2 group IVE*ENSMUSG0000005021141
Q50L41 / Pla2g4f / Cytosolic phospholipase A2 zeta / Q68DD2* / phospholipase A2 group IVF*ENSMUSG0000004697139
P47713 / Pla2g4a / phospholipase A2, group IVA (cytosolic, calcium-dependent) / P47712* / phospholipase A2 group IVA*ENSMUSG0000005622026
Q64GA5 / Pla2g4c / Cytosolic phospholipase A2 gamma / Q9UP65* / phospholipase A2 group IVC*ENSMUSG0000003384715


Protein motifs (from Interpro)
Interpro ID Name
 IPR000008  C2 domain
 IPR002642  Lysophospholipase, catalytic domain
 IPR016035  Acyl transferase/acyl hydrolase/lysophospholipase
 IPR035892  C2 domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006629 lipid metabolic process IEA
 biological_processGO:0008152 metabolic process IEA
 biological_processGO:0009395 phospholipid catabolic process IEA
 biological_processGO:0016042 lipid catabolic process IEA
 biological_processGO:0046475 glycerophospholipid catabolic process IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005829 cytosol IEA
 cellular_componentGO:0016020 membrane IEA
 molecular_functionGO:0004620 phospholipase activity IEA
 molecular_functionGO:0004623 phospholipase A2 activity IDA
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0046872 metal ion binding IEA
 molecular_functionGO:0047498 calcium-dependent phospholipase A2 activity IEA
 molecular_functionGO:0102567 phospholipase A2 activity (consuming 1,2-dipalmitoylphosphatidylcholine) IEA
 molecular_functionGO:0102568 phospholipase A2 activity consuming 1,2-dioleoylphosphatidylethanolamine) IEA


Pathways (from Reactome)
Pathway description
Acyl chain remodelling of PC
Acyl chain remodelling of PS
Acyl chain remodelling of PE
Acyl chain remodelling of PI
Acyl chain remodelling of PG
Hydrolysis of LPC
Synthesis of PA


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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