ENSDARG00000013016


Danio rerio

Features
Gene ID: ENSDARG00000013016
  
Biological name :pole4
  
Synonyms : pole4 / polymerase (DNA-directed), epsilon 4, accessory subunit
  
Possible biological names infered from orthology : DNA polymerase epsilon 4, accessory subunit / polymerase (DNA-directed), epsilon 4 (p12 subunit) / Q9CQ36 / Q9NR33
  
Species: Danio rerio
  
Chr. number: 11
Strand: -1
Band:
Gene start: 6197276
Gene end: 6206625
  
Corresponding Affymetrix probe sets: Dr.14836.1.A1_at (Zebrafish Array)   
  
Cross references: Ensembl peptide - ENSDARP00000119014
Ensembl peptide - ENSDARP00000016362
Ensembl peptide - ENSDARP00000124578
Ensembl peptide - ENSDARP00000125078
NCBI entrez gene - 553610     See in Manteia.
RefSeq - NM_001351798
RefSeq Peptide - NP_001338727
swissprot - F1RCI6
swissprot - E9QBW0
swissprot - F8W2X1
swissprot - F8W5J0
ZFIN ID - ZDB-GENE-050522-309
Ensembl - ENSDARG00000013016
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 POLE4ENSGALG00000031679Gallus gallus
 POLE4ENSG00000115350Homo sapiens
 Pole4ENSMUSG00000030042Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
nfyc / nuclear transcription factor Y, gamma / Q13952* / nuclear transcription factor Y subunit gamma*ENSDARG0000007015122


Protein motifs (from Interpro)
Interpro ID Name
 IPR003958  Transcription factor CBF/NF-Y/archaeal histone domain
 IPR009072  Histone-fold


Gene Ontology (GO)
TypeGO IDTermEv.Code
 cellular_componentGO:0005634 nucleus IEA
 molecular_functionGO:0046982 protein heterodimerization activity IEA


Pathways (from Reactome)
Pathway description
Recognition of DNA damage by PCNA-containing replication complex
Telomere C-strand synthesis initiation
PCNA-Dependent Long Patch Base Excision Repair
Termination of translesion DNA synthesis
HDR through Homologous Recombination (HRR)
Gap-filling DNA repair synthesis and ligation in GG-NER
Dual Incision in GG-NER
Dual incision in TC-NER
Gap-filling DNA repair synthesis and ligation in TC-NER
DNA replication initiation
Activation of the pre-replicative complex


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000052721 prim2 / DNA primase subunit 2 / P33610* / P49643* / DNA primase large subunit *  / complex / reaction
 ENSDARG00000008551 pole3 / polymerase (DNA directed), epsilon 3 (p17 subunit) / Q9NRF9* / DNA polymerase epsilon 3, accessory subunit*  / complex
 ENSDARG00000058533 pole / polymerase (DNA directed), epsilon / Q07864* / Q9WVF7* / DNA polymerase epsilon, catalytic subunit*  / complex
 ENSDARG00000015070 pola2 / polymerase (DNA directed), alpha 2 / P33611* / Q14181* / DNA polymerase alpha 2, accessory subunit*  / complex / reaction
 ENSDARG00000045308 pola1 / polymerase (DNA directed), alpha 1 / P09884* / P33609* / DNA polymerase alpha 1, catalytic subunit*  / complex / reaction






 

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