ENSDARG00000024139


Danio rerio

Features
Gene ID: ENSDARG00000024139
  
Biological name :p2rx8
  
Synonyms : p2rx8 / purinergic receptor P2X, ligand-gated ion channel, 8
  
Possible biological names infered from orthology : P2RX5 / P2RX5-TAX1BP3 / P2RX5-TAX1BP3 readthrough (NMD candidate) / purinergic receptor P2X 5 / purinergic receptor P2X, ligand-gated ion channel, 5 / Q93086
  
Species: Danio rerio
  
Chr. number: 15
Strand: 1
Band:
Gene start: 16343073
Gene end: 16371103
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000038849
NCBI entrez gene - 387299     See in Manteia.
RefSeq - NM_198985
RefSeq Peptide - NP_945336
swissprot - F1QVA3
ZFIN ID - ZDB-GENE-030319-7
Ensembl - ENSDARG00000024139
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 P2RX5ENSGALG00000004613Gallus gallus
 P2RX5ENSG00000083454Homo sapiens
 P2RX5-TAX1BP3ENSG00000257950Homo sapiens
 P2rx5ENSMUSG00000005950Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
p2rx5 / purinergic receptor P2X, ligand-gated ion channel, 5 / Q93086* / P2RX5-TAX1BP3* / purinergic receptor P2X 5* / P2RX5-TAX1BP3 readthrough (NMD candidate)*ENSDARG0000000445550
p2rx4a / purinergic receptor P2X, ligand-gated ion channel, 4a / P2RX4* / Q99571* / purinergic receptor P2X 4*ENSDARG0000004475239
p2rx3b / purinergic receptor P2X, ligand-gated ion channel, 3b / P2RX3* / Q3UR32* / P56373* / P2X purinoceptor 3 * / purinergic receptor P2X 3*ENSDARG0000002971838
p2rx4b / purinergic receptor P2X, ligand-gated ion channel, 4b / P2RX4* / Q99571* / purinergic receptor P2X 4*ENSDARG0000004245237
p2rx1 / purinergic receptor P2X, ligand-gated ion channel, 1 / P51575* / P51576* / P2X purinoceptor 1 * / purinergic receptor P2X 1*ENSDARG0000001669536
p2rx2 / purinergic receptor P2X, ligand-gated ion channel, 2 / Q9UBL9* / Q8K3P1* / P2X purinoceptor 2 * / purinergic receptor P2X 2*ENSDARG0000000230035
p2rx3a / purinergic receptor P2X, ligand-gated ion channel, 3a / P2RX3* / Q3UR32* / P56373* / P2X purinoceptor 3 * / purinergic receptor P2X 3*ENSDARG0000001047734
p2rx7 / purinergic receptor P2X, ligand-gated ion channel, 7 / Q9Z1M0* / Q99572* / P2X purinoceptor 7 * / purinergic receptor P2X 7*ENSDARG0000004244034


Protein motifs (from Interpro)
Interpro ID Name
 IPR001429  P2X purinoreceptor
 IPR003048  P2X5 purinoceptor
 IPR027309  P2X purinoreceptor extracellular domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006811 ion transport IEA
 biological_processGO:0006812 cation transport IDA
 biological_processGO:0033198 response to ATP IEA
 biological_processGO:0035590 purinergic nucleotide receptor signaling pathway IEA
 biological_processGO:0060079 excitatory postsynaptic potential IEA
 biological_processGO:0098655 cation transmembrane transport IEA
 cellular_componentGO:0005639 integral component of nuclear inner membrane IBA
 cellular_componentGO:0005887 integral component of plasma membrane IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0098794 postsynapse IEA
 molecular_functionGO:0001614 purinergic nucleotide receptor activity IBA
 molecular_functionGO:0004931 extracellularly ATP-gated cation channel activity IDA
 molecular_functionGO:0005216 ion channel activity IEA
 molecular_functionGO:0005524 ATP binding IEA


Pathways (from Reactome)
Pathway description
Elevation of cytosolic Ca2+ levels
Platelet homeostasis


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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