ENSDARG00000006602
Danio rerio membrane activity chrna2a receptor neurotransmitter-gated ion-channel ion channel nicotinic transport domain synaptic transmission potential acetylcholine-gated cell highly calcium permeable receptors ligand-binding conserved site signal transduction cholinergic neuromuscular response
Features Gene ID: ENSDARG00000006602 Biological name :chrna2a Synonyms : cholinergic receptor, nicotinic, alpha 2a (neuronal) / Possible biological names infered from orthology : cholinergic receptor nicotinic alpha 2 subunit / / / / Species: Danio rerio Chr. number: 17 Strand: 1 Band: Gene start: 6079881 Gene end: 6101820 Corresponding Affymetrix probe sets: Dr.26447.1.S1_at (Zebrafish Array) NM_001040327_at (Zebrafish Genome Array with custom cdf files) Cross references: Ensembl peptide - ENSDARP00000028704678575
See in Manteia .
NM_001040327 NP_001035417 Q1RLX8 ZDB-GENE-040108-2 ENSDARG00000006602
See expression report in BioGPS See gene description in Wikigenes See co-cited genes in PubMed Ortholog prediction (from Ensembl )Paralog prediction (from Ensembl ) chrna2b / cholinergic receptor, nicotinic, alpha 2b (neuronal) / CHRNA2* / Q15822* / Q91X60* / cholinergic receptor nicotinic alpha 2 subunit* / cholinergic receptor, nicotinic, alpha polyp... ENSDARG00000057025 77 chrna4b / cholinergic receptor, nicotinic, alpha 4b / CHRNA4* / O70174* / P43681* / cholinergic receptor nicotinic alpha 4 subunit* / cholinergic receptor, nicotinic, alpha polypeptide 4* ENSDARG00000070724 67 chrna4a / cholinergic receptor, nicotinic, alpha 4a / CHRNA4* / O70174* / P43681* / cholinergic receptor nicotinic alpha 4 subunit* / cholinergic receptor, nicotinic, alpha polypeptide 4* ENSDARG00000087071 57 chrna6 / cholinergic receptor, nicotinic, alpha 6 / Q15825* / Q9R0W9* / cholinergic receptor nicotinic alpha 6 subunit* / cholinergic receptor, nicotinic, alpha polypeptide 6* ENSDARG00000055559 53 chrna3 / cholinergic receptor, nicotinic, alpha 3 / P32297* / cholinergic receptor nicotinic alpha 3 subunit* / cholinergic receptor, nicotinic, alpha polypeptide 3* ENSDARG00000100991 52 chrna5 / cholinergic receptor, nicotinic, alpha 5 / P30532* / Q2MKA5* / cholinergic receptor nicotinic alpha 5 subunit* / cholinergic receptor, nicotinic, alpha polypeptide 5* ENSDARG00000003420 46 chrnb3a / cholinergic receptor, nicotinic, beta polypeptide 3a / Q8BMN3* / CHRNB3* / Q05901* / cholinergic receptor nicotinic beta 3 subunit* / cholinergic receptor, nicotinic, beta polypeptide 3* ENSDARG00000052764 46 chrnb2b / cholinergic receptor, nicotinic, beta 2b / CHRNB2* / P17787* / Q9ERK7* / cholinergic receptor nicotinic beta 2 subunit* / cholinergic receptor, nicotinic, beta polypeptide 2 (neuronal)* ENSDARG00000017790 45 chrnb3b / cholinergic receptor, nicotinic, beta 3b (neuronal) / CHRNB3* / Q05901* / Q8BMN3* / cholinergic receptor nicotinic beta 3 subunit* / cholinergic receptor, nicotinic, beta polypeptide 3* ENSDARG00000038508 45 chrnb4 / cholinergic receptor, nicotinic, beta 4 (neuronal) / P30926* / Q8R493* / cholinergic receptor nicotinic beta 4 subunit* / cholinergic receptor, nicotinic, beta polypeptide 4* ENSDARG00000101677 45 chrnb2a / cholinergic receptor, nicotinic, beta 2a ENSDARG00000115778 44 Q98880 / chrna1 / cholinergic receptor, nicotinic, alpha 1 (muscle) / P02708* / P04756* / cholinergic receptor nicotinic alpha 1 subunit* / cholinergic receptor, nicotinic, alpha polypeptid... ENSDARG00000009021 41 chrnb2l / cholinergic receptor, nicotinic, beta 2, like ENSDARG00000021392 40
Protein motifs (from Interpro ) IPR002394 Nicotinic acetylcholine receptor IPR006029 Neurotransmitter-gated ion-channel transmembrane domain IPR006201 Neurotransmitter-gated ion-channel IPR006202 Neurotransmitter-gated ion-channel ligand-binding domain IPR018000 Neurotransmitter-gated ion-channel, conserved site
