Manteia - Molecule gene

ENSMUSG00000102439

Mus musculus

Features

Gene ID:	ENSMUSG00000102439

Biological name :	Flg

Synonyms :	Flg

Possible biological names infered from orthology :	filaggrin / P20930

Species:	Mus musculus

Chr. number:	3
Strand:	1
Band:	F2.1
Gene start:	93273523
Gene end:	93293686

Corresponding Affymetrix probe sets:	10405935 (MoGene1.0st) 10493925 (MoGene1.0st) 1427268_at (Mouse Genome 430 2.0 Array)

Cross references:	Ensembl peptide - ENSMUSP00000141273 Ensembl peptide - ENSMUSP00000142294 Ensembl peptide - ENSMUSP00000142003 Ensembl peptide - ENSMUSP00000141987 Ensembl peptide - ENSMUSP00000141981 Ensembl peptide - ENSMUSP00000141844 Ensembl peptide - ENSMUSP00000141513 Ensembl peptide - ENSMUSP00000141392 NCBI entrez gene - 14246 See in Manteia. MGI - MGI:95553 swissprot - A0A0A6YXI5 swissprot - A0A0A6YXH0 swissprot - A0A0A6YXG4 swissprot - A0A0A6YY62 swissprot - A0A0A6YWE2 swissprot - A0A0A6YW46 swissprot - A0A0A6YVU7 swissprot - A0A0A6YX57 Ensembl - ENSMUSG00000102439

See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed

Ortholog prediction (from Ensembl)

Ortholog name	ID	Species
CRNN	ENSGALG00000027316	Gallus gallus
FLG	ENSG00000143631	Homo sapiens

Paralog prediction (from Ensembl)

Paralog name	ID	Similarity(%)
Hrnr / Q86YZ3* / hornerin*	ENSMUSG00000041991	27
Flg2 / filaggrin-2 / Q5D862* / filaggrin family member 2*	ENSMUSG00000049133	26
Rptn / P97347 / Repetin / Q6XPR3*	ENSMUSG00000041984	20
Tchh / Q07283* / trichohyalin*	ENSMUSG00000052415	19
Q9D3P1 / Tchhl1 / Trichohyalin-like protein 1 / Q5QJ38* / trichohyalin like 1*	ENSMUSG00000027908	16
Crnn / cornulin / Q9UBG3*	ENSMUSG00000078657	15

Protein motifs (from Interpro)

Interpro ID	Name
IPR001751	S100/Calbindin-D9k, conserved site
IPR002048	EF-hand domain
IPR003303	Filaggrin
IPR011992	EF-hand domain pair
IPR013787	S100/CaBP-9k-type, calcium binding, subdomain
IPR018247	EF-Hand 1, calcium-binding site
IPR034325	S-100

Gene Ontology (GO)

Type	GO ID	Term	Ev.Code
molecular_function	GO:0005198	structural molecule activity	IEA
molecular_function	GO:0005509	calcium ion binding	IEA
molecular_function	GO:0046872	metal ion binding	IEA
molecular_function	GO:0046914	transition metal ion binding	IEA

Pathways (from Reactome)

Pathway description

Formation of the cornified envelope

Phenotype (from MGI, Zfin or HPO)

