ENSDARG00000013755


Danio rerio

Features
Gene ID: ENSDARG00000013755
  
Biological name :actn3a
  
Synonyms : actinin alpha 3a / actn3a
  
Possible biological names infered from orthology : actinin alpha 3 (gene/pseudogene) / ACTN3 / Alpha-actinin-3 / O88990 / Q08043
  
Species: Danio rerio
  
Chr. number: 21
Strand: 1
Band:
Gene start: 27382893
Gene end: 27404978
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000005224
NCBI entrez gene - 58037     See in Manteia.
RefSeq - NM_131522
RefSeq Peptide - NP_571597
swissprot - D1GJ56
ZFIN ID - ZDB-GENE-000329-9
Ensembl - ENSDARG00000013755
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ACTN3ENSG00000248746Homo sapiens
 Actn3ENSMUSG00000006457Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
actn3b / actinin alpha 3b / ACTN3* / Q08043* / O88990* / Alpha-actinin-3 * / actinin alpha 3 (gene/pseudogene)*ENSDARG0000000143193
actn2b / actinin, alpha 2b / ACTN2* / P35609* / Q9JI91* / actinin alpha 2* / Alpha-actinin-2 *ENSDARG0000007109082
actn1 / actinin, alpha 1 / P12814* / Q7TPR4* / Mus musculus actinin, alpha 1 (Actn1), transcript variant 2, mRNA.*ENSDARG0000000721979
actn4 / actinin, alpha 4 / O43707*ENSDARG0000009978678
sptbn5 / spectrin, beta, non-erythrocytic 5 / Q9NRC6*ENSDARG0000009768331
sptbn2 / spectrin, beta, non-erythrocytic 2 / O15020*ENSDARG0000005395629
sptb / spectrin, beta, erythrocytic / P11277*ENSDARG0000003049028
sptbn1 / spectrin, beta, non-erythrocytic 1 / Q01082* / Q62261* / Spectrin beta chain, non-erythrocytic 1 *ENSDARG0000010288327
SPTBN4 / si:ch73-262h23.4 / Q9H254* / spectrin beta, non-erythrocytic 4*ENSDARG0000009262424
sptan1 / spectrin alpha, non-erythrocytic 1 / SPTA1* / Q13813* / P08032* / P16546* / P02549* / spectrin alpha, erythrocytic 1* / Spectrin alpha chain, erythrocytic 1 * / Spectrin alpha chai...ENSDARG0000001923118
si:dkey-27p18.5 / Q9H254* / SPTBN4* / spectrin beta, non-erythrocytic 4*ENSDARG000000686244
si:zfos-1837d3.1 / Q62261* / Q01082* / SPTBN1* / spectrin beta, non-erythrocytic 1* / Spectrin beta chain, non-erythrocytic 1 *ENSDARG000001054281
si:ch73-262h23.4 / Q9H254* / SPTBN4* / spectrin beta, non-erythrocytic 4*ENSDARG000001119421


Protein motifs (from Interpro)
Interpro ID Name
 IPR001589  Actinin-type actin-binding domain, conserved site
 IPR001715  Calponin homology domain
 IPR002017  Spectrin repeat
 IPR002048  EF-hand domain
 IPR011992  EF-hand domain pair
 IPR014837  EF-hand, Ca insensitive
 IPR018159  Spectrin/alpha-actinin


Gene Ontology (GO)
TypeGO IDTermEv.Code
 cellular_componentGO:0005575 cellular_component ND
 molecular_functionGO:0003779 actin binding IEA
 molecular_functionGO:0005509 calcium ion binding IEA


Pathways (from Reactome)
Pathway description
Striated Muscle Contraction


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000009 cardiac ventricle cardiac ventricle decreased contractility , abnormal
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 ZFA:0000114 heart heart decreased functionality , abnormal
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 ZFA:0000471 atrium atrium dilated , abnormal
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Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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