Gene Ontology (GO ) establishment of localization cell communication cellular response to stimulus response to chemical regulation of biological quality system process establishment of localization cell communication cellular response to stimulus response to chemical regulation of biological quality system process establishment of localization cell communication cellular response to stimulus response to chemical regulation of biological quality system process establishment of localization cell communication cellular response to stimulus response to chemical regulation of biological quality system process establishment of localization cell communication cellular response to stimulus response to chemical regulation of biological quality system process establishment of localization cell communication cellular response to stimulus response to chemical regulation of biological quality system process establishment of localization cell communication cellular response to stimulus response to chemical regulation of biological quality system process establishment of localization cell communication cellular response to stimulus response to chemical regulation of biological quality system process establishment of localization cell communication cellular response to stimulus response to chemical regulation of biological quality system process establishment of localization cell communication cellular response to stimulus response to chemical regulation of biological quality system process establishment of localiestablishment of localization cell communicationcell communication cellular response to stcellular response to stimulus response to chemicalresponse to chemical regulation of biologicaregulation of biological quality system processsystem process signaling receptor activity transmembrane transporter activity ion binding neurotransmitter binding hormone binding drug binding signaling receptor activity transmembrane transporter activity ion binding neurotransmitter binding hormone binding drug binding signaling receptor activity transmembrane transporter activity ion binding neurotransmitter binding hormone binding drug binding signaling receptor activity transmembrane transporter activity ion binding neurotransmitter binding hormone binding drug binding signaling receptor activity transmembrane transporter activity ion binding neurotransmitter binding hormone binding drug binding signaling receptor activity transmembrane transporter activity ion binding neurotransmitter binding hormone binding drug binding signaling receptor activity transmembrane transporter activity ion binding neurotransmitter binding hormone binding drug binding signaling receptor activity transmembrane transporter activity ion binding neurotransmitter binding hormone binding drug binding signaling receptor activity transmembrane transporter activity ion binding neurotransmitter binding hormone binding drug binding signaling receptor activity transmembrane transporter activity ion binding neurotransmitter binding hormone binding drug binding signaling receptor actisignaling receptor activity transmembrane transporttransmembrane transporter activity ion bindingion binding neurotransmitter bindinneurotransmitter binding hormone bindinghormone binding drug bindingdrug binding cell membrane protein-containing complex cell junction synapse cell membrane protein-containing complex cell junction synapse cell membrane protein-containing complex cell junction synapse cell membrane protein-containing complex cell junction synapse cell membrane protein-containing complex cell junction synapse cell membrane protein-containing complex cell junction synapse cell membrane protein-containing complex cell junction synapse cell membrane protein-containing complex cell junction synapse cell membrane protein-containing complex cell junction synapse cell membrane protein-containing complex cell junction synapse cellcell membranemembrane protein-containing complexprotein-containing complex cell junctioncell junction synapsesynapse
Pathways (from Reactome )Phenotype (from MGI , Zfin or HPO ) ZFA:0009125 olfactory receptor cell olfactory receptor cell absent , abnormal
Show ZFA:0009150 Rohon-Beard neuron Rohon-Beard neuron absent , abnormal
Show
Interacting proteins (from Reactome ) ENSDARG00000006602 chrna2a / cholinergic receptor, nicotinic, alpha 2a (neuronal) / CHRNA2* / Q15822* / Q91X60* / cholinergic receptor nicotinic alpha 2 subunit* / cholinergic receptor, nicotinic, alpha polyp... / complex ENSDARG00000057025 chrna2b / cholinergic receptor, nicotinic, alpha 2b (neuronal) / CHRNA2* / Q15822* / Q91X60* / cholinergic receptor nicotinic alpha 2 subunit* / cholinergic receptor, nicotinic, alpha polyp... / complex ENSDARG00000038508 chrnb3b / cholinergic receptor, nicotinic, beta 3b (neuronal) / CHRNB3* / Q05901* / Q8BMN3* / cholinergic receptor nicotinic beta 3 subunit* / cholinergic receptor, nicotinic, beta polypeptide 3* / complex
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