ID	Phenotype	Definition	Genetic BG
MP:0000018	small ears	"outer ears of a smaller than normal size" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]	Show Allelic Composition: Clip1^tm1Gal/Clip1^tm1Gal Genetic Background: involves: 129P2/OlaHsd * C57BL/6
MP:0000019	thick ears	"increased width of the epidermal and cartilaginous tissue that makes up the ear" [J:65045]	Show Allelic Composition: Clip1^tm1Gal/Clip1^tm1Gal Genetic Background: involves: 129P2/OlaHsd * C57BL/6
MP:0000367	abnormal coat/ hair morphology	"anomalous color, structure, growth, or texture of the hair" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]	Show Allelic Composition: Dido1^tm1Cmar/Dido1⁺ Genetic Background: involves: 129S1/Sv * 129X1/SvJ
MP:0000414	alopecia	"absence of hair or loss of hair; not usually in reference to primary genetic hairlessness but may be due to dietary, stress, secondary to immune condition" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, J:30772, J:33796]	Show Allelic Composition: Flg^ft/Flg^ft,Tmem79^ma/Tmem79^ma Genetic Background: involves: C57BL/6J * CBA/CaGr Allelic Composition: Flg^ft/Flg^ft,Tmem79^ma/Tmem79^ma Genetic Background: involves: CBA/CaGr
MP:0001192	scaly skin	"skin covered with shedding scales or flakes" [J:65146]	Show Allelic Composition: Flg^ft/Flg^ft Genetic Background: involves: C57BL/6 Allelic Composition: Flg^tm1Amag/Flg^tm1Amag Genetic Background: involves: 129S6/SvEvTac * BALB/c * C57BL/6NTac Allelic Composition: Flg^ft/Flg^ft Genetic Background: STOCK a/a Tmem79^ma Flg^ft/J Allelic Composition: Flg^ft/Flg^ft,Tmem79^ma/Tmem79^ma Genetic Background: involves: CBA/CaGr
MP:0001194	dermatitis	"inflammation of the skin" [J:65146]	Show Allelic Composition: Limk2^{Gt(OST80053)Lex}/Limk2^{Gt(OST80053)Lex} Genetic Background: involves: 129S5/SvEvBrd * C57BL/6 Allelic Composition: Flg^tm1Amag/Flg^tm1Amag Genetic Background: involves: 129S6/SvEvTac * BALB/c * C57BL/6NTac Allelic Composition: Flg^ft/Flg^ft Genetic Background: STOCK a/a Tmem79^ma Flg^ft/J
MP:0001195	flaky skin	"shedding scales on the skin " [J:56641]	Show Allelic Composition: Clip1^tm1Gal/Clip1^tm1Gal Genetic Background: involves: 129P2/OlaHsd * C57BL/6 Allelic Composition: Flg^ft/Flg^ft Genetic Background: STOCK a/a Tmem79^ma Flg^ft/J
MP:0001196	shiny skin	"skin with a glossy or glistening appearance" [J:56641]	Show Allelic Composition: Flg^tm1Amag/Flg^tm1Amag Genetic Background: involves: 129S6/SvEvTac * BALB/c * C57BL/6NTac
MP:0001212	skin lesions	"focal patches of inflammation on the skin" [J:30162]	Show Allelic Composition: Flg^tm1Amag/Flg^tm1Amag Genetic Background: involves: 129S6/SvEvTac * BALB/c * C57BL/6NTac
MP:0001216	abnormal epidermal layer morphology	"anomalous structure or development of the superficial epithelial portion of the skin" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]	Show Allelic Composition: Flg^ft/Flg^ft Genetic Background: involves: C57BL/6
MP:0001219	thickened epidermis	"increase in the width of the epidermal cell layer in the skin" [J:65146]	Show Allelic Composition: Flg^ft/Flg^ft Genetic Background: STOCK a/a Tmem79^ma Flg^ft/J
MP:0001230	epidermal desquamation	"shedding of the cuticle of the epidermis in scales or shreds" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:56777]	Show Allelic Composition: Tcirg1^M1Jeau/Tcirg1⁺ Genetic Background: either: (involves: C3H/HeJ * C57BL/6) or (involves: C3H/HeJ * C57BL/6 * FVB/N)
MP:0001239	abnormal granular layer morphology	"structural or developmental anomaly of the layer of flattened cells containing basophilic granules of keratohyalin and lying just above the stratum spinosum (spiny layer) of the epidermis" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]	Show Allelic Composition: Clip1^tm1Gal/Clip1^tm1Gal Genetic Background: involves: 129P2/OlaHsd * C57BL/6
