ENSMUSG00000076612


Mus musculus

Features
Gene ID: ENSMUSG00000076612
  
Biological name :Ighg2c
  
Synonyms : Ighg2c
  
Possible biological names infered from orthology : IGHG1 / IGHG2 / IGHG3 / IGHG4 / immunoglobulin heavy constant gamma 1 (G1m marker) / immunoglobulin heavy constant gamma 2 (G2m marker) / immunoglobulin heavy constant gamma 3 (G3m marker) / immunoglobulin heavy constant gamma 4 (G4m marker) / P01857 / P01859 / P01861
  
Species: Mus musculus
  
Chr. number: 12
Strand: -1
Band: F1
Gene start: 113285325
Gene end: 113288932
  
Corresponding Affymetrix probe sets: 1425385_a_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000100212
Ensembl peptide - ENSMUSP00000142282
MGI - MGI:2686979
swissprot - A0A0A6YY53
swissprot - F6TQW2
Ensembl - ENSMUSG00000076612
  
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ighv1-4ENSDARG00000096355Danio rerio
 IGHG1ENSG00000211896Homo sapiens
 IGHG2ENSG00000211893Homo sapiens
 IGHG3ENSG00000211897Homo sapiens
 IGHG4ENSG00000211892Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Ighg2b / IGHG1* / IGHG2* / IGHG3* / IGHG4* / P01861* / P01857* / P01859* / immunoglobulin heavy constant gamma 4 (G4m marker)* / immunoglobulin heavy constant gamma 1 (G1m marker)* / immuno...ENSMUSG0000007661375
Ighg3 / IGHG1* / IGHG2* / IGHG4* / P01861* / P01857* / P01859* / immunoglobulin heavy constant gamma 4 (G4m marker)* / immunoglobulin heavy constant gamma 1 (G1m marker)* / immunoglobulin h...ENSMUSG0000007661567
Ighg1 / IGHG2* / IGHG3* / IGHG4* / P01861* / P01857* / P01859* / immunoglobulin heavy constant gamma 4 (G4m marker)* / immunoglobulin heavy constant gamma 1 (G1m marker)* / immunoglobulin h...ENSMUSG0000007661467
Ighe / P01854* / immunoglobulin heavy constant epsilon*ENSMUSG0000008764235
Ighm / immunoglobulin heavy constant mu / P01871*ENSMUSG0000007661727
Igha / IGHA1* / IGHA2* / P01877* / P01876* / immunoglobulin heavy constant alpha 1* / immunoglobulin heavy constant alpha 2 (A2m marker)*ENSMUSG0000009507925


Protein motifs (from Interpro)
Interpro ID Name
No match


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0002455 humoral immune response mediated by circulating immunoglobulin IDA
 biological_processGO:0006910 phagocytosis, recognition IBA
 biological_processGO:0006911 phagocytosis, engulfment IBA
 biological_processGO:0006958 complement activation, classical pathway IBA
 biological_processGO:0016064 immunoglobulin mediated immune response IDA
 biological_processGO:0019731 antibacterial humoral response IDA
 biological_processGO:0042742 defense response to bacterium IDA
 biological_processGO:0045087 innate immune response IBA
 biological_processGO:0050853 B cell receptor signaling pathway IBA
 biological_processGO:0050871 positive regulation of B cell activation IBA
 cellular_componentGO:0005615 extracellular space IDA
 cellular_componentGO:0009897 external side of plasma membrane IBA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0042571 immunoglobulin complex, circulating IDA
 cellular_componentGO:0072562 blood microparticle IBA
 molecular_functionGO:0003823 antigen binding IDA
 molecular_functionGO:0034987 immunoglobulin receptor binding IBA


Pathways (from Reactome)
Pathway description
Initial triggering of complement
Classical antibody-mediated complement activation
FCGR activation
Regulation of actin dynamics for phagocytic cup formation
Role of phospholipids in phagocytosis
Regulation of Complement cascade


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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