ENSMUSG00000023903


Mus musculus

Features
Gene ID: ENSMUSG00000023903
  
Biological name :Mmp25
  
Synonyms : Matrix metalloproteinase-25 / Mmp25 / Q3U435
  
Possible biological names infered from orthology : matrix metallopeptidase 25 / Q9NPA2
  
Species: Mus musculus
  
Chr. number: 17
Strand: -1
Band: A3.3
Gene start: 23629458
Gene end: 23645269
  
Corresponding Affymetrix probe sets: 10448278 (MoGene1.0st)   
  
Cross references: Ensembl peptide - ENSMUSP00000024696
NCBI entrez gene - 240047     See in Manteia.
MGI - MGI:2443938
RefSeq - XM_017317466
RefSeq - NM_001033339
RefSeq - NM_001320258
RefSeq Peptide - NP_001307187
RefSeq Peptide - NP_001028511
swissprot - Q3U435
Ensembl - ENSMUSG00000023903
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 mmp25aENSDARG00000077290Danio rerio
 mmp25bENSDARG00000010556Danio rerio
 MMP25ENSG00000008516Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Mmp17 / Q9R0S3 / Matrix metalloproteinase-17 / Q9ULZ9* / matrix metallopeptidase 17*ENSMUSG0000002943642
Mmp15 / O54732 / Matrix metalloproteinase-15 / P51511* / matrix metallopeptidase 15*ENSMUSG0000003179034
Mmp14 / P53690 / Matrix metalloproteinase-14 / P50281* / matrix metallopeptidase 14*ENSMUSG0000000095733
Mmp24 / Q9R0S2 / Matrix metalloproteinase-24 Processed matrix metalloproteinase-24 / Q9Y5R2* / matrix metallopeptidase 24*ENSMUSG0000002761233
Mmp16 / Q9WTR0 / Matrix metalloproteinase-16 / P51512* / matrix metallopeptidase 16*ENSMUSG0000002822632
Mmp8 / O70138 / Neutrophil collagenase / P22894* / matrix metallopeptidase 8*ENSMUSG0000000580029
Mmp11 / Q02853 / Stromelysin-3 / P24347* / matrix metallopeptidase 11*ENSMUSG0000000090128
Mmp20 / P57748 / Matrix metalloproteinase-20 / O60882* / matrix metallopeptidase 20*ENSMUSG0000001862027
Mmp3 / matrix metallopeptidase 3ENSMUSG0000004361327
Mmp10 / O55123 / matrix metallopeptidase 10 / P09238*ENSMUSG0000004756227
Mmp1a / interstitial collagenase A preproprotein / MMP1* / P03956* / matrix metallopeptidase 1*ENSMUSG0000004308926
Mmp13 / P33435 / Collagenase 3 / P45452* / matrix metallopeptidase 13*ENSMUSG0000005057826
Mmp1b / MMP1* / P03956* / matrix metallopeptidase 1*ENSMUSG0000004162025
Mmp12 / P34960 / Macrophage metalloelastase / P39900* / matrix metallopeptidase 12*ENSMUSG0000004972325
Mmp27 / matrix metallopeptidase 27 / Q9H306*ENSMUSG0000007032325
Mmp7 / matrix metallopeptidase 7 / P09237*ENSMUSG0000001862317


Protein motifs (from Interpro)
Interpro ID Name
 IPR000585  Hemopexin-like domain
 IPR001818  Peptidase M10, metallopeptidase
 IPR002477  Peptidoglycan binding-like
 IPR006026  Peptidase, metallopeptidase
 IPR018487  Hemopexin-like repeats
 IPR021190  Peptidase M10A
 IPR024079  Metallopeptidase, catalytic domain superfamily
 IPR028733  Matrix metalloproteinase-25
 IPR033739  Peptidase M10A, catalytic domain
 IPR036365  PGBD-like superfamily
 IPR036375  Hemopexin-like domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006508 proteolysis ISO
 biological_processGO:0006954 inflammatory response IEA
 biological_processGO:0010952 positive regulation of peptidase activity IEA
 biological_processGO:0060022 hard palate development IMP
 cellular_componentGO:0005886 plasma membrane IDA
 cellular_componentGO:0009986 cell surface ISO
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0031012 extracellular matrix IEA
 cellular_componentGO:0031225 anchored component of membrane IEA
 molecular_functionGO:0004222 metalloendopeptidase activity IEA
 molecular_functionGO:0008233 peptidase activity IEA
 molecular_functionGO:0008237 metallopeptidase activity IEA
 molecular_functionGO:0008270 zinc ion binding IEA
 molecular_functionGO:0016504 peptidase activator activity ISO
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
Activation of Matrix Metalloproteinases
Neutrophil degranulation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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