MP:0001240	abnormal cornified layer morphology	"structural or developmental anomaly of the outer layer of the epidermis, consisting of several layers of flat keratinized non-nucleated cells" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]	Show Allelic Composition: Tcirg1^M1Jeau/Tcirg1⁺ Genetic Background: either: (involves: C3H/HeJ * C57BL/6) or (involves: C3H/HeJ * C57BL/6 * FVB/N)
MP:0001242	hyperkeratosis	"increased depth of the corneal layer of the epidermis; thickening of the horny layer of the epidermis" [J:1133]	Show Allelic Composition: Clip1^tm1Gal/Clip1^tm1Gal Genetic Background: involves: 129P2/OlaHsd * C57BL/6 Allelic Composition: Flg^tm1Amag/Flg^tm1Amag Genetic Background: involves: 129S6/SvEvTac * BALB/c * C57BL/6NTac Allelic Composition: Flg^ft/Flg^ft Genetic Background: STOCK a/a Tmem79^ma Flg^ft/J
MP:0001265	reduced body size	"smaller than average body weight, height and/or length of an organism compared to controls" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, J:23170]	Show Allelic Composition: Clip1^tm1Gal/Clip1^tm1Gal Genetic Background: involves: 129P2/OlaHsd * C57BL/6
MP:0001510	abnormal coat appearance	"coat that looks different from the usual state " [Stedman s Medical Dictionary:ISBN 0-683-40008-8]	Show Allelic Composition: Flg^ft/Flg^ft,Tmem79^ma/Tmem79^ma Genetic Background: involves: C57BL/6J * CBA/CaGr Allelic Composition: Flg^ft/Flg^ft,Tmem79^ma/Tmem79^ma Genetic Background: involves: CBA/CaGr
MP:0001547	abnormal lipid level	"anomalous concentrations of fat-soluble substances (molecules composed of carbon and hydrogen and are characteristically insoluble in water) in the body" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]	Show Allelic Composition: Tcirg1^M1Jeau/Tcirg1⁺ Genetic Background: either: (involves: C3H/HeJ * C57BL/6) or (involves: C3H/HeJ * C57BL/6 * FVB/N)
MP:0001800	abnormal humoral immune response	"abnormal immune function mediated by antibodies" [Immunobiology , The Immune System in Health and Disease:ISBN 0-8153-1691-7]	Show Allelic Composition: Tcirg1^M1Jeau/Tcirg1⁺ Genetic Background: either: (involves: C3H/HeJ * C57BL/6) or (involves: C3H/HeJ * C57BL/6 * FVB/N)
MP:0001874	acanthosis	"diffuse hyperplasia of the spinous layer of the skin" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]	Show Allelic Composition: Clip1^tm1Gal/Clip1^tm1Gal Genetic Background: involves: 129P2/OlaHsd * C57BL/6 Allelic Composition: Flg^ft/Flg^ft Genetic Background: involves: C57BL/6 Allelic Composition: Flg^ft/Flg^ft Genetic Background: B6.Cg-Flg^ft Allelic Composition: Flg^ft/Flg^ft Genetic Background: STOCK a/a Tmem79^ma Flg^ft/J Allelic Composition: Flg^ft/Flg^ft,Tmem79^ma/Tmem79^ma Genetic Background: involves: CBA/CaGr
MP:0002060	abnormal skin morphology	"malformation or atypical structure of the membranous protective covering of the body" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, J:56777]	Show Allelic Composition: Tcirg1^M1Jeau/Tcirg1⁺ Genetic Background: either: (involves: C3H/HeJ * C57BL/6) or (involves: C3H/HeJ * C57BL/6 * FVB/N) Allelic Composition: Flg^ft/Flg^ft Genetic Background: STOCK a/a Tmem79^ma Flg^ft/J
MP:0002082	postnatal lethality	"premature death anytime after postnatal day 1 to weaning age (3 weeks)" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]	Show Allelic Composition: Clip1^tm1Gal/Clip1^tm1Gal Genetic Background: involves: 129P2/OlaHsd * C57BL/6
MP:0002493	increased IgG	"greater than normal immunoglobulin class G level" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]	Show Allelic Composition: Flg^ft/Flg^ft Genetic Background: B6.Cg-Flg^ft
