ENSDARG00000086591


Danio rerio

Features
Gene ID: ENSDARG00000086591
  
Biological name :si:ch211-113a14.11
  
Synonyms : si:ch211-113a14.11
  
Possible biological names infered from orthology : 1700024P04Rik / H2BFM / H2BFS / H2BFWT / H2B histone family member M / H2B histone family member S / H2B histone family member W, testis specific / HIST1H2BB / HIST1H2BC / HIST1H2BD / HIST1H2BE / HIST1H2BF / HIST1H2BG / HIST1H2BH / HIST1H2BI / HIST1H2BJ / HIST1H2BK / HIST1H2BL / HIST1H2BM / HIST1H2BN / HIST1H2BO / Hist1h2bp / Hist1h2bq / Hist1h2br / Hist2h2bb / HIST2H2BE / HIST2H2BF / Hist3h2ba / HIST3H2BB / histone cluster 1 H2B family member b / histone cluster 1 H2B family member c / histone cluster 1 H2B family member d / histone cluster 1 H2B family member e / histone cluster 1 H2B family member f / histone cluster 1 H2B family member g / histone cluster 1 H2B family member h / histone cluster 1 H2B family member i / histone cluster 1 H2B family member j / histone cluster 1 H2B family member k / histone cluster 1 H2B family member l / histone cluster 1 H2B family member m / histone cluster 1 H2B family member n / histone cluster 1 H2B family member o / histone cluster 2 H2B family member e / histone cluster 2 H2B family member f / histone cluster 3 H2B family member b / Histone H2B type 1-B / Histone H2B type 1-C/E/G / Histone H2B type 1-F/J/L / Histone H2B type 1-H / Histone H2B type 1-K / Histone H2B type 1-M / Histone H2B type 1-P / Histone H2B type 2-B / Histone H2B type 2-E / Histone H2B type 3-A / O60814 / P06899 / P0C1H6 / P10853 / P10854 / P23527 / P33778 / P57053 / P58876 / P62807 / Q16778 / Q5QNW6 / Q64475 / Q64478 / Q64524 / Q64525 / Q6ZWY9 / Q7Z2G1 / Q8CGP1 / Q8CGP2 / Q8N257 / Q93079 / Q99877 / Q99879 / Q99880 / Q9D2U9 / Q9D9Z7 / RIKEN cDNA 1700024P04 gene
  
Species: Danio rerio
  
Chr. number: 25
Strand: 1
Band:
Gene start: 36316280
Gene end: 36322775
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000126712
swissprot - R4GE02
ZFIN ID - ZDB-GENE-121214-162
Ensembl - ENSDARG00000086591
  
