ENSDARG00000006609
Danio rerio protein map2k2a kinase activation activity binding phosphorylation regulation mapk domain serine site atp signal transduction threonine-protein active kinase-like superfamily mitotic cell cycle stress-activated signaling cascade apoptotic process cytoplasm nucleotide threonine erk
Features Gene ID: ENSDARG00000006609 Biological name :map2k2a Synonyms : map2k2a / mitogen-activated protein kinase kinase 2a Possible biological names infered from orthology : AC011005.1 / MAP2K2 / mitogen-activated protein kinase kinase 2 / Mus musculus mitogen-activated protein kinase kinase 2 (Map2k2), transcript variant 2, mRNA. / P36507 / Q63932 Species: Danio rerio Chr. number: 22 Strand: -1 Band: Gene start: 20388621 Gene end: 20403194 Corresponding Affymetrix probe sets: Dr.8.3.A1_at (Zebrafish Array) Cross references: Ensembl peptide - ENSDARP00000014914 NCBI entrez gene - 563181
See in Manteia .
swissprot - Q1LY62 ZFIN ID - ZDB-GENE-041027-1 Ensembl - ENSDARG00000006609
See expression report in BioGPS See gene description in Wikigenes See co-cited genes in PubMed Ortholog prediction (from Ensembl )
Paralog prediction (from Ensembl ) map2k2b / mitogen-activated protein kinase kinase 2b / P36507* / MAP2K2* / Q63932* / AC011005.1* / mitogen-activated protein kinase kinase 2* / Mus musculus mitogen-activated protein kinase... ENSDARG00000068918 87 map2k1 / mitogen-activated protein kinase kinase 1 / P31938* / Q02750* / Dual specificity mitogen-activated protein kinase kinase 1 * ENSDARG00000007825 77 map2k5 / mitogen-activated protein kinase kinase 5 / Q13163* / Q9WVS7* / Dual specificity mitogen-activated protein kinase kinase 5 * ENSDARG00000011851 36 map2k7 / mitogen-activated protein kinase kinase 7 / O14733* / Q8CE90* / Dual specificity mitogen-activated protein kinase kinase 7 * ENSDARG00000008279 32 map2k4a / mitogen-activated protein kinase kinase 4a / P45985* / MAP2K4* / P47809* / mitogen-activated protein kinase kinase 4* / Dual specificity mitogen-activated protein kinase kinase 4 * ENSDARG00000063583 32 map2k4b / mitogen-activated protein kinase kinase 4b / P45985* / MAP2K4* / P47809* / mitogen-activated protein kinase kinase 4* / Dual specificity mitogen-activated protein kinase kinase 4 * ENSDARG00000077177 32 map2k6 / Q9DGE0 / mitogen-activated protein kinase kinase 6 / P52564* ENSDARG00000099184 30
Protein motifs (from Interpro )
Gene Ontology (GO ) nitrogen compound metabolic process cellular metabolic process primary metabolic process organic substance metabolic process cell cycle cell communication cellular response to stimulus response to stress regulation of molecular function cell death nitrogen compound metabolic process cellular metabolic process primary metabolic process organic substance metabolic process cell cycle cell communication cellular response to stimulus response to stress regulation of molecular function cell death nitrogen compound metabolic process cellular metabolic process primary metabolic process organic substance metabolic process cell cycle cell communication cellular response to stimulus response to stress regulation of molecular function cell death nitrogen compound metabolic process cellular metabolic process primary metabolic process organic substance metabolic process cell cycle cell communication cellular response to stimulus response to stress regulation of molecular function cell death nitrogen compound metabolic process cellular metabolic process primary metabolic process organic substance metabolic process cell cycle cell communication cellular response to stimulus response to stress regulation of molecular function cell death nitrogen compound metabolic process cellular metabolic process primary metabolic process organic substance metabolic process cell cycle cell communication cellular response to stimulus response to stress regulation of molecular function cell death nitrogen compound metabolic process cellular metabolic process primary metabolic process organic substance metabolic process cell cycle cell communication cellular response to stimulus response to stress regulation of molecular function cell death nitrogen compound metabolic process cellular metabolic process primary metabolic process organic substance metabolic process cell cycle cell communication cellular response to stimulus response to stress regulation of molecular function cell death nitrogen compound metabolic process cellular metabolic process primary metabolic process organic substance metabolic process cell cycle cell communication cellular response to stimulus response to stress regulation of molecular function cell death nitrogen compound metabolic process cellular metabolic process primary metabolic process organic substance metabolic process cell cycle cell communication cellular response to stimulus