ENSMUSG00000079614


Mus musculus

Features
Gene ID: ENSMUSG00000079614
  
Biological name :Seh1l
  
Synonyms : Nucleoporin SEH1 / Q8R2U0 / Seh1l
  
Possible biological names infered from orthology : Q96EE3 / SEH1 like nucleoporin
  
Species: Mus musculus
  
Chr. number: 18
Strand: 1
Band: E1
Gene start: 67774876
Gene end: 67795461
  
Corresponding Affymetrix probe sets: 10456423 (MoGene1.0st)   1419967_at (Mouse Genome 430 2.0 Array)   1420386_at (Mouse Genome 430 2.0 Array)   1424199_at (Mouse Genome 430 2.0 Array)   1424200_s_at (Mouse Genome 430 2.0 Array)   1424201_a_at (Mouse Genome 430 2.0 Array)   1424202_at (Mouse Genome 430 2.0 Array)   1441857_x_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000025421
NCBI entrez gene - 72124     See in Manteia.
MGI - MGI:1919374
RefSeq - XM_006526278
RefSeq - NM_001039088
RefSeq - NM_028112
RefSeq Peptide - NP_082388
RefSeq Peptide - NP_001034177
swissprot - Q8R2U0
Ensembl - ENSMUSG00000079614
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 seh1lENSDARG00000004280Danio rerio
 SEH1LENSGALG00000013872Gallus gallus
 SEH1LENSG00000085415Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR001680  WD40 repeat
 IPR015943  WD40/YVTN repeat-like-containing domain superfamily
 IPR017986  WD40-repeat-containing domain
 IPR020472  G-protein beta WD-40 repeat
 IPR036322  WD40-repeat-containing domain superfamily
 IPR037363  Sec13/Seh1 family
 IPR037597  Nucleoporin Seh1


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0002534 cytokine production involved in inflammatory response IMP
 biological_processGO:0006999 nuclear pore organization IEA
 biological_processGO:0007049 cell cycle IEA
 biological_processGO:0007059 chromosome segregation IEA
 biological_processGO:0007080 mitotic metaphase plate congression IEA
 biological_processGO:0015031 protein transport IEA
 biological_processGO:0032008 positive regulation of TOR signaling IEA
 biological_processGO:0034198 cellular response to amino acid starvation IEA
 biological_processGO:0034629 cellular protein-containing complex localization IEA
 biological_processGO:0050830 defense response to Gram-positive bacterium IMP
 biological_processGO:0051028 mRNA transport IEA
 biological_processGO:0051301 cell division IEA
 biological_processGO:0051315 attachment of mitotic spindle microtubules to kinetochore IEA
 biological_processGO:1904263 positive regulation of TORC1 signaling ISO
 cellular_componentGO:0000775 chromosome, centromeric region IEA
 cellular_componentGO:0000776 kinetochore ISO
 cellular_componentGO:0000777 condensed chromosome kinetochore IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005643 nuclear pore IEA
 cellular_componentGO:0005694 chromosome IEA
 cellular_componentGO:0005764 lysosome IEA
 cellular_componentGO:0005765 lysosomal membrane ISO
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0031080 nuclear pore outer ring IEA
 cellular_componentGO:0061700 GATOR2 complex IEA
 molecular_functionGO:0003674 molecular_function ND
 molecular_functionGO:0005198 structural molecule activity IEA
 molecular_functionGO:0005515 protein binding IEA
 molecular_functionGO:0017056 structural constituent of nuclear pore IEA


Pathways (from Reactome)
Pathway description
Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal
Transport of Mature mRNA derived from an Intron-Containing Transcript
Regulation of Glucokinase by Glucokinase Regulatory Protein
snRNP Assembly
Separation of Sister Chromatids
Resolution of Sister Chromatid Cohesion
SUMOylation of DNA damage response and repair proteins
SUMOylation of ubiquitinylation proteins
Nuclear Pore Complex (NPC) Disassembly
Regulation of HSF1-mediated heat shock response
SUMOylation of SUMOylation proteins
SUMOylation of chromatin organization proteins
SUMOylation of RNA binding proteins
SUMOylation of DNA replication proteins
Transcriptional regulation by small RNAs
RHO GTPases Activate Formins
Mitotic Prometaphase


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0011100 complete preweaning lethality "death of all organisms of a given genotype in a population between fertilization and weaning age (Mus: approximately 3-4 weeks of age)" [MGI:csmith]
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Allelic Composition: Rpgrip1ltm1a(EUCOMM)Wtsi/Rpgrip1ltm1a(EUCOMM)Wtsi
Genetic Background: C57BL/6N-Rpgrip1ltm1a(EUCOMM)Wtsi/Wtsi

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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