ENSDARG00000001769


Danio rerio

Features
Gene ID: ENSDARG00000001769
  
Biological name :ptpra
  
Synonyms : protein tyrosine phosphatase, receptor type, A / ptpra
  
Possible biological names infered from orthology : P18052 / P18433
  
Species: Danio rerio
  
Chr. number: 21
Strand: 1
Band:
Gene start: 15756549
Gene end: 15816317
  
Corresponding Affymetrix probe sets: Dr.8174.1.S1_at (Zebrafish Array)   NM_131888_at (Zebrafish Genome Array with custom cdf files)   
  
Cross references: Ensembl peptide - ENSDARP00000092731
Ensembl peptide - ENSDARP00000003403
NCBI entrez gene - 140818     See in Manteia.
RefSeq - NM_131888
RefSeq Peptide - NP_571963
swissprot - F1QE38
swissprot - F1QAX7
ZFIN ID - ZDB-GENE-020107-1
Ensembl - ENSDARG00000001769
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 PTPRAENSGALG00000015995Gallus gallus
 PTPRAENSG00000132670Homo sapiens
 PtpraENSMUSG00000027303Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
ptprea / protein tyrosine phosphatase, receptor type, E, a / PTPRE* / P49446* / P23469* / protein tyrosine phosphatase, receptor type E* / Receptor-type tyrosine-protein phosphatase epsilon *ENSDARG0000001589153
ptpreb / protein tyrosine phosphatase, receptor type, E, b / PTPRE* / P49446* / P23469* / protein tyrosine phosphatase, receptor type E* / Receptor-type tyrosine-protein phosphatase epsilon *ENSDARG0000002115152
ptprfb / A4IFW2 / protein tyrosine phosphatase, receptor type, f, b / PTPRF* / P10586* / A2A8L5* / Receptor-type tyrosine-protein phosphatase F * / protein tyrosine phosphatase, receptor type F*ENSDARG0000000575439
ptprsa / protein tyrosine phosphatase, receptor type, s, a / PTPRS* / B0V2N1* / Q13332* / Receptor-type tyrosine-protein phosphatase S * / protein tyrosine phosphatase, receptor type S*ENSDARG0000005973839
ptprfa / protein tyrosine phosphatase, receptor type, f, a / PTPRF* / A2A8L5* / P10586* / protein tyrosine phosphatase, receptor type F* / Receptor-type tyrosine-protein phosphatase F *ENSDARG0000010347939
ptprsa / protein tyrosine phosphatase, receptor type, s, a / PTPRS* / Q13332* / protein tyrosine phosphatase, receptor type S*ENSDARG0000011094035
ptprk / protein tyrosine phosphatase, receptor type, K / P35822* / Q15262*ENSDARG0000006341629
ptprc / protein tyrosine phosphatase, receptor type, CENSDARG0000007143729
ptprt / protein tyrosine phosphatase, receptor type, t / O14522* / Q99M80* / Receptor-type tyrosine-protein phosphatase T *ENSDARG0000007478128
ptprga / protein tyrosine phosphatase, receptor type, g a / PTPRG* / P23470* / protein tyrosine phosphatase, receptor type G*ENSDARG0000004500627
ptprz1a / protein tyrosine phosphatase, receptor-type, Z polypeptide 1a / B9EKR1* / P23471* / PTPRZ1* / protein tyrosine phosphatase, receptor type Z1* / protein tyrosine phosphatase, recep...ENSDARG0000005181427
ca16b / carbonic anhydrase XVI b / PTPRG* / P23470* / protein tyrosine phosphatase, receptor type G* / receptor-type tyrosine-protein phosphatase gamma isoform 2 *ENSDARG0000006012327
ptprt / protein tyrosine phosphatase, receptor type, t / O14522*ENSDARG0000009757227
ptprub / protein tyrosine phosphatase, receptor type, U, b / PTPRU* / B1AUH1* / Q92729* / protein tyrosine phosphatase, receptor type U*ENSDARG0000010108127
ptprz1b / protein tyrosine phosphatase, receptor-type, Z polypeptide 1b / B9EKR1* / P23471* / PTPRZ1* / protein tyrosine phosphatase, receptor type Z1* / protein tyrosine phosphatase, recep...ENSDARG0000002087126
ptprua / protein tyrosine phosphatase, receptor type, U, a / PTPRU* / B1AUH1* / Q92729* / protein tyrosine phosphatase, receptor type U*ENSDARG0000009263826
si:ch1073-391i24.1 / PTPRM* / P28827* / P28828* / protein tyrosine phosphatase, receptor type M*ENSDARG0000008917212
CABZ01084131.1 / PTPRM* / P28827* / protein tyrosine phosphatase, receptor type M*ENSDARG0000011476212