response to stress regulation of molecular function cell death nitrogen componitrogen compound metabolic process cellular metabcellular metabolic process primary metaboprimary metabolic process organic substaorganic substance metabolic process cell cyclecell cycle cell communicacell communication cellular respocellular response to stimulus response to stresponse to stress regulation of regulation of molecular function cell deathcell death organic cyclic compound binding heterocyclic compound binding small molecule binding catalytic activity, acting on a protein transferase activity ion binding carbohydrate derivative binding drug binding organic cyclic compound binding heterocyclic compound binding small molecule binding catalytic activity, acting on a protein transferase activity ion binding carbohydrate derivative binding drug binding organic cyclic compound binding heterocyclic compound binding small molecule binding catalytic activity, acting on a protein transferase activity ion binding carbohydrate derivative binding drug binding organic cyclic compound binding heterocyclic compound binding small molecule binding catalytic activity, acting on a protein transferase activity ion binding carbohydrate derivative binding drug binding organic cyclic compound binding heterocyclic compound binding small molecule binding catalytic activity, acting on a protein transferase activity ion binding carbohydrate derivative binding drug binding organic cyclic compound binding heterocyclic compound binding small molecule binding catalytic activity, acting on a protein transferase activity ion binding carbohydrate derivative binding drug binding organic cyclic compound binding heterocyclic compound binding small molecule binding catalytic activity, acting on a protein transferase activity ion binding carbohydrate derivative binding drug binding organic cyclic compound binding heterocyclic compound binding small molecule binding catalytic activity, acting on a protein transferase activity ion binding carbohydrate derivative binding drug binding organic cyclic compound binding heterocyclic compound binding small molecule binding catalytic activity, acting on a protein transferase activity ion binding carbohydrate derivative binding drug binding organic cyclic compound binding heterocyclic compound binding small molecule binding catalytic activity, acting on a protein transferase activity ion binding carbohydrate derivative binding drug binding organic cyclic coorganic cyclic compound binding heterocyclic compheterocyclic compound binding small molecule bismall molecule binding catalytic activitcatalytic activity, acting on a protein transferase activtransferase activity ion bindingion binding carbohydrate dericarbohydrate derivative binding drug bindingdrug binding cell cell cell cell cell cell cell cell cell cell cellcell
Pathways (from Reactome )
Phenotype (from MGI , Zfin or HPO )
No match
Interacting proteins (from Reactome ) ENSDARG00000006609 map2k2a / mitogen-activated protein kinase kinase 2a / P36507* / MAP2K2* / Q63932* / AC011005.1* / mitogen-activated protein kinase kinase 2* / Mus musculus mitogen-activated protein kinase... / complex ENSDARG00000017661 braf / B-Raf proto-oncogene, serine/threonine kinase / P15056* / P28028* / Serine/threonine-protein kinase B-raf * / complex / reaction ENSDARG00000026630 mark3b / MAP/microtubule affinity-regulating kinase 3b / MARK1* / MARK3* / P27448* / Q9P0L2* / Q8VHJ5* / Q03141* / Serine/threonine-protein kinase MARK1 * / microtubule affinity regulating ... / complex / reaction ENSDARG00000027552 mapk1 / mitogen-activated protein kinase 1 / P28482* / P63085* / Mus musculus mitogen-activated protein kinase 1 (Mapk1), transcript variant 3, mRNA.* / complex / reaction ENSDARG00000039872 lamtor2 / late endosomal/lysosomal adaptor, MAPK and MTOR activator 2 / Q9JHS3* / Q9Y2Q5* / Ragulator complex protein LAMTOR2 * / complex / reaction ENSDARG00000070573 mapk3 / mitogen-activated protein kinase 3 / P27361* / Q63844* / complex / reaction ENSDARG00000057075 lamtor3 / late endosomal/lysosomal adaptor, MAPK and MTOR activator 3 / O88653* / Q9UHA4* / complex / reaction ENSDARG00000098359 il17rd / interleukin 17 receptor D / Q8NFM7* / complex / reaction ENSDARG00000005651 hrasb / -Ha-ras Harvey rat sarcoma viral oncogene homolog b / HRAS* / P01112* / Q61411* / HRas proto-oncogene, GTPase* / GTPase HRas GTPase HRas, N-terminally processed* / complex / reaction ENSDARG00000013078 ywhaba / Q5PRD0 / tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide a / YWHAB* / P31946* / tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activat... / complex / reaction ENSDARG00000038225 nras / NRAS proto-oncogene, GTPase / P01111* / neuroblastoma ras oncogene* / complex / reaction
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