ENSDARG00000006568


Danio rerio
potassiumkcnmb2channelioncalcium-activatedtransportmembraneactivitybkbetasubunitkcnmbballchaindomaindetectioncalciumchemicalsynaptictransmissionregulationmolecularfunctiontransmembranevoltage-gatedcomplexintegralcomponentregulatorcaactivated

Features
Gene ID: ENSDARG00000006568
  
Biological name :kcnmb2
  
Synonyms : kcnmb2 / potassium large conductance calcium-activated channel, subfamily M, beta member 2
  
Possible biological names infered from orthology : AC117457.1 / Calcium-activated potassium channel subunit beta-2 / KCNMB1 / potassium calcium-activated channel subfamily M regulatory beta subunit 1 / potassium calcium-activated channel subfamily M regulatory beta subunit 2 / Q16558 / Q9CZM9 / Q9Y691
  
Species: Danio rerio
  
Chr. number: 2
Strand: 1
Band:
Gene start: 7818368
Gene end: 7829400
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000015616
NCBI entrez gene - 541398     See in Manteia.
RefSeq - NM_001013525
RefSeq Peptide - NP_001013543
swissprot - A5WVU1
ZFIN ID - ZDB-GENE-050320-97
Ensembl - ENSDARG00000006568
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ENSGALG00000031929Gallus gallus
 KCNMB1ENSGALG00000002118Gallus gallus
 AC117457.1ENSG00000275163Homo sapiens
 KCNMB1ENSG00000145936Homo sapiens
 KCNMB2ENSG00000197584Homo sapiens
 Kcnmb1ENSMUSG00000020155Mus musculus
 Kcnmb2ENSMUSG00000037610Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
si:ch211-247n2.1 / KCNMB2* / Q9Y691* / Q9CZM9* / KCNMB1* / Q16558* / AC117457.1* / Calcium-activated potassium channel subunit beta-2 * / potassium calcium-activated channel subfamily M reg...ENSDARG0000000171256
si:ch211-38m6.7 / KCNMB3* / Q9NPA1* / potassium calcium-activated channel subfamily M regulatory beta subunit 3*ENSDARG0000006312928


Protein motifs (from Interpro)
Interpro ID Name
 IPR003930  Potassium channel, calcium-activated, BK, beta subunit
 IPR015382  KCNMB2, ball/chain domain


Gene Ontology (GO)
response to chemicaldetection of stimulusestablishment of localizationcell communicationregulation of molecular functionresponse to chemicaldetection of stimulusestablishment of localizationcell communicationregulation of molecular functionresponse to chemicaldetection of stimulusestablishment of localizationcell communicationregulation of molecular functionresponse to chemicaldetection of stimulusestablishment of localizationcell communicationregulation of molecular functionresponse to chemicaldetection of stimulusestablishment of localizationcell communicationregulation of molecular functionresponse to chemicaldetection of stimulusestablishment of localizationcell communicationregulation of molecular functionresponse to chemicaldetection of stimulusestablishment of localizationcell communicationregulation of molecular functionresponse to chemicaldetection of stimulusestablishment of localizationcell communicationregulation of molecular functionresponse to chemicaldetection of stimulusestablishment of localizationcell communicationregulation of molecular functionresponse to chemicaldetection of stimulusestablishment of localizationcell communicationregulation of molecular functionresponse to chemicalresponse to chemicaldetection of stimulusdetection of stimulusestablishment of localizatioestablishment of localizationcell communicationcell communicationregulation of molecular funcregulation of molecular function
transmembrane transporter activitychannel regulator activitytransmembrane transporter activitychannel regulator activitytransmembrane transporter activitychannel regulator activitytransmembrane transporter activitychannel regulator activitytransmembrane transporter activitychannel regulator activitytransmembrane transporter activitychannel regulator activitytransmembrane transporter activitychannel regulator activitytransmembrane transporter activitychannel regulator activitytransmembrane transporter activitychannel regulator activitytransmembrane transporter activitychannel regulator activitytransmembrane transporter activitytransmembrane transporter activitychannel regulator activitychannel regulator activity
cellmembraneprotein-containing complexcellmembraneprotein-containing complexcellmembraneprotein-containing complexcellmembraneprotein-containing complexcellmembraneprotein-containing complexcellmembraneprotein-containing complexcellmembraneprotein-containing complexcellmembraneprotein-containing complexcellmembraneprotein-containing complexcellmembraneprotein-containing complexcellcellmembranemembraneprotein-containing complexprotein-containing complex
TypeGO IDTermEv.Code
 biological_processGO:0005513 detection of calcium ion IBA
 biological_processGO:0006813 potassium ion transport IEA
 biological_processGO:0007268 chemical synaptic transmission IBA
 biological_processGO:0065009 regulation of molecular function IEA
 biological_processGO:0071805 potassium ion transmembrane transport IBA
 cellular_componentGO:0008076 voltage-gated potassium channel complex IBA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0015269 calcium-activated potassium channel activity IBA
 molecular_functionGO:0015459 potassium channel regulator activity IBA


Pathways (from Reactome)
Pathway description
Ca2+ activated K+ channels


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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