ENSDARG00000042440


Danio rerio

Features
Gene ID: ENSDARG00000042440
  
Biological name :p2rx7
  
Synonyms : p2rx7 / purinergic receptor P2X, ligand-gated ion channel, 7
  
Possible biological names infered from orthology : P2X purinoceptor 7 / purinergic receptor P2X 7 / Q99572 / Q9Z1M0
  
Species: Danio rerio
  
Chr. number: 8
Strand: -1
Band:
Gene start: 30758169
Gene end: 30779101
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000062228
NCBI entrez gene - 387298     See in Manteia.
RefSeq - NM_198984
RefSeq Peptide - NP_945335
swissprot - F1QJ17
ZFIN ID - ZDB-GENE-030319-6
Ensembl - ENSDARG00000042440
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 P2RX7ENSGALG00000003863Gallus gallus
 P2RX7ENSG00000089041Homo sapiens
 P2rx7ENSMUSG00000029468Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
p2rx4a / purinergic receptor P2X, ligand-gated ion channel, 4a / P2RX4* / Q99571* / purinergic receptor P2X 4*ENSDARG0000004475230
p2rx4b / purinergic receptor P2X, ligand-gated ion channel, 4b / P2RX4* / Q99571* / purinergic receptor P2X 4*ENSDARG0000004245228
p2rx5 / purinergic receptor P2X, ligand-gated ion channel, 5 / Q93086* / P2RX5-TAX1BP3* / purinergic receptor P2X 5* / P2RX5-TAX1BP3 readthrough (NMD candidate)*ENSDARG0000000445526
p2rx2 / purinergic receptor P2X, ligand-gated ion channel, 2 / Q9UBL9* / Q8K3P1* / P2X purinoceptor 2 * / purinergic receptor P2X 2*ENSDARG0000000230025
p2rx3b / purinergic receptor P2X, ligand-gated ion channel, 3b / P2RX3* / Q3UR32* / P56373* / P2X purinoceptor 3 * / purinergic receptor P2X 3*ENSDARG0000002971824
p2rx1 / purinergic receptor P2X, ligand-gated ion channel, 1 / P51575* / P51576* / P2X purinoceptor 1 * / purinergic receptor P2X 1*ENSDARG0000001669523
p2rx3a / purinergic receptor P2X, ligand-gated ion channel, 3a / P2RX3* / Q3UR32* / P56373* / P2X purinoceptor 3 * / purinergic receptor P2X 3*ENSDARG0000001047722
p2rx8 / purinergic receptor P2X, ligand-gated ion channel, 8 / P2RX5* / Q93086* / P2RX5-TAX1BP3* / purinergic receptor P2X 5* / P2RX5-TAX1BP3 readthrough (NMD candidate)* / purinergic recep...ENSDARG0000002413922


Protein motifs (from Interpro)
Interpro ID Name
 IPR001429  P2X purinoreceptor
 IPR003050  P2X7 purinoceptor
 IPR027309  P2X purinoreceptor extracellular domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006811 ion transport IEA
 biological_processGO:0006812 cation transport IDA
 biological_processGO:0033198 response to ATP IEA
 biological_processGO:0035590 purinergic nucleotide receptor signaling pathway IEA
 biological_processGO:0048246 macrophage chemotaxis IMP
 biological_processGO:0060079 excitatory postsynaptic potential IEA
 biological_processGO:0098655 cation transmembrane transport IEA
 biological_processGO:0098703 calcium ion import across plasma membrane IDA
 cellular_componentGO:0005639 integral component of nuclear inner membrane IBA
 cellular_componentGO:0005886 plasma membrane IDA
 cellular_componentGO:0005887 integral component of plasma membrane IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0098794 postsynapse IEA
 molecular_functionGO:0001614 purinergic nucleotide receptor activity IBA
 molecular_functionGO:0004931 extracellularly ATP-gated cation channel activity IDA
 molecular_functionGO:0005216 ion channel activity IEA
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0035381 ATP-gated ion channel activity IDA


Pathways (from Reactome)
Pathway description
Elevation of cytosolic Ca2+ levels
Platelet homeostasis
The NLRP3 inflammasome


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2025
contact: otassy@igbmc.fr