ENSDARG00000008551


Danio rerio

Features
Gene ID: ENSDARG00000008551
  
Biological name :pole3
  
Synonyms : pole3 / polymerase (DNA directed), epsilon 3 (p17 subunit)
  
Possible biological names infered from orthology : DNA polymerase epsilon 3, accessory subunit / Q9NRF9
  
Species: Danio rerio
  
Chr. number: 5
Strand: -1
Band:
Gene start: 32888119
Gene end: 32890807
  
Corresponding Affymetrix probe sets: Dr.14292.1.S1_at (Zebrafish Array)   NM_200801_at (Zebrafish Genome Array with custom cdf files)   
  
Cross references: Ensembl peptide - ENSDARP00000002886
NCBI entrez gene - 393774     See in Manteia.
RefSeq - NM_200801
RefSeq Peptide - NP_957095
swissprot - Q6PBL4
ZFIN ID - ZDB-GENE-040426-1773
Ensembl - ENSDARG00000008551
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 POLE3ENSGALG00000008873Gallus gallus
 POLE3ENSG00000148229Homo sapiens
 Pole3ENSMUSG00000028394Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
nfyba / nuclear transcription factor Y, beta a / NFYB* / P25208* / P63139* / nuclear transcription factor Y subunit beta*ENSDARG0000003918526
nfybb / nuclear transcription factor Y, beta b / NFYB* / P25208* / P63139* / nuclear transcription factor Y subunit beta*ENSDARG0000004561126


Protein motifs (from Interpro)
Interpro ID Name
 IPR003958  Transcription factor CBF/NF-Y/archaeal histone domain
 IPR009072  Histone-fold


Gene Ontology (GO)
TypeGO IDTermEv.Code
 cellular_componentGO:0005634 nucleus IEA
 molecular_functionGO:0046982 protein heterodimerization activity IEA


Pathways (from Reactome)
Pathway description
Recognition of DNA damage by PCNA-containing replication complex
Telomere C-strand synthesis initiation
PCNA-Dependent Long Patch Base Excision Repair
Termination of translesion DNA synthesis
HDR through Homologous Recombination (HRR)
Gap-filling DNA repair synthesis and ligation in GG-NER
Dual Incision in GG-NER
Dual incision in TC-NER
Gap-filling DNA repair synthesis and ligation in TC-NER
DNA replication initiation
Activation of the pre-replicative complex


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000052721 prim2 / DNA primase subunit 2 / P33610* / P49643* / DNA primase large subunit *  / complex / reaction
 ENSDARG00000013016 pole4 / polymerase (DNA-directed), epsilon 4, accessory subunit / Q9CQ36* / Q9NR33* / DNA polymerase epsilon 4, accessory subunit* / polymerase (DNA-directed), epsilon 4 (p12 subunit)*  / complex
 ENSDARG00000015070 pola2 / polymerase (DNA directed), alpha 2 / P33611* / Q14181* / DNA polymerase alpha 2, accessory subunit*  / complex / reaction
 ENSDARG00000058533 pole / polymerase (DNA directed), epsilon / Q07864* / Q9WVF7* / DNA polymerase epsilon, catalytic subunit*  / complex
 ENSDARG00000045308 pola1 / polymerase (DNA directed), alpha 1 / P09884* / P33609* / DNA polymerase alpha 1, catalytic subunit*  / complex / reaction






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2025
contact: otassy@igbmc.fr