MP:0002497	increased IgE	"greater than normal immunoglobulin class E level" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]	Show Allelic Composition: Flg^ft/Flg^ft Genetic Background: B6.Cg-Flg^ft Allelic Composition: Flg^tm1Amag/Flg^tm1Amag Genetic Background: involves: 129S6/SvEvTac * BALB/c * C57BL/6NTac Allelic Composition: Flg^ft/Flg^ft,Tmem79^ma/Tmem79^ma Genetic Background: involves: CBA/CaGr
MP:0002796	impaired skin barrier function	"impaired ability of the skin to regulate water loss; frequently leads to dehydration" [J:56641]	Show Allelic Composition: Flg^ft/Flg^ft Genetic Background: B6.Cg-Flg^ft Allelic Composition: Flg^ft/Flg^ft Genetic Background: Not Specified Allelic Composition: Flg^ft/Flg^ft,Tmem79^ma/Tmem79^ma Genetic Background: involves: CBA/CaGr
MP:0003809	abnormal hair shaft morphology	"irregular or unusual structure of the cuticle, and/or cortex and/or medulla of a hair" [llw2:Linda Washburn , Mouse Genome Informatics Curator]	Show Allelic Composition: Flg^ft/Flg^ft,Tmem79^ma/Tmem79^ma Genetic Background: involves: C57BL/6J * CBA/CaGr
MP:0003810	abnormal hair cuticle	"anomalies in the thin, smooth and glossy outer protective cell layer of hair shaft" [llw2:Linda Washburn , Mouse Genome Informatics Curator]	Show Allelic Composition: Flg^ft/Flg^ft Genetic Background: B6.Cg-Flg^ft Allelic Composition: Flg^ft/Flg^ft,Tmem79^ma/Tmem79^ma Genetic Background: involves: CBA/CaGr
MP:0003846	matted coat	"coat hairs sticks together to form clumps and does not lie flat" [llw2:Linda Washburn , Mouse Genome Informatics Curator]	Show Allelic Composition: Flg^ft/Flg^ft,Tmem79^ma/Tmem79^ma Genetic Background: involves: C57BL/6J * CBA/CaGr Allelic Composition: Flg^ft/Flg^ft,Tmem79^ma/Tmem79^ma Genetic Background: involves: CBA/CaGr
MP:0003848	brittle hair	"hair is susceptible to breakage " [llw2:Linda Washburn , Mouse Genome Informatics Curator]	Show Allelic Composition: Flg^ft/Flg^ft,Tmem79^ma/Tmem79^ma Genetic Background: involves: CBA/CaGr
MP:0003853	dry skin	"skin characterized by the lack of natural or normal moisture" [monikat:Monika Tomczuk, Mouse Genome Informatics Curator]	Show Allelic Composition: Flg^ft/Flg^ft Genetic Background: B6.Cg-Flg^ft Allelic Composition: Flg^tm1Amag/Flg^tm1Amag Genetic Background: involves: 129S6/SvEvTac * BALB/c * C57BL/6NTac Allelic Composition: Flg^ft/Flg^ft,Tmem79^ma/Tmem79^ma Genetic Background: involves: CBA/CaGr
MP:0003982	increased cholesterol level	"greater than normal concentration in the body of these most abundant steroids in animal tissues, and precursors to steroid hormones and bile salts; also components of plasma membranes" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]	Show Allelic Composition: Flg^tm1Amag/Flg^tm1Amag Genetic Background: involves: 129S6/SvEvTac * BALB/c * C57BL/6NTac
MP:0004947	skin inflammation	"local accumulation of fluid, plasma proteins, and leukocytes in the skin" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]	Show Allelic Composition: Flg^ft/Flg^ft Genetic Background: involves: C57BL/6 Allelic Composition: Flg^ft/Flg^ft,Tmem79^ma/Tmem79^ma Genetic Background: involves: CBA/CaGr
MP:0005251	blepharitis	"inflammation of the eyelids" [MeSH:National Library of Medicine - Medical Subject Headings , 2003]	Show Allelic Composition: Flg^ft/Flg^ft,Tmem79^ma/Tmem79^ma Genetic Background: involves: CBA/CaGr
MP:0005501	abnormal skin physiology	"atypical function of the membranous protective covering of the body" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, Stedman s Medical Dictionary:ISBN 0-683-40008-8]	Show Allelic Composition: Flg^ft/Flg^ft Genetic Background: STOCK a/a Tmem79^ma Flg^ft/J
