ENSMUSG00000109350


Mus musculus

Features
Gene ID: ENSMUSG00000109350
  
Biological name :Gm44805
  
Synonyms : Gm44805 / predicted gene 44805 / Q05020
  
Possible biological names infered from orthology : APOC2 / apolipoprotein C2 / P02655
  
Species: Mus musculus
  
Chr. number: 7
Strand: -1
Band: A3
Gene start: 19671584
Gene end: 19681423
  
Corresponding Affymetrix probe sets: 10560608 (MoGene1.0st)   1418069_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000114512
Ensembl peptide - ENSMUSP00000118305
NCBI entrez gene - 105886299     See in Manteia.
MGI - MGI:5753381
RefSeq - NM_001309799
RefSeq Peptide - NP_001296728
swissprot - Q05020
swissprot - Q3UJG0
Ensembl - ENSMUSG00000109350
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 APOC2ENSG00000234906Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Apoc2 / Q05020 / Apolipoprotein C-II / P02655* / apolipoprotein C2*ENSMUSG00000002992100


Protein motifs (from Interpro)
Interpro ID Name
 IPR008019  Apolipoprotein C-II


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006629 lipid metabolic process IEA
 biological_processGO:0006869 lipid transport IEA
 biological_processGO:0010518 positive regulation of phospholipase activity ISO
 biological_processGO:0010898 positive regulation of triglyceride catabolic process ISO
 biological_processGO:0010916 negative regulation of very-low-density lipoprotein particle clearance ISO
 biological_processGO:0016042 lipid catabolic process IEA
 biological_processGO:0032375 negative regulation of cholesterol transport ISO
 biological_processGO:0033344 cholesterol efflux ISO
 biological_processGO:0033700 phospholipid efflux ISO
 biological_processGO:0034382 chylomicron remnant clearance ISO
 biological_processGO:0034384 high-density lipoprotein particle clearance ISO
 biological_processGO:0043085 positive regulation of catalytic activity IEA
 biological_processGO:0043086 negative regulation of catalytic activity IEA
 biological_processGO:0045723 positive regulation of fatty acid biosynthetic process ISO
 biological_processGO:0045833 negative regulation of lipid metabolic process ISO
 biological_processGO:0048261 negative regulation of receptor-mediated endocytosis ISO
 biological_processGO:0051006 positive regulation of lipoprotein lipase activity ISO
 biological_processGO:0060697 positive regulation of phospholipid catabolic process ISO
 biological_processGO:0070328 triglyceride homeostasis ISO
 cellular_componentGO:0005576 extracellular region TAS
 cellular_componentGO:0005615 extracellular space ISO
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0034361 very-low-density lipoprotein particle ISO
 cellular_componentGO:0034362 low-density lipoprotein particle ISO
 cellular_componentGO:0034363 intermediate-density lipoprotein particle ISO
 cellular_componentGO:0034364 high-density lipoprotein particle IEA
 cellular_componentGO:0034366 spherical high-density lipoprotein particle ISO
 cellular_componentGO:0042627 chylomicron ISO
 molecular_functionGO:0008047 enzyme activator activity IEA
 molecular_functionGO:0008289 lipid binding ISO
 molecular_functionGO:0016004 phospholipase activator activity ISO
 molecular_functionGO:0042803 protein homodimerization activity ISO
 molecular_functionGO:0043274 phospholipase binding ISO
 molecular_functionGO:0055102 lipase inhibitor activity ISO
 molecular_functionGO:0060230 lipoprotein lipase activator activity ISO


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSMUSG00000002985 Apoe / P08226 / Apolipoprotein E / P02649*  / complex / reaction
 ENSMUSG00000032081 Apoc3 / apolipoprotein C-III isoform c / P02656* / apolipoprotein C3*  / complex / reaction






 

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