ENSMUSG00000071856


Mus musculus

Features
Gene ID: ENSMUSG00000071856
  
Biological name :Mcc
  
Synonyms : Mcc / mutated in colorectal cancers
  
Possible biological names infered from orthology : P23508
  
Species: Mus musculus
  
Chr. number: 18
Strand: -1
Band: B3
Gene start: 44425060
Gene end: 44812182
  
Corresponding Affymetrix probe sets: 10458731 (MoGene1.0st)   1438081_at (Mouse Genome 430 2.0 Array)   1442741_at (Mouse Genome 430 2.0 Array)   1442892_at (Mouse Genome 430 2.0 Array)   1459524_at (Mouse Genome 430 2.0 Array)   1459752_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000087318
Ensembl peptide - ENSMUSP00000128032
NCBI entrez gene - 328949     See in Manteia.
MGI - MGI:96930
RefSeq - XM_006526026
RefSeq - NM_001085374
RefSeq - XM_006526023
RefSeq - XM_006526024
RefSeq - XM_006526025
RefSeq - NM_001085373
RefSeq Peptide - NP_001078843
RefSeq Peptide - NP_001078842
swissprot - G3UW40
swissprot - E9PWI3
Ensembl - ENSMUSG00000071856
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 mccENSDARG00000105237Danio rerio
 MCCENSGALG00000000208Gallus gallus
 MCCENSG00000171444Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q8R370 / Ushbp1 / USH1 protein network component harmonin binding protein 1 / Q8N6Y0*ENSMUSG0000003491117


Protein motifs (from Interpro)
Interpro ID Name
 IPR002048  EF-hand domain
 IPR011992  EF-hand domain pair
 IPR018247  EF-Hand 1, calcium-binding site
 IPR019536  Usher syndrome type-1C protein-binding protein 1, PDZ domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0010633 negative regulation of epithelial cell migration ISO
 biological_processGO:0045184 establishment of protein localization ISO
 biological_processGO:0050680 negative regulation of epithelial cell proliferation ISO
 biological_processGO:0090090 negative regulation of canonical Wnt signaling pathway ISO
 cellular_componentGO:0005634 nucleus ISO
 cellular_componentGO:0005654 nucleoplasm ISO
 cellular_componentGO:0005737 cytoplasm ISO
 cellular_componentGO:0005829 cytosol ISO
 cellular_componentGO:0005886 plasma membrane ISO
 molecular_functionGO:0005509 calcium ion binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0002169 no phenotype detected "normal, viable and fertile appearance and behavior; indistinguishable from controls" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Itgb1tm1Ref/Itgb1tm12.1Ref,Tg(KRT5-cre)5132Jlj/0
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6J * DBA/2J

Allelic Composition: MccGt(W197F04)Wrst/MccGt(W197F04)Wrst
Genetic Background: involves: 129S2/SvPas * C57BL/6

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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