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 H2BFMENSG00000101812Homo sapiens
 H2BFSENSG00000234289Homo sapiens
 H2BFSENSG00000274559Homo sapiens
 H2BFWTENSG00000123569Homo sapiens
 O60814ENSG00000197903Homo sapiens
 P06899ENSG00000124635Homo sapiens
 P23527ENSG00000274641Homo sapiens
 P33778ENSG00000276410Homo sapiens
 P58876ENSG00000158373Homo sapiens
 P62807ENSG00000273802Homo sapiens
 P62807ENSG00000180596Homo sapiens
 P62807ENSG00000274290Homo sapiens
 P62807ENSG00000277224Homo sapiens
 P62807ENSG00000278588Homo sapiens
 Q16778ENSG00000184678Homo sapiens
 Q5QNW6ENSG00000203814Homo sapiens
 Q8N257ENSG00000196890Homo sapiens
 Q93079ENSG00000275713Homo sapiens
 Q99877ENSG00000233822Homo sapiens
 Q99879ENSG00000273703Homo sapiens
 Q99880ENSG00000185130Homo sapiens
 H2bfmENSMUSG00000048155Mus musculus
 P10853ENSMUSG00000095217Mus musculus
 P10853ENSMUSG00000069307Mus musculus
 P10853ENSMUSG00000094338Mus musculus
 P10853ENSMUSG00000069300Mus musculus
 P10853ENSMUSG00000069303Mus musculus
 P10853ENSMUSG00000069268Mus musculus
 P10854ENSMUSG00000114279Mus musculus
 Q64475ENSMUSG00000075031Mus musculus
 Q64478ENSMUSG00000114456Mus musculus
 Q64524ENSMUSG00000068854Mus musculus
 Q64525ENSMUSG00000105827Mus musculus
 Q6ZWY9ENSMUSG00000058385Mus musculus
 Q6ZWY9ENSMUSG00000047246Mus musculus
 Q6ZWY9ENSMUSG00000018102Mus musculus
 Q8CGP1ENSMUSG00000062727Mus musculus
 Q8CGP2ENSMUSG00000069308Mus musculus
 Q9D2U9ENSMUSG00000056895Mus musculus
 Q9D9Z7ENSMUSG00000045022Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
CU302436.1 / H2BFM* / H2BFS* / Q7Z2G1* / Q6ZWY9* / Q64525* / Q64524* / Q64478* / Q64475* / Q5QNW6* / Q16778* / P62807* / P58876* / P57053* / P33778* / P23527* / P10854* / P10853* / P0C1H6* ...ENSDARG0000011196449
CU302436.4 / H2BFM* / H2BFS* / Q7Z2G1* / Q6ZWY9* / Q64525* / Q64524* / Q64478* / Q64475* / Q5QNW6* / Q16778* / P62807* / P58876* / P57053* / P33778* / P23527* / P10854* / P10853* / P0C1H6* ...ENSDARG0000011419549
zgc:194989 / H2BFM* / H2BFS* / Q7Z2G1* / Q6ZWY9* / Q64525* / Q64524* / Q64478* / Q64475* / Q5QNW6* / Q16778* / P62807* / P58876* / P57053* / P33778* / P23527* / P10854* / P10853* / P0C1H6* ...ENSDARG0000011440549
CR354435.2 / H2BFM* / H2BFS* / Q7Z2G1* / Q6ZWY9* / Q64525* / Q64524* / Q64478* / Q64475* / Q5QNW6* / Q16778* / P62807* / P58876* / P57053* / P33778* / P23527* / P10854* / P10853* / P0C1H6* ...ENSDARG0000010973749
zgc:171759 / H2BFM* / H2BFS* / Q7Z2G1* / Q6ZWY9* / Q64525* / Q64524* / Q64478* / Q64475* / Q5QNW6* / Q16778* / P62807* / P58876* / P57053* / P33778* / P23527* / P10854* / P10853* / P0C1H6* ...ENSDARG0000011593849
zgc:112234 / H2BFM* / H2BFS* / Q7Z2G1* / Q6ZWY9* / Q64525* / Q64524* / Q64478* / Q64475* / Q5QNW6* / Q16778* / P62807* / P58876* / P57053* / P33778* / P23527* / P10854* / P10853* / P0C1H6* ...ENSDARG0000010539348
zgc:112234 / H2BFM* / H2BFS* / Q7Z2G1* / Q6ZWY9* / Q64525* / Q64524* / Q64478* / Q64475* / Q5QNW6* / Q16778* / P62807* / P58876* / P57053* / P33778* / P23527* / P10854* / P10853* / P0C1H6* ...ENSDARG0000010548348
Q5BJA5 / CR354435.1 / Histone H2B 1/2 / H2BFM* / H2BFS* / Q64478* / Q64475* / Q5QNW6* / Q16778* / P62807* / P58876* / P57053* / P33778* / P23527* / P10854* / P10853* / P0C1H6* / P06899* / ...ENSDARG0000007029748
hist1h2ba / histone cluster 1, H2ba / H2BFS* / H2BFM* / Q6ZWY9* / Q64525* / Q64524* / Q64478* / Q64475* / Q5QNW6* / Q16778* / P62807* / P58876* / P57053* / P33778* / P23527* / P10854* / P10...ENSDARG0000010937048
zgc:112234 / H2BFM* / H2BFS* / Q7Z2G1* / Q6ZWY9* / Q64525* / Q64524* / Q64478* / Q64475* / Q5QNW6* / Q16778* / P62807* / P58876* / P57053* / P33778* / P23527* / P10854* / P10853* / P0C1H6* ...ENSDARG0000010541448
si:dkey-23a13.22 / H2BFM* / H2BFS* / Q7Z2G1* / Q6ZWY9* / Q64525* / Q64524* / Q64478* / Q64475* / Q5QNW6* / Q16778* / P62807* / P58876* / P57053* / P33778* / P23527* / P10854* / P10853* / P0...ENSDARG0000010538448
zgc:112234 / H2BFM* / H2BFS* / Q7Z2G1* / Q6ZWY9* / Q64525* / Q64524* / Q64478* / Q64475* / Q5QNW6* / Q16778* / P62807* / P58876* / P57053* / P33778* / P23527* / P10854* / P10853* / P0C1H6* ...ENSDARG0000009951448
si:dkey-261m9.19 / H2BFM* / H2BFS* / Q7Z2G1* / Q6ZWY9* / Q64525* / Q64524* / Q64478* / Q64475* / Q5QNW6* / Q16778* / P62807* / P58876* / P57053* / P33778* / P23527* / P10854* / P10853* / P0...ENSDARG0000011412548
Q5BJA5 / zgc:173587 / H2BFM* / H2BFS* / Q64525* / Q64524* / Q64478* / Q64475* / Q5QNW6* / Q16778* / P62807* / P58876* / P57053* / P33778* / P23527* / P10854* / P10853* / P0C1H6* / P06899* /...ENSDARG0000007548248
si:ch211-113a14.22 / H2BFM* / H2BFS* / Q7Z2G1* / Q6ZWY9* / Q64525* / Q64524* / Q64478* / Q64475* / Q5QNW6* / Q16778* / P62807* / P58876* / P57053* / P33778* / P23527* / P10854* / P10853* / ...ENSDARG0000010539748
zgc:112234 / H2BFM* / H2BFS* / Q7Z2G1* / Q6ZWY9* / Q64525* / Q64524* / Q64478* / Q64475* / Q5QNW6* / Q16778* / P62807* / P58876* / P57053* / P33778* / P23527* / P10854* / P10853* / P0C1H6* ...ENSDARG0000010550748
zgc:171759 / H2BFM* / H2BFS* / Q7Z2G1* / Q6ZWY9* / Q64525* / Q64524* / Q64478* / Q64475* / Q5QNW6* / Q16778* / P62807* / P58876* / P57053* / P33778* / P23527* / P10854* / P10853* / P0C1H6* ...ENSDARG0000010025948
zgc:112234 / H2BFM* / H2BFS* / Q7Z2G1* / Q6ZWY9* / Q64525* / Q64524* / Q64478* / Q64475* / Q5QNW6* / Q16778* / P62807* / P58876* / P57053* / P33778* / P23527* / P10854* / P10853* / P0C1H6* ...ENSDARG0000011193448
si:ch211-113a14.22 / H2BFM* / H2BFS* / Q7Z2G1* / Q6ZWY9* / Q64525* / Q64524* / Q64478* / Q64475* / Q5QNW6* / Q16778* / P62807* / P58876* / P57053* / P33778* / P23527* / P10854* / P10853* / ...ENSDARG0000011489548
Q5BJA5 / FP236812.1 / Histone H2B 1/2 / H2BFM* / H2BFS* / P62807* / P58876* / P57053* / Q99877* / P23527* / P0C1H6* / P06899* / O60814* / H2BFWT* / Q99880* / Q99879* / P33778* / Q93079* / ...ENSDARG0000010450148


