ENSDARG00000010477


Danio rerio

Features
Gene ID: ENSDARG00000010477
  
Biological name :p2rx3a
  
Synonyms : p2rx3a / purinergic receptor P2X, ligand-gated ion channel, 3a
  
Possible biological names infered from orthology : P2RX3 / P2X purinoceptor 3 / P56373 / purinergic receptor P2X 3 / Q3UR32
  
Species: Danio rerio
  
Chr. number: 14
Strand: -1
Band:
Gene start: 21942383
Gene end: 21959712
  
Corresponding Affymetrix probe sets: Dr.8239.1.S1_at (Zebrafish Array)   
  
Cross references: Ensembl peptide - ENSDARP00000019781
swissprot - B3DG55
ZFIN ID - ZDB-GENE-000427-3
Ensembl - ENSDARG00000010477
  
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 P2RX3ENSGALG00000040479Gallus gallus
 P2RX3ENSG00000109991Homo sapiens
 P2rx3ENSMUSG00000027071Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
p2rx3b / purinergic receptor P2X, ligand-gated ion channel, 3b / P2RX3* / Q3UR32* / P56373* / P2X purinoceptor 3 * / purinergic receptor P2X 3*ENSDARG0000002971859
p2rx5 / purinergic receptor P2X, ligand-gated ion channel, 5 / Q93086* / P2RX5-TAX1BP3* / purinergic receptor P2X 5* / P2RX5-TAX1BP3 readthrough (NMD candidate)*ENSDARG0000000445539
p2rx1 / purinergic receptor P2X, ligand-gated ion channel, 1 / P51575* / P51576* / P2X purinoceptor 1 * / purinergic receptor P2X 1*ENSDARG0000001669539
p2rx2 / purinergic receptor P2X, ligand-gated ion channel, 2 / Q9UBL9* / Q8K3P1* / P2X purinoceptor 2 * / purinergic receptor P2X 2*ENSDARG0000000230037
p2rx4b / purinergic receptor P2X, ligand-gated ion channel, 4b / P2RX4* / Q99571* / purinergic receptor P2X 4*ENSDARG0000004245237
p2rx4a / purinergic receptor P2X, ligand-gated ion channel, 4a / P2RX4* / Q99571* / purinergic receptor P2X 4*ENSDARG0000004475237
p2rx8 / purinergic receptor P2X, ligand-gated ion channel, 8 / P2RX5* / Q93086* / P2RX5-TAX1BP3* / purinergic receptor P2X 5* / P2RX5-TAX1BP3 readthrough (NMD candidate)* / purinergic recep...ENSDARG0000002413933
p2rx7 / purinergic receptor P2X, ligand-gated ion channel, 7 / Q9Z1M0* / Q99572* / P2X purinoceptor 7 * / purinergic receptor P2X 7*ENSDARG0000004244032


Protein motifs (from Interpro)
Interpro ID Name
 IPR001429  P2X purinoreceptor
 IPR003046  P2X3 purinoceptor
 IPR027309  P2X purinoreceptor extracellular domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006811 ion transport IEA
 biological_processGO:0006812 cation transport IGI
 biological_processGO:0022008 neurogenesis IMP
 biological_processGO:0033198 response to ATP IEA
 biological_processGO:0035590 purinergic nucleotide receptor signaling pathway IEA
 biological_processGO:0051291 protein heterooligomerization IGI
 biological_processGO:0060079 excitatory postsynaptic potential IEA
 biological_processGO:0098655 cation transmembrane transport IEA
 cellular_componentGO:0005639 integral component of nuclear inner membrane IBA
 cellular_componentGO:0005887 integral component of plasma membrane IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane ISS
 cellular_componentGO:0098794 postsynapse IEA
 molecular_functionGO:0001614 purinergic nucleotide receptor activity IBA
 molecular_functionGO:0004931 extracellularly ATP-gated cation channel activity IGI
 molecular_functionGO:0005216 ion channel activity IEA
 molecular_functionGO:0005524 ATP binding IEA


Pathways (from Reactome)
Pathway description
Elevation of cytosolic Ca2+ levels
Platelet homeostasis


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000295 trigeminal ganglion trigeminal ganglion malformed , abnormal
Show

 ZFA:0001273 ventral mandibular arch ventral mandibular arch malformed , abnormal
Show

 ZFA:0001306 pharyngeal arch pharyngeal arch malformed , abnormal
Show

 ZFA:0001400 ceratohyal cartilage ceratohyal cartilage malformed , abnormal
Show

 ZFA:0001516 ceratobranchial cartilage ceratobranchial cartilage hypotrophic , abnormal
Show

 ZFA:0001555 epibranchial ganglion epibranchial ganglion malformed , abnormal
Show

 ZFA:0001611 pharyngeal arch 2 pharyngeal arch 2 morphology , abnormal
Show

 ZFA:0001612 pharyngeal arch 1 pharyngeal arch 1 morphology , abnormal
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2025
contact: otassy@igbmc.fr