ENSMUSG00000075031


Mus musculus

Features
Gene ID: ENSMUSG00000075031
  
Biological name :Hist1h2bb
  
Synonyms : Hist1h2bb / Histone H2B type 1-B / Q64475
  
Possible biological names infered from orthology : HIST1H2BM / histone cluster 1 H2B family member m / Q99879
  
Species: Mus musculus
  
Chr. number: 13
Strand: 1
Band: A3.1
Gene start: 23746734
Gene end: 23747241
  
Corresponding Affymetrix probe sets: 10403978 (MoGene1.0st)   10404061 (MoGene1.0st)   
  
Cross references: Ensembl peptide - ENSMUSP00000097294
NCBI entrez gene - 319178     See in Manteia.
MGI - MGI:2448377
RefSeq - NM_175664
RefSeq Peptide - NP_783595
swissprot - Q64475
Ensembl - ENSMUSG00000075031
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 CR354435.2ENSDARG00000109737Danio rerio
 CU302436.1ENSDARG00000111964Danio rerio
 CU302436.4ENSDARG00000114195Danio rerio
 FP236812.3ENSDARG00000114180Danio rerio
 FP340257.2ENSDARG00000113763Danio rerio
 hist1h2baENSDARG00000109370Danio rerio
 Q5BJA5ENSDARG00000104501Danio rerio
 Q5BJA5ENSDARG00000070297Danio rerio
 Q5BJA5ENSDARG00000075482Danio rerio
 si:ch211-113a14.11ENSDARG00000086591Danio rerio
 si:ch211-113a14.22ENSDARG00000105397Danio rerio
 si:ch211-113a14.22ENSDARG00000070289Danio rerio
 si:ch211-113a14.22ENSDARG00000114895Danio rerio
 si:dkey-108k21.11ENSDARG00000112561Danio rerio
 si:dkey-23a13.22ENSDARG00000105384Danio rerio
 si:dkey-261m9.19ENSDARG00000114125Danio rerio
 si:dkey-261m9.6ENSDARG00000116654Danio rerio
 zgc:112234ENSDARG00000105393Danio rerio
 zgc:112234ENSDARG00000105483Danio rerio
 zgc:112234ENSDARG00000105340Danio rerio
 zgc:112234ENSDARG00000105414Danio rerio
 zgc:112234ENSDARG00000111934Danio rerio
 zgc:112234ENSDARG00000104588Danio rerio
 zgc:112234ENSDARG00000102806Danio rerio
 zgc:112234ENSDARG00000099514Danio rerio
 zgc:112234ENSDARG00000105468Danio rerio
 zgc:112234ENSDARG00000078941Danio rerio
 zgc:112234ENSDARG00000105507Danio rerio
 zgc:114046ENSDARG00000091728Danio rerio
 zgc:171759ENSDARG00000100259Danio rerio
 zgc:171759ENSDARG00000115938Danio rerio
 zgc:173585ENSDARG00000089039Danio rerio
 zgc:194989ENSDARG00000114405Danio rerio
 Q99879ENSG00000273703Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
P10853 / Hist1h2bj / Histone H2B type 1-F/J/L ENSMUSG0000006930098
P10853 / Hist1h2bn / Histone H2B type 1-F/J/L ENSMUSG0000009521798
P10853 / Hist1h2bf / Histone H2B type 1-F/J/L ENSMUSG0000006926898
P10853 / Hist1h2bl / Histone H2B type 1-F/J/L ENSMUSG0000009433898
Q6ZWY9 / Hist1h2bg / Histone H2B type 1-C/E/G ENSMUSG0000005838597
P10854 / Hist1h2bm / Histone H2B type 1-M / P58876* / HIST1H2BD* / histone cluster 1 H2B family member d*ENSMUSG0000011427997
Q6ZWY9 / Hist1h2bc / Histone H2B type 1-C/E/G ENSMUSG0000001810297
Q8CGP1 / Hist1h2bk / Histone H2B type 1-K / H2BFS* / O60814* / P57053* / H2B histone family member S* / histone cluster 1 H2B family member k*ENSMUSG0000006272797
P10853 / Hist1h2bq / Histone H2B type 1-F/J/L ENSMUSG0000006930797
Q6ZWY9 / Hist1h2be / Histone H2B type 1-C/E/G / P62807* / HIST1H2BC* / histone cluster 1 H2B family member c*ENSMUSG0000004724697
Q64478 / Hist1h2bh / Histone H2B type 1-H ENSMUSG0000011445697
Q8CGP2 / Hist1h2bp / Histone H2B type 1-P ENSMUSG0000006930897
P10853 / Hist1h2br / Histone H2B type 1-F/J/L ENSMUSG0000006930397
Q9D2U9 / Hist3h2ba / Histone H2B type 3-A ENSMUSG0000005689595
Q64525 / Hist2h2bb / Histone H2B type 2-B / Q5QNW6* / HIST2H2BF* / histone cluster 2 H2B family member f*ENSMUSG0000010582795
Q64524 / Hist2h2be / Histone H2B type 2-E / P06899* / HIST1H2BJ* / histone cluster 1 H2B family member j*ENSMUSG0000006885494
P70696 / Hist1h2ba / Histone H2B type 1-A / Q96A08* / histone cluster 1 H2B family member a*ENSMUSG0000005079987
H2bfm / P0C1H6* / H2BFWT* / Q7Z2G1* / H2B histone family member M* / H2B histone family member W, testis specific*ENSMUSG0000004815552
Q9D9Z7 / 1700024P04Rik / RIKEN cDNA 1700024P04 geneENSMUSG0000004502241


Protein motifs (from Interpro)
Interpro ID Name
 IPR000558  Histone H2B
 IPR007125  Histone H2A/H2B/H3
 IPR009072  Histone-fold


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006334 nucleosome assembly IBA
 cellular_componentGO:0000786 nucleosome IEA
 cellular_componentGO:0005634 nucleus ISO
 cellular_componentGO:0005654 nucleoplasm TAS
 cellular_componentGO:0005694 chromosome IEA
 cellular_componentGO:0005829 cytosol ISO
 molecular_functionGO:0003677 DNA binding IBA
 molecular_functionGO:0046982 protein heterodimerization activity IEA


Pathways (from Reactome)
Pathway description
Packaging Of Telomere Ends
Formation of the beta-catenin:TCF transactivating complex
PRC2 methylates histones and DNA
Condensation of Prophase Chromosomes
Oxidative Stress Induced Senescence
Senescence-Associated Secretory Phenotype (SASP)
DNA Damage/Telomere Stress Induced Senescence
HDACs deacetylate histones
HATs acetylate histones
SIRT1 negatively regulates rRNA expression
NoRC negatively regulates rRNA expression
B-WICH complex positively regulates rRNA expression
Transcriptional regulation by small RNAs
Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3
Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks
Nonhomologous End-Joining (NHEJ)
Deposition of new CENPA-containing nucleosomes at the centromere
G2/M DNA damage checkpoint
RNA Polymerase I Promoter Opening
RNA Polymerase I Chain Elongation
E3 ubiquitin ligases ubiquitinate target proteins
RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function
Estrogen-dependent gene expression


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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