ENSGALG00000021475


Gallus gallus

Features
Gene ID: ENSGALG00000021475
  
Biological name :ADAR
  
Synonyms : ADAR / adenosine deaminase, RNA specific
  
Possible biological names infered from orthology : Mus musculus adenosine deaminase, RNA-specific (Adar), transcript variant 4, mRNA. / P55265 / Q99MU3
  
Species: Gallus gallus
  
Chr. number: 25
Strand: -1
Band:
Gene start: 1735967
Gene end: 1744372
  
Corresponding Affymetrix probe sets: Gga.8033.1.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000039924
NCBI entrez gene - 769675     See in Manteia.
RefSeq - XM_001232161
RefSeq - XM_004948259
swissprot - H9L3K3
Ensembl - ENSGALG00000021475
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 adarENSDARG00000012389Danio rerio
 ADARENSG00000160710Homo sapiens
 AdarENSMUSG00000027951Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
ADARB1 / adenosine deaminase, RNA specific B1 / P78563* / Q91ZS8* / Double-stranded RNA-specific editase 1 *ENSGALG0000000752731
ADARB2 / adenosine deaminase, RNA specific B2 (inactive) / Q9JI20* / Q9NS39* / adenosine deaminase, RNA-specific, B2*ENSGALG0000000679720
ADAD1 / adenosine deaminase domain containing 1 / Q5SUE7* / Q96M93* / Adenosine deaminase domain-containing protein 1 *ENSGALG0000004499520
ADAT1 / tRNA-specific adenosine deaminase 1 / Q9BUB4* / Q9JHI2* / adenosine deaminase, tRNA specific 1* / Mus musculus adenosine deaminase, tRNA-specific 1 (Adat1), transcript variant 3, mRNA.*ENSGALG0000000090815


Protein motifs (from Interpro)
Interpro ID Name
 IPR002466  Adenosine deaminase/editase
 IPR014720  Double-stranded RNA-binding domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001649 osteoblast differentiation IEA
 biological_processGO:0001701 in utero embryonic development IEA
 biological_processGO:0002244 hematopoietic progenitor cell differentiation IEA
 biological_processGO:0002566 somatic diversification of immune receptors via somatic mutation IEA
 biological_processGO:0006382 adenosine to inosine editing IEA
 biological_processGO:0006396 RNA processing IEA
 biological_processGO:0009615 response to virus IEA
 biological_processGO:0016553 base conversion or substitution editing IEA
 biological_processGO:0030218 erythrocyte differentiation IEA
 biological_processGO:0031054 pre-miRNA processing IEA
 biological_processGO:0035196 production of miRNAs involved in gene silencing by miRNA IEA
 biological_processGO:0035280 miRNA loading onto RISC involved in gene silencing by miRNA IEA
 biological_processGO:0035455 response to interferon-alpha IEA
 biological_processGO:0043066 negative regulation of apoptotic process IEA
 biological_processGO:0044387 negative regulation of protein kinase activity by regulation of protein phosphorylation IEA
 biological_processGO:0045070 positive regulation of viral genome replication IEA
 biological_processGO:0045071 negative regulation of viral genome replication IEA
 biological_processGO:0051607 defense response to virus IEA
 biological_processGO:0060216 definitive hemopoiesis IEA
 biological_processGO:0060339 negative regulation of type I interferon-mediated signaling pathway IEA
 biological_processGO:0061484 hematopoietic stem cell homeostasis IEA
 biological_processGO:0098586 cellular response to virus IEA
 biological_processGO:1900369 negative regulation of RNA interference IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005654 nucleoplasm IEA
 cellular_componentGO:0005730 nucleolus IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0044530 supraspliceosomal complex IEA
 molecular_functionGO:0003723 RNA binding IEA
 molecular_functionGO:0003726 double-stranded RNA adenosine deaminase activity IEA
 molecular_functionGO:0004000 adenosine deaminase activity IEA


Pathways (from Reactome)
Pathway description
C6 deamination of adenosine
Formation of editosomes by ADAR proteins


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSGALG00000021475 ADAR / adenosine deaminase, RNA specific / P55265* / Q99MU3* / Mus musculus adenosine deaminase, RNA-specific (Adar), transcript variant 4, mRNA.*  / complex / reaction






 

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