MP:0005617	increased susceptibility to type IV hypersensitivity reaction	"greater likelihood of developing an antigen-elicited cellular immune reaction that results in tissue damage, but does not require Ab participation; the response is seen at the area of contact " [Pathology:ISBN 0-397-51047-0, cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]	Show Allelic Composition: Flg^tm1Amag/Flg^tm1Amag Genetic Background: involves: 129S6/SvEvTac * BALB/c * C57BL/6NTac
MP:0008499	increased IgG1 level	"greater than normal immunoglobulin class G1 level" [MGI:tmeehan "Terry Meehan, Mouse Genome Informatics Curator"]	Show Allelic Composition: Flg^ft/Flg^ft Genetic Background: B6.Cg-Flg^ft Allelic Composition: Flg^tm1Amag/Flg^tm1Amag Genetic Background: involves: 129S6/SvEvTac * BALB/c * C57BL/6NTac
MP:0008500	increased IgG2a level	"greater than normal immunoglobulin class G2a level" [MGI:tmeehan "Terry Meehan, Mouse Genome Informatics Curator"]	Show Allelic Composition: Flg^ft/Flg^ft Genetic Background: B6.Cg-Flg^ft
MP:0008566	increased interferon-gamma secretion	"increase in the production or release of the major interferon produced by mitogenically or antigenically stimulated lymphocytes that is involved in immunoregulation" [MESH:D12.644.276.374.440.893]	Show Allelic Composition: Flg^ft/Flg^ft Genetic Background: B6.Cg-Flg^ft
MP:0008660	increased interleukin-10 secretion	"increase in the production or release of a cytokine produced by a variety of cell types, including T-cells, monocytes, dendritic cells and epithelial cells that exerts a variety of effects on immunoregulation and inflammation" [MESH:D12.644.276.374.465.510]	Show Allelic Composition: Flg^ft/Flg^ft Genetic Background: B6.Cg-Flg^ft
MP:0008672	increased interleukin-13 secretion	"increase in the production or release of a cytokine synthesized by T-cells that produces proliferation, immunoglobulin isotype switching, and immunoglobulin production by immature B-cells, and appears to play a role in regulating inflammatory and immune responses" [MESH:D12.644.276.374.465.513]	Show Allelic Composition: Flg^ft/Flg^ft Genetic Background: B6.Cg-Flg^ft
MP:0008681	increased interleukin-17 secretion	"increase in the production or release of a proinflammatory cytokine produced primarily by T-cells or their precursors" [MESH:D12.644.276.374.465.517]	Show Allelic Composition: Flg^ft/Flg^ft Genetic Background: B6.Cg-Flg^ft
MP:0008699	increased interleukin-4 secretion	"increase in the production or release of a soluble factor produced by activated T-cells that induces the expression of MHC class II genes and FC receptors on B-cells and causes their proliferation and differentiation; it also acts on T-cells, mast cells and several other hematopoietic lineage cells" [MESH:D12.644.276.374.465.504]	Show Allelic Composition: Flg^ft/Flg^ft Genetic Background: B6.Cg-Flg^ft
MP:0008702	increased interleukin-5 secretion	"increase in the production or release of a cytokine that promotes differentiation and activation of eosinophils; it also triggers activated B-cells to differentiate into immunoglobulin-secreting cells" [MESH:D12.644.276.374.465.505]	Show Allelic Composition: Flg^ft/Flg^ft Genetic Background: B6.Cg-Flg^ft
MP:0008713	abnormal cytokine level	"deviation from the normal levels of any of the non-antibody proteins made by inflammatory leukocytes and some non-leukocytic cells that affect the behavior of other cells" [ISBN:0-8153-1691-7 "Immunobiology, The Immune System in Health and Disease", MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]	Show Allelic Composition: Flg^ft/Flg^ft Genetic Background: STOCK a/a Tmem79^ma Flg^ft/J
MP:0009336	increased splenocyte proliferation	"increase in the expansion rate of a splenocyte cell population by cell division" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]	Show Allelic Composition: Flg^ft/Flg^ft Genetic Background: B6.Cg-Flg^ft