Protein motifs (from Interpro)
Interpro ID Name
 IPR000242  PTP type protein phosphatase
 IPR000387  Tyrosine specific protein phosphatases domain
 IPR003595  Protein-tyrosine phosphatase, catalytic
 IPR016130  Protein-tyrosine phosphatase, active site
 IPR016336  Receptor tyrosine-protein phosphatase, alpha/epsilon-type
 IPR027262  Receptor tyrosine-protein phosphatase alpha
 IPR029021  Protein-tyrosine phosphatase-like


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006470 protein dephosphorylation IEA
 biological_processGO:0016311 dephosphorylation IEA
 biological_processGO:0035335 peptidyl-tyrosine dephosphorylation IEA
 biological_processGO:0045859 regulation of protein kinase activity IDA
 biological_processGO:0060027 convergent extension involved in gastrulation IMP
 biological_processGO:0060041 retina development in camera-type eye IMP
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0004721 phosphoprotein phosphatase activity IEA
 molecular_functionGO:0004725 protein tyrosine phosphatase activity IEA
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0016791 phosphatase activity IEA


Pathways (from Reactome)
Pathway description
NCAM signaling for neurite out-growth
RAF/MAP kinase cascade


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000046 retinal neural layer retinal neural layer hypoplastic , abnormal
Show

 ZFA:0000054 pericardium pericardium edematous , abnormal
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 ZFA:0000084 yolk yolk edematous , abnormal
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 ZFA:0000106 extension extension decreased length , abnormal
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 ZFA:0000107 eye eye decreased size , abnormal
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 ZFA:0000152 retina retina cell decreased amount , abnormal
retina disorganized , abnormal
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 ZFA:0000435 cranial nerve II cranial nerve II defasciculated , abnormal
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 ZFA:0001094 whole organism whole organism decreased length , abnormal
whole organism dead , abnormal
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Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000025319 fynb / F1RDG9 / FYN proto-oncogene, Src family tyrosine kinase b / FYN* / P39688* / P06241* / Tyrosine-protein kinase Fyn * / FYN proto-oncogene, Src family tyrosine kinase*  / complex
 ENSDARG00000038059 grb2b / growth factor receptor-bound protein 2b / GRB2* / Q60631* / P62993* / growth factor receptor bound protein 2*  / reaction / complex
 ENSDARG00000019231 sptan1 / spectrin alpha, non-erythrocytic 1 / SPTA1* / Q13813* / P08032* / P16546* / P02549* / spectrin alpha, erythrocytic 1* / Spectrin alpha chain, erythrocytic 1 * / Spectrin alpha chai...  / complex
 ENSDARG00000011370 fyna / Q6EWH2 / FYN proto-oncogene, Src family tyrosine kinase a / FYN* / P06241* / P39688* / Tyrosine-protein kinase Fyn * / FYN proto-oncogene, Src family tyrosine kinase*  / complex
 ENSDARG00000105276 grb2a / growth factor receptor-bound protein 2a / GRB2* / Q60631* / P62993* / growth factor receptor bound protein 2*  / reaction / complex






 

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