ENSMUSG00000072845


Mus musculus

Features
Gene ID: ENSMUSG00000072845
  
Biological name :Tmprss11a
  
Synonyms : Q3UQ41 / Tmprss11a / Transmembrane protease serine 11A
  
Possible biological names infered from orthology : Q6ZMR5 / transmembrane serine protease 11A
  
Species: Mus musculus
  
Chr. number: 5
Strand: -1
Band: E1
Gene start: 86410410
Gene end: 86468990
  
Corresponding Affymetrix probe sets: 10530974 (MoGene1.0st)   1455848_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000098634
NCBI entrez gene - 194597     See in Manteia.
MGI - MGI:2684853
RefSeq - NM_001033233
RefSeq - XM_006534840
RefSeq Peptide - NP_001028405
swissprot - Q3UQ41
Ensembl - ENSMUSG00000072845
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ENSGALG00000011792Gallus gallus
 Q6ZMR5ENSG00000187054Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q8BZ10 / Tmprss11g / transmembrane protease, serine 11gENSMUSG0000007945144
Q8BHM9 / Tmprss11f / Transmembrane protease serine 11F / Q6ZWK6* / transmembrane serine protease 11F*ENSMUSG0000004876444
Q1JRP2 / Tmprss11c / transmembrane protease, serine 11cENSMUSG0000006118442
Q5S248 / Tmprss11e / Transmembrane protease serine 11E Transmembrane protease serine 11E non-catalytic chain Transmembrane protease serine 11E catalytic chain / Q9UL52* / transmembrane seri...ENSMUSG0000005453739
Q14C59 / Tmprss11b / Transmembrane protease serine 11B-like protein / Q86T26* / transmembrane serine protease 11B*ENSMUSG0000003586139
Q8VHK8 / Tmprss11d / Transmembrane protease serine 11D Transmembrane protease serine 11D non-catalytic chain Transmembrane protease serine 11D catalytic chain / O60235* / transmembrane seri...ENSMUSG0000006125938
Acr / P23578 / Acrosin Acrosin light chain Acrosin heavy chain / P10323* / acrosin*ENSMUSG0000002262229
F2YMG0 / Prss56 / Serine protease 56 / P0CW18*ENSMUSG0000003648028
Cfi / Q61129 / Mus musculus complement component factor i (Cfi), transcript variant 2, mRNA. / P05156* / AC126283.2* / complement factor I*ENSMUSG0000005895227
Q3V0Q7 / Tmprss12 / Transmembrane protease serine 12 / Q86WS5* / transmembrane serine protease 12*ENSMUSG0000004563124


Protein motifs (from Interpro)
Interpro ID Name
 IPR000082  SEA domain
 IPR001254  Serine proteases, trypsin domain
 IPR001314  Peptidase S1A, chymotrypsin family
 IPR009003  Peptidase S1, PA clan
 IPR017329  Peptidase S1A, HAT/DESC1
 IPR018114  Serine proteases, trypsin family, histidine active site
 IPR033116  Serine proteases, trypsin family, serine active site
 IPR036364  SEA domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006508 proteolysis IEA
 biological_processGO:0007049 cell cycle IEA
 cellular_componentGO:0005576 extracellular region IEA
 cellular_componentGO:0005887 integral component of plasma membrane IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0004252 serine-type endopeptidase activity IEA
 molecular_functionGO:0008233 peptidase activity IEA
 molecular_functionGO:0008236 serine-type peptidase activity IEA
 molecular_functionGO:0016787 hydrolase activity IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0000659 prostate gland hyperplasia "increased cell number in the prostate" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:63764]
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Allelic Composition: Gbe1tm1.1Hoa/Gbe1tm1.1Hoa
Genetic Background: involves: 129S7/SvEvBrd

 MP:0002169 no phenotype detected "normal, viable and fertile appearance and behavior; indistinguishable from controls" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Celsr2tm1Dgen/Celsr2+
Genetic Background: involves: 129P2/OlaHsd * C57BL/6

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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