MP:0009598	thin epidermis stratum granulosum	"decreased thickness of the layer of flattened cells containing basophilic granules of keratohyalin and lying just above the stratum spinosum (spiny layer) of the epidermis" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"]	Show Allelic Composition: Flg^ft/Flg^ft Genetic Background: STOCK a/a Tmem79^ma Flg^ft/J
MP:0009605	decreased keratohyalin granule number	"reduced number of the irregularly shaped basophilic granules in the cells of the stratum granulosum of the epidermis that may play a role in keratinization and barrier function" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition", MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]	Show Allelic Composition: Flg^tm1Amag/Flg^tm1Amag Genetic Background: involves: 129S6/SvEvTac * BALB/c * C57BL/6NTac
MP:0009675	orthokeratosis	"thickening of the stratum corneum of the epidermis (hyperkeratosis) with non-nucleated keratinocytes retained in this layer" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition", MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]	Show Allelic Composition: Flg^ft/Flg^ft Genetic Background: involves: C57BL/6 Allelic Composition: Flg^ft/Flg^ft Genetic Background: B6.Cg-Flg^ft Allelic Composition: Flg^ft/Flg^ft,Tmem79^ma/Tmem79^ma Genetic Background: involves: CBA/CaGr
MP:0009795	epidermal spongiosis	"intercellular edema within the epidermis" [MGI:llw2 "Linda Washburn, Mouse Genome Informatics Curator"]	Show Allelic Composition: Flg^ft/Flg^ft Genetic Background: STOCK a/a Tmem79^ma Flg^ft/J
MP:0009801	abnormal hair cortex keratinization	"any defect in the formation of the fibrous elements found in the hair cortex comprising acidic (Type I ) and basic (Type II) proteins that give hair such aspects as resilience, and elasticity" [ISBN:0-8493-8372-2 "Sundberg, JP (ed.) Handbook of Mouse Mutations with Skin and Hair Abnormalities", MGI:llw2 "Linda Washburn, Mouse Genome Informatics Curator"]	Show Allelic Composition: Flg^ft/Flg^ft,Tmem79^ma/Tmem79^ma Genetic Background: involves: CBA/CaGr
MP:0009931	abnormal skin appearance	"skin that looks different from the usual state" [MGI:llw2 "Linda Washburn, Mouse Genome Informatics Curator"]	Show Allelic Composition: Clip1^tm1Gal/Clip1^tm1Gal Genetic Background: involves: 129P2/OlaHsd * C57BL/6 Allelic Composition: Flg^ft/Flg^ft,Tmem79^ma/Tmem79^ma Genetic Background: involves: CBA/CaGr
MP:0010686	abnormal hair follicle matrix region morphology	"any structural anomaly of the bulb region adjacent to the dermal papilla that contains rapidly proliferating matrix cells that give rise to the various cell lineages of the hair shaft and inner root sheath" [PMID:19211055]	Show Allelic Composition: Flg^ft/Flg^ft,Tmem79^ma/Tmem79^ma Genetic Background: involves: C57BL/6J * CBA/CaGr
MP:0012078	abnormal tail ring morphology	"any structural anomaly of the segmentally patterned skin ridges appearing on the tail of rodents" [MGI:csmith]	Show Allelic Composition: Clip1^tm1Gal/Clip1^tm1Gal Genetic Background: involves: 129P2/OlaHsd * C57BL/6
MP:0013178	tail necrosis	"morphological changes resulting from pathological death of tail tissue; usually due to irreversible damage" [MGI:anna]	Show Allelic Composition: Clip1^tm1Gal/Clip1^tm1Gal Genetic Background: involves: 129P2/OlaHsd * C57BL/6
MP:0020084	short ears	"reduced length of the ears" [GOC:NV]	Show Allelic Composition: Clip1^tm1Gal/Clip1^tm1Gal Genetic Background: involves: 129P2/OlaHsd * C57BL/6

Interacting proteins (from Reactome)

Interactor ID

Name

Interaction type

No match

0 s.

External programs and data are copyrighted by and are the property of their respective authors. The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation
		© Olivier Tassy / Olivier Pourquie 2007-2024 contact: otassy@igbmc.fr