ENSDARG00000010556


Danio rerio

Features
Gene ID: ENSDARG00000010556
  
Biological name :mmp25b
  
Synonyms : matrix metallopeptidase 25b / mmp25b
  
Possible biological names infered from orthology : matrix metallopeptidase 25 / Matrix metalloproteinase-25 / MMP25 / Q3U435 / Q9NPA2
  
Species: Danio rerio
  
Chr. number: 12
Strand: 1
Band:
Gene start: 4260779
Gene end: 4278329
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000075824
NCBI entrez gene - 100333601     See in Manteia.
swissprot - E7F1N5
ZFIN ID - ZDB-GENE-100308-4
Ensembl - ENSDARG00000010556
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 MMP25ENSG00000008516Homo sapiens
 Mmp25ENSMUSG00000023903Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
mmp25a / matrix metallopeptidase 25a / MMP25* / Q3U435* / Q9NPA2* / matrix metallopeptidase 25* / Matrix metalloproteinase-25 *ENSDARG0000007729048
mmp17a / matrix metallopeptidase 17a / MMP17* / Q9R0S3* / Q9ULZ9* / matrix metallopeptidase 17* / Matrix metalloproteinase-17 *ENSDARG0000007891538
mmp14b / matrix metallopeptidase 14b (membrane-inserted) / MMP14* / P50281* / P53690* / matrix metallopeptidase 14* / Matrix metalloproteinase-14 *ENSDARG0000000838834
mmp15b / matrix metallopeptidase 15b / MMP15* / P51511* / matrix metallopeptidase 15*ENSDARG0000001307234
mmp24 / matrix metallopeptidase 24 / Q9R0S2* / Q9Y5R2* / Matrix metalloproteinase-24 Processed matrix metalloproteinase-24*ENSDARG0000001889634
mmp17b / matrix metallopeptidase 17bENSDARG0000010295634
mmp14a / matrix metallopeptidase 14a (membrane-inserted) / MMP14* / P50281* / P53690* / matrix metallopeptidase 14* / Matrix metalloproteinase-14 *ENSDARG0000000223533
mmp15a / matrix metallopeptidase 15a / MMP15* / O54732* / P51511* / matrix metallopeptidase 15* / Matrix metalloproteinase-15 *ENSDARG0000005196233
mmp16b / matrix metallopeptidase 16b (membrane-inserted) / MMP16* / P51512* / Q9WTR0* / matrix metallopeptidase 16* / Matrix metalloproteinase-16 *ENSDARG0000005887632
mmp11b / matrix metallopeptidase 11b / MMP11* / P24347* / Q02853* / Stromelysin-3 * / matrix metallopeptidase 11*ENSDARG0000001671828
mmp11a / matrix metallopeptidase 11a / MMP11* / P24347* / Q02853* / Stromelysin-3 * / matrix metallopeptidase 11*ENSDARG0000002632527
mmp13b / matrix metallopeptidase 13b / MMP13* / P45452* / P33435* / Collagenase 3 * / matrix metallopeptidase 13*ENSDARG0000010079427
LO018336.1ENSDARG0000010840127
mmp13a / matrix metallopeptidase 13aENSDARG0000011445127
mmp13a / matrix metallopeptidase 13aENSDARG0000001239526
mmp30 / matrix metallopeptidase 30 / MMP7* / P09237* / matrix metallopeptidase 7*ENSDARG0000004588726
mmp20a / matrix metallopeptidase 20a (enamelysin) / MMP20* / O60882* / P57748* / matrix metallopeptidase 20* / Matrix metalloproteinase-20 *ENSDARG0000008988726
mmp20b / matrix metallopeptidase 20b (enamelysin)ENSDARG0000005547924


Protein motifs (from Interpro)
Interpro ID Name
 IPR000585  Hemopexin-like domain
 IPR001818  Peptidase M10, metallopeptidase
 IPR002477  Peptidoglycan binding-like
 IPR006026  Peptidase, metallopeptidase
 IPR018487  Hemopexin-like repeats
 IPR021190  Peptidase M10A
 IPR024079  Metallopeptidase, catalytic domain superfamily
 IPR028733  Matrix metalloproteinase-25
 IPR033739  Peptidase M10A, catalytic domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006508 proteolysis IEA
 biological_processGO:0006954 inflammatory response IEA
 biological_processGO:0097374 sensory neuron axon guidance IMP
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0031012 extracellular matrix IEA
 molecular_functionGO:0004222 metalloendopeptidase activity IEA
 molecular_functionGO:0008233 peptidase activity IEA
 molecular_functionGO:0008237 metallopeptidase activity IMP
 molecular_functionGO:0008270 zinc ion binding IEA
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
Activation of Matrix Metalloproteinases
Neutrophil degranulation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000295 trigeminal ganglion trigeminal ganglion axon misrouted , abnormal
Show

 ZFA:0000697 cranial nerve V cranial nerve V malformed , abnormal
Show

 ZFA:0000944 posterior lateral line posterior lateral line has fewer parts of type posterior lateral line neuromast , abnormal
Show

 ZFA:0005768 trigeminal sensory neuron trigeminal sensory neuron sensory neuron axon guidance decreased process quality , abnormal
trigeminal sensory neuron extracellular matrix disassembly decreased occurrence , abnormal
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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