ENSMUSG00000050211


Mus musculus

Features
Gene ID: ENSMUSG00000050211
  
Biological name :Pla2g4e
  
Synonyms : Cytosolic phospholipase A2 epsilon / Pla2g4e / Q50L42
  
Possible biological names infered from orthology : phospholipase A2 group IVE / Q3MJ16
  
Species: Mus musculus
  
Chr. number: 2
Strand: -1
Band: E5
Gene start: 120166412
Gene end: 120245335
  
Corresponding Affymetrix probe sets: 10486403 (MoGene1.0st)   1429862_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000087525
NCBI entrez gene - 329502     See in Manteia.
MGI - MGI:1919144
RefSeq - XM_006499773
RefSeq - NM_177845
RefSeq - XM_006499771
RefSeq - XM_006499772
RefSeq - XM_006499770
RefSeq Peptide - NP_808513
swissprot - Q50L42
Ensembl - ENSMUSG00000050211
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ENSGALG00000028402Gallus gallus
 ENSGALG00000029454Gallus gallus
 ENSGALG00000026584Gallus gallus
 ENSGALG00000045796Gallus gallus
 ENSGALG00000044307Gallus gallus
 ENSGALG00000043401Gallus gallus
 ENSGALG00000020458Gallus gallus
 Q3MJ16ENSG00000188089Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q50L43 / Pla2g4d / Cytosolic phospholipase A2 delta / Q86XP0* / phospholipase A2 group IVD*ENSMUSG0000007071939
Gm28042 / P0C869* / PLA2G4B* / JMJD7-PLA2G4B* / JMJD7-PLA2G4B readthrough* / phospholipase A2 group IVB*ENSMUSG0000003385238
Pla2g4b / P0C869* / JMJD7-PLA2G4B* / JMJD7-PLA2G4B readthrough* / phospholipase A2 group IVB*ENSMUSG0000009848837
Q50L41 / Pla2g4f / Cytosolic phospholipase A2 zeta / Q68DD2* / phospholipase A2 group IVF*ENSMUSG0000004697134
P47713 / Pla2g4a / phospholipase A2, group IVA (cytosolic, calcium-dependent) / P47712* / phospholipase A2 group IVA*ENSMUSG0000005622025
Q64GA5 / Pla2g4c / Cytosolic phospholipase A2 gamma / Q9UP65* / phospholipase A2 group IVC*ENSMUSG0000003384714


Protein motifs (from Interpro)
Interpro ID Name
 IPR000008  C2 domain
 IPR002642  Lysophospholipase, catalytic domain
 IPR016035  Acyl transferase/acyl hydrolase/lysophospholipase
 IPR035892  C2 domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006629 lipid metabolic process IEA
 biological_processGO:0008152 metabolic process IEA
 biological_processGO:0009395 phospholipid catabolic process IEA
 biological_processGO:0016042 lipid catabolic process IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005764 lysosome IEA
 cellular_componentGO:0005765 lysosomal membrane IEA
 cellular_componentGO:0005829 cytosol IEA
 cellular_componentGO:0016020 membrane IEA
 molecular_functionGO:0004620 phospholipase activity IEA
 molecular_functionGO:0004623 phospholipase A2 activity IDA
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0046872 metal ion binding IEA
 molecular_functionGO:0102567 phospholipase A2 activity (consuming 1,2-dipalmitoylphosphatidylcholine) IEA
 molecular_functionGO:0102568 phospholipase A2 activity consuming 1,2-dioleoylphosphatidylethanolamine) IEA


Pathways (from Reactome)
Pathway description
Acyl chain remodelling of PC
Acyl chain remodelling of PS
Acyl chain remodelling of PE
Acyl chain remodelling of PI
Hydrolysis of LPC


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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