Protein motifs (from Interpro)
Interpro ID Name
 IPR000558  Histone H2B
 IPR002119  Histone H2A
 IPR007125  Histone H2A/H2B/H3
 IPR009072  Histone-fold
 IPR032454  Histone H2A, C-terminal domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006334 nucleosome assembly IBA
 cellular_componentGO:0000786 nucleosome IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005694 chromosome IEA
 molecular_functionGO:0003677 DNA binding IBA
 molecular_functionGO:0046982 protein heterodimerization activity IEA


Pathways (from Reactome)
Pathway description
PRC2 methylates histones and DNA
Condensation of Prophase Chromosomes
Oxidative Stress Induced Senescence
Senescence-Associated Secretory Phenotype (SASP)
HATs acetylate histones
SIRT1 negatively regulates rRNA expression
NoRC negatively regulates rRNA expression
B-WICH complex positively regulates rRNA expression
Transcriptional regulation by small RNAs
Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3
Ub-specific processing proteases
Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks
Nonhomologous End-Joining (NHEJ)
Processing of DNA double-strand break ends
G2/M DNA damage checkpoint
RNA Polymerase I Promoter Opening
RNA Polymerase I Chain Elongation
E3 ubiquitin ligases ubiquitinate target proteins
RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function
Estrogen-dependent gene expression


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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