ENSDARG00000012389


Danio rerio

Features
Gene ID: ENSDARG00000012389
  
Biological name :adar
  
Synonyms : adar / adenosine deaminase, RNA-specific
  
Possible biological names infered from orthology : Mus musculus adenosine deaminase, RNA-specific (Adar), transcript variant 4, mRNA. / P55265 / Q99MU3
  
Species: Danio rerio
  
Chr. number: 16
Strand: 1
Band:
Gene start: 23531583
Gene end: 23557714
  
Corresponding Affymetrix probe sets: Dr.10204.1.S1_at (Zebrafish Array)   
  
Cross references: Ensembl peptide - ENSDARP00000115965
NCBI entrez gene - 58119     See in Manteia.
swissprot - E9QIW2
ZFIN ID - ZDB-GENE-000616-5
Ensembl - ENSDARG00000012389
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ADARENSGALG00000021475Gallus gallus
 ADARENSG00000160710Homo sapiens
 AdarENSMUSG00000027951Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
adarb1b / adenosine deaminase, RNA-specific, B1b / ADARB1* / P78563* / Q91ZS8* / adenosine deaminase, RNA specific B1* / Double-stranded RNA-specific editase 1 *ENSDARG0000000354416
adarb1a / adenosine deaminase, RNA-specific, B1a / ADARB1* / P78563* / Q91ZS8* / adenosine deaminase, RNA specific B1* / Double-stranded RNA-specific editase 1 *ENSDARG0000004160916
adarb2 / adenosine deaminase, RNA-specific, B2 (non-functional) / Q9JI20* / Q9NS39* / adenosine deaminase, RNA-specific, B2* / adenosine deaminase, RNA specific B2 (inactive)*ENSDARG0000007182315
adad1 / adenosine deaminase domain containing 1 (testis-specific) / Q96M93* / adenosine deaminase domain containing 1*ENSDARG000000891819
adat1 / adenosine deaminase, tRNA-specific 1 / Q9BUB4* / Q9JHI2* / Mus musculus adenosine deaminase, tRNA-specific 1 (Adat1), transcript variant 3, mRNA.*ENSDARG000000613488
adad2 / adenosine deaminase domain containing 2 / Q8NCV1*ENSDARG000001056268


Protein motifs (from Interpro)
Interpro ID Name
 IPR000607  Double-stranded RNA-specific adenosine deaminase (DRADA)
 IPR002466  Adenosine deaminase/editase
 IPR011991  ArsR-like helix-turn-helix domain
 IPR014720  Double-stranded RNA-binding domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006396 RNA processing IEA
 molecular_functionGO:0003723 RNA binding IEA
 molecular_functionGO:0003726 double-stranded RNA adenosine deaminase activity IEA
 molecular_functionGO:0004000 adenosine deaminase activity IEA


Pathways (from Reactome)
Pathway description
C6 deamination of adenosine
Formation of editosomes by ADAR proteins


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000012389 adar / adenosine deaminase, RNA-specific / P55265* / Q99MU3* / Mus musculus adenosine deaminase, RNA-specific (Adar), transcript variant 4, mRNA.*  / complex